Browsing by Author "Rø, Torstein Baade"
Now showing items 1-15 of 15
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Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin
Olsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Mylin, Anne K.; Turesson, I; Størdal, Berit Fladvad; Moen, Siv Helen; Standal, Therese; Waage, Anders; Sundan, Anders; Holien, Toril (Journal article; Peer reviewed, 2014)Multiple myeloma is a malignancy of plasma cells predominantly located in the bone marrow. A number of bone morphogenetic proteins (BMPs) induce apoptosis in myeloma cells in vitro, and with this study we add BMP-9 to the ... -
Effects of bone morphogenetic proteins, hepatocyte growthfactor and interleukin-21 in multiple myeloma
Rø, Torstein Baade (Doktoravhandlinger ved NTNU, 1503-8181; 2006:4, Doctoral thesis, 2006)The studies presented in this thesis answer some questions, but also raise new questions which should be explored in future studies. The bone marrow microenvironment is a complex system, and is difficult to study in vitro. ... -
Effects of exercise intensity and nutrition advice on myocardial function in obese children and adolescents: a multicentre randomised controlled trial study protocol.
Dias, Katrin A.; Coombes, Jeff S; Green, DJ; Gomersall, SR; Keating, SE; Tjønna, Arnt Erik; Hollekim-Strand, Siri Marte; Hosseini, Mansoureh Sadat; Rø, Torstein Baade; Haram, M; Huuse, EM; Davies, PS; Cain, PA; Leong, GM; Ingul, Charlotte Bjørk (Journal article; Peer reviewed, 2016)Introduction The prevalence of paediatric obesity is increasing, and with it, lifestyle-related diseases in children and adolescents. High-intensity interval training (HIIT) has recently been explored as an alternate to ... -
Fear of hypoglycaemia and its relation to hypoglycaemia awareness and symptom intensity in Type 1 diabetes
Hatle, Håvard; Bjørgaas, Marit Ragnhild Rokne; Rø, Torstein Baade; Olsen, Sandra Elise; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2018)Aims To investigate fear of hypoglycaemia (FoH) in relation to hypoglycaemia awareness, history of severe hypoglycaemia (SH) and hypoglycaemia symptoms in adults with Type 1 diabetes. Methods Questionnaire-based ... -
Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration
Hjort, Magnus Aasved; Hov, Håkon; Abdollahi, Pegah; Vandsemb, Esten; Fagerli, Unn-Merete; Lund, Bendik; Slørdahl, Tobias Schmidt; Børset, Magne; Rø, Torstein Baade (Journal article; Peer reviewed, 2018)Background Phosphatase of regenerating liver-3 (PRL-3) is implicated in oncogenesis of hematological and solid cancers. PRL-3 expression increases metastatic potential, invasiveness and is associated with poor prognosis. ... -
Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migration
Vandsemb, Esten Nymoen; Bertilsson, Helena; Abdollahi, Pegah; Størkersen, Øystein; Våtsveen, Thea Kristin; Rye, Morten Beck; Rø, Torstein Baade; Børset, Magne; Slørdahl, Tobias Schmidt (Journal article; Peer reviewed, 2016)Background: PRL-3 is a phosphatase implicated in oncogenesis in multiple cancers. In some cancers, notably carcinomas, PRL-3 is also associated with inferior prognosis and increased metastatic potential. In this study we ... -
Phosphatase of regenerating liver-3 as a target for treatment of B cell malignancies
Hjort, Magnus Aassved (Doctoral theses at NTNU;2018:241, Doctoral thesis, 2018)PRL-3 som et angrepsmål i behandlingen av B-cellekreft Akutt lymfatisk leukemi (ALL), Hodgkin lymfom (HL) og myelomatose er kreftsykdommer som oppstår fra B-lymfocytter. Disse cellene er en del av kroppens immunforsvar. ... -
Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance
Hjort, Magnus Aassved; Abdollahi, Pegah; Vandsemb, Esten Nymoen; Fenstad, Mona H.; Lund, Bendik; Slørdahl, Tobias Schmidt; Børset, Magne; Rø, Torstein Baade (Journal article; Peer reviewed, 2017)Phosphatase of regenerating liver-3 (PRL-3/PTP4A3) is upregulated in multiple cancers, including BCR-ABL1- and ETV6-RUNX-positive acute lymphoblastic leukemia (ALL). With this study, we aim to characterize the biological ... -
PRL-3–a signaling hub in Multiple Myeloma
Abdollahi, Pegah (Doctoral theses at NTNU;2017:131, Doctoral thesis, 2017)PRL-3 -en sentral aktør i myelomatsoecellens signalformidling: Myelomatose er en kreftform som oppstår i plasmaceller, den ferdig differensierte formen for B lymfocytter. Et kjennetegn på myelomatose er dens lokalisasjon ... -
Reduced Th22 cell proportion and prevention of atopic dermatitis in infants following maternal probiotic supplementation
Rø, Anne Dorthea; Simpson, Melanie Rae; Rø, Torstein Baade; Storrø, Ola; Johnsen, Roar; Videm, Vibeke; Øien, Torbjørn (Journal article; Peer reviewed, 2017)Background In the randomized, controlled study Probiotics in the Prevention of Allergy among Children in Trondheim (ProPACT), maternal probiotic supplementation reduced the incidence of atopic dermatitis (AD) in the ... -
Requests for new oral antibiotic prescriptions in children within 2 days: a Norwegian population-based study
Bergene, Elin Høien; Nordeng, Hedvig Marie Egeland; Rø, Torstein Baade; Steinsbekk, Aslak (Journal article; Peer reviewed, 2018)Background Children commonly refuse to take antibiotics, which may induce parents to request new antibiotic prescriptions with different pharmaceutical characteristics. Objectives To investigate prescription changes ... -
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3
Abdollahi, Pegah; Vandsemb, Esten Nymoen; Hjort, Magnus Aassved; Misund, Kristine; Holien, Toril; Sponaas, Anne-Marit; Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Børset, Magne (Journal article; Peer reviewed, 2016)Phosphatase of regenerating liver-3 (PTP4A3/PRL-3) is a dual-specificity phosphatase that is upregulated in various types of cancers and is related to poor prognosis and aggressive tumor behavior. The expression level of ... -
Strategies parents use to give children oral medicine: a qualitative study of online discussion forums
Bergene, Elin Høien; Rø, Torstein Baade; Steinsbekk, Aslak (Journal article; Peer reviewed, 2017)Aim: The aim of this study was to describe strategies parents use to give oral medicine to children. Methods: We conducted an Internet-based qualitative study of posts from online forums where parents discussed how to give ... -
Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells
Müller, Rebekka; Misund, Kristine; Holien, Toril; Bachke, Siri; Gilljam, Karin Margaretha; Våtsveen, Thea Kristin; Rø, Torstein Baade; Bellacchio, E.; Sundan, Anders; Otterlei, Marit (Journal article; Peer reviewed, 2013)Multiple myeloma is a hematological cancer that is considered incurable despite advances in treatment strategy during the last decade. Therapies targeting single pathways are unlikely to succeed due to the heterogeneous ... -
Use of oral medicines for short-term illnesses in children - Perspectives on prescribing, dispensing and administration
Bergene, Elin Høien (Doctoral theses at NTNU;2018:332, Doctoral thesis, 2018)Summary About half of all children receive one or more prescriptions per year, most commonly oral medicines for short-term illnesses. Choosing an appropriate medicine for a specific child can be challenging due to the ...