Browsing NTNU Open by Author "Ratner, Dmitry"

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    • Bacterial secretion systems and regulation of inflammasome activation 

      Ratner, Dmitry; Ørning, Mathias Pontus; Lien, Egil (Journal article, 2017)
      Innate immunity is critical for host defenses against pathogens, but many bacteria display complex ways of interacting with innate immune signaling, as they may both activate and evade certain pathways. Gram‐negative ...

    • The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation 

      Ratner, Dmitry; Ørning, Mathias Pontus; Proulx, MK; Wang, Donghai; Gavrilin, Mikhail; Wewers, Mark; Alnemri, Emad; Johnson, Peter; Lee, Bettina; Mecsas, Joan; Kayagaki, Nobuhiko; Goguen, JD; Lien, Egil (Journal article; Peer reviewed, 2016)
      Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative bacteria, and secreted T3SS effectors can block key aspects of host cell signaling. To counter this, innate immune responses ...