Blar i NTNU Open på forfatter "Räikkönen, Katri"
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ADHD symptoms and diagnosis in adult preterms: systematic review, IPD meta-analysis, and register-linkage study
Robinson, Rachel; Girchenko, Polina; Pulakka, Anna; Heinonen, Kati; Lähdepuro, Anna; Lahti-Pulkkinen, Marius; Hovi, Petteri; Tikanmäki, Marjaana; Bartmann, Peter; Lano, Aulikki; Doyle, Lex W.; Anderson, Peter J.; Cheong, Jeanie L. Y.; Darlow, Brian A.; Woodward, Lianne J.; Horwood, L. John; Indredavik, Marit Sæbø; Evensen, Kari Anne Indredavik; Marlow, Neil; Johnson, Samantha; de Mendonca, Marina Goulart; Kajantie, Eero Olavi; Wolke, Dieter; Räikkönen, Katri (Peer reviewed; Journal article, 2022)Background This study examined differences in ADHD symptoms and diagnosis between preterm and term-born adults (≥18 years), and tested if ADHD is related to gestational age, birth weight, multiple births, or neonatal ... -
Antenatal corticosteroid treatment and infectious diseases in children: a nationwide observational study
Räikkönen, Katri; Gissler, Mika; Kajantie, Eero Olavi; Tapiainen, Terhi (Peer reviewed; Journal article, 2023)Background Antenatal Corticosteroid Treatment (ACT) improves the outcome of preterm infants, but may influence immune system development and risk of immune-related diseases. We investigated whether ACT is associated ... -
Association of very preterm birth or very low birth weight with intelligence in adulthood: an individual participant data meta-analysis
Eves, Robert; Mendonça, Marina; Baumann, Nicole; Ni, Yanyan; Darlow, Brian; Horwood, John; Woodward, Lianne J.; Doyle, Lex W.; Cheong, Jeanie; Anderson, Peter J.; Bartmann, Peter; Marlow, Neil; Johnson, Samantha; Kajantie, Eero Olavi; Hovi, Petteri; Nosarti, Chiara; Indredavik, Marit Sæbø; Evensen, Kari Anne Indredavik; Räikkönen, Katri; Heinonen, Kati; Zeitlin, Jennifer; Wolke, Dieter (Peer reviewed; Journal article, 2021)Importance Birth before 32 weeks’ gestation (very preterm [VPT]) and birth weight below 1500 g (very low birth weight [VLBW]) have been associated with lower cognitive performance in childhood. However, there are few ... -
Associations between Maternal Antenatal Corticosteroid Treatment and Psychological Developmental and Neurosensory Disorders in Children
Räikkönen, Katri; Gissler, Mika; Tapiainen, Terhi; Kajantie, Eero Olavi (Peer reviewed; Journal article, 2022)Importance Corticosteroids administered to women at risk of imminent preterm birth is one of the most effective ways to improve the prognosis of infants born preterm. Scant data about long-term neurodevelopmental and ... -
Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation
Czamara, Darina; Dieckmann, Linda; Röh, Simone; Kraemer, Sarah; Rancourt, Rebecca C.; Sammallahti, Sara; Kajantie, Eero Olavi; Laivuori, Hannele; Eriksson, Johan G.; Räikkönen, Katri; Henrich, Wolfgang; Plagemann, Andreas; Binder, Elisabeth B.; Braun, Thorsten; Entringer, Sonja (Peer reviewed; Journal article, 2021)Background Glucocorticoids (GCs) play a pivotal role in fetal programming. Antenatal treatment with synthetic GCs (sGCs) in individuals in danger of preterm labor is common practice. Adverse short- and long-term effects ... -
Brain Volumes and Abnormalities in Adults Born Preterm at Very Low Birth Weight
Kuula, Juho; Martola, Juha; Hakkarainen, Antti; Räikkönen, Katri; Savolainen, Sauli; Salli, Eero; Hovi, Petteri; Björkqvist, Johan; Kajantie, Eero Olavi; Lundbom, Nina (Journal article; Peer reviewed, 2022) -
Common Core Assessments in follow‐up studies of adults born preterm—Recommendation of the Adults Born Preterm International Collaboration
Kajantie, Eero Olavi; Johnson, Samantha; Heinonen, Kati; Anderson, Peter J.; Wolke, Dieter; Evensen, Kari Anne Indredavik; Räikkönen, Katri; Darlow, Brian A.; Van Der Pal, Sylvia; Indredavik, Marit Sæbø; Jaekel, Julia; Hovi, Petteri; Morrison, Katherine M.; Verrips, Erik; Doyle, Lex W. (Journal article; Peer reviewed, 2020) -
Effect of High-Dose vs Standard-Dose Vitamin D Supplementation on Neurodevelopment of Healthy Term Infants: A Randomized Clinical Trial
Tuovinen, Soile; Räikkönen, Katri; Holmlund-Suila, Elisa; Hauta-Alus, Helena; Helve, Otto; Rosendahl, Jenni; Enlund-Cerullo, Maria; Kajantie, Eero Olavi; Valkama, Saara; Viljakainen, Heli; Mäkitie, Outi; Andersson, Sture; Heinonen, Kati (Peer reviewed; Journal article, 2021)Importance Vitamin D may be important for neurodevelopment. The optimal daily dose of vitamin D for early brain development is not known. Objectives To test whether a higher (1200 IU) vs standard (400 IU) dose of ... -
Effect of Vitamin D3 Supplementation in the First 2 Years of Life on Psychiatric Symptoms at Ages 6 to 8 Years: A Randomized Clinical Trial
Sandboge, Samuel; Räikkönen, Katri; Lahti-Pulkkinen, Marius; Hauta-Alus, Helena; Holmlund-Suila, Elisa; Girchenko, Polina; Kajantie, Eero Olavi; Mäkitie, Outi; Andersson, Sture; Heinonen, Kati (Peer reviewed; Journal article, 2023)Importance Vitamin D is associated with neurodevelopment, but causality, critical windows, and potentials for modification remain unknown. Objective To determine the impact of high-dose (1200 IU) vs standard-dose (400 ... -
Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing
Czamara, Darina; Cruceanu, Cristiana; Lahti-Pulkkinen, Marius; Dieckmann, Linda; Ködel, Maik; Sauer, Susann; Rex-Haffner, Monika; Sammallahti, Sara; Kajantie, Eero Olavi; Laivuori, Hannele; Lahti, Jari; Räikkönen, Katri; Binder, Elisabeth B. (Peer reviewed; Journal article, 2022)Several studies have shown that children from pregnancies with estimated first-trimester risk based on fetal nuchal translucency thickness and abnormal maternal serum pregnancy protein and hormone levels maintain a higher ... -
Heavier smoking may lead to a relative increase in waist circumference: Evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium
Morris, Richard W.; Taylor, Amy E.; Fluharty, Meg E.; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Gabrielsen, Maiken Elvestad; Campbell, Archie; Marioni, Riccardo; Kumari, Meena; Korhonen, Tellervo; Männistö, Satu; Marques-Vidal, Pedro; Kaakinen, Marika; Cavadino, Alana; Postmus, Iris; Husemoen, Lise Lotte N.; Skaaby, Tea; Ahluwalia, Tarun Veer Singh; Treur, Jorien L.; Willemsen, Gonneke; Dale, Caroline; Wannamethee, S. Goya; Lahti, Jari; Palotie, Aarno; Räikkönen, Katri; McConnachie, Alex; Padmanabhan, Sandosh; Wong, Andrew; Dalgård, Christine; Paternoster, Lavinia; Ben-Shlomo, Yoav; Tyrrell, Jessica; Horwood, John; Fergusson, David M.; Kennedy, Martin A.; Nohr, Ellen A.; Christiansen, Lene; Kyvik, Kirsten Ohm; Kuh, Diana; Watt, Graham; Eriksson, Johan G.; Whincup, Peter H.; Vink, Jacqueline M.; Boomsma, Dorret I.; Smith, George Davey; Lawlor, Debbie; Linneberg, Allan; Ford, Ian; Jukema, J. Wouter; Power, Chris; Hyppönen, Elina; Jarvelin, Marjo-Riitta; Preisig, Martin; Borodulin, Katja; Kaprio, Jaakko; Kivimaki, Mika; Smith, Blair H.; Hayward, Caroline; Romundstad, Pål Richard; Sørensen, Thorkild I.A.; Munafo, Marcus R.; Sattar, Naveed (Journal article; Peer reviewed, 2015)Objectives: To investigate, using a Mendelian randomisation approach, whether heavier smoking is associated with a range of regional adiposity phenotypes, in particular those related to abdominal adiposity. Design: ... -
Maternal exposure to childhood maltreatment and mental and behavioral disorders in children
Airikka, Aino; Lahti-Pulkkinen, Marius; Tuovinen, Soile; Heinonen, Kati; Lahti, Jari; Girchenko, Polina; Lähdepuro, Anna; Pyhälä, Riikka; Czamara, Darina; Villa, Pia; Laivuori, Hannele; Kajantie, Eero Olavi; Binder, Elisabeth B.; Räikkönen, Katri (Peer reviewed; Journal article, 2022)Exposure to maltreatment in childhood is associated with lifelong risk of mental and behavioral disorders. Whether the effects extend to the next generation remains unclear. We examined whether maternal exposure to childhood ... -
Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium
Ronkainen, Justiina; Heiskala, Anni; Vehmeijer, Florianne O.; Lowry, Estelle; Caramaschi, Doretta; Estrada Gutierrez, Guadalupe; Heiss, Jonathan A.; Hummel, Nadine; Keikkala, Elina; Kvist, Tuomas; Kupsco, Allison; Melton, Phillip E.; Pesce, Giancarlo; Soomro, Munawar Hussain; Vives-Usano, Marta; Baïz, Nour; Binder, Elisabeth B.; Czamara, Darina; Guxens, Mònica; Mustaniemi, Sanna; London, Stephanie J.; Rauschert, Sebastian; Vääräsmäki, Marja; Vrijheid, Martine; Ziegler, Anette-G.; Annesi-Maesano, Isabella; Bustamante, Mariona; Huang, Rae-Chi; Hummel, Sandra; Just, Allan C.; Kajantie, Eero Olavi; Lahti, Jari; Lawlor, Debbie A.; Räikkönen, Katri; Jarvelin, Marjo-Riitta; Felix, Janine F.; Sebert, Sylvain (Peer reviewed; Journal article, 2021)Altered maternal haemoglobin levels during pregnancy are associated with pre-clinical and clinical conditions affecting the fetus. Evidence from animal models suggests that these associations may be partially explained by ... -
Maternal mental health and adverse birth outcomes
Voit, Falk A.C.; Kajantie, Eero Olavi; Lemola, Sakari; Räikkönen, Katri; Wolke, Dieter; Schnitzlein, Daniel D. (Peer reviewed; Journal article, 2022)Recent research in economics emphasizes the role of in utero conditions for the health endowment at birth and in early childhood and for social as well as economic outcomes in later life. This paper analyzes the relation ... -
Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring
Kaseva, Nina; Vääräsmäki, Marja; Matinolli, Hanna-Maria; Sipola, Marika; Tikanmäki, Marjaana; Kanerva, Noora; Heinonen, Kati; Lano, Aulikki; Wolke, Dieter; Andersson, Sture; Järvelin, Marjo-Riitta; Räikkönen, Katri; Eriksson, Johan G.; Männistö, Satu; Kajantie, Eero Olavi (Peer reviewed; Journal article, 2020)Background/Objectives Maternal pre-pregnancy overweight/obesity and gestational diabetes (GDM) are associated with increased fat deposition in adult offspring. The purpose of this study was to identify if maternal ... -
A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders
Suarez, Anna; Lahti, Jari; Lahti-Pulkkinen, Marius; Girchenko, Polina; Czamara, Darina; Arloth, Janine; Malmberg, Anni LK.; Hämäläinen, Esa; Kajantie, Eero Olavi; Laivuori, Hannele; Villa, Pia M.; Reynolds, Rebecca M.; Provençal, Nadine; Binder, Elisabeth B.; Räikkönen, Katri (Peer reviewed; Journal article, 2020)Background Maternal depression and anxiety during pregnancy may enhance fetal exposure to glucocorticoids (GCs) and harm neurodevelopment. We tested whether a novel cross-tissue polyepigenetic biomarker indicative of in ... -
Positive maternal mental health during pregnancy and mental and behavioral disorders in children: A prospective pregnancy cohort study
Lähdepuro, Anna; Lahti-Pulkkinen, Marius; Pyhälä, Riikka; Tuovinen, Soile; Lahti, Jari; Heinonen, Kati; Laivuori, Hannele; Villa, Pia M.; Reynolds, Rebecca M.; Kajantie, Eero Olavi; Girchenko, Polina; Räikkönen, Katri (Journal article; Peer reviewed, 2022) -
A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation
Li, Shaobo; Spitz, Natalia; Ghantous, Akram; Abrishamcar, Sarina; Reimann, Brigitte; Marques, Irene; Silver, Matt J.; Aguilar-Lacasaña, Sofía; Kitaba, Negusse; Rezwan, Faisal I.; Röder, Stefan; Sirignano, Lea; Tuhkanen, Johanna; Mancano, Giulia; Sharp, Gemma C.; Metayer, Catherine; Morimoto, Libby; Stein, Dan J.; Zar, Heather J.; Alfano, Rossella; Nawrot, Tim; Wang, Congrong; Kajantie, Eero Olavi; Keikkala, Elina; Mustaniemi, Sanna; Ronkainen, Justiina; Sebert, Sylvain; Silva, Wnurinham; Vääräsmäki, Marja; Jaddoe, Vincent W. V.; Bernstein, Robin M.; Prentice, Andrew M.; Cosin-Tomas, Marta; Dwyer, Terence; Håberg, Siri Eldevik; Herceg, Zdenko; Magnus, Maria Christine; Munthe-Kaas, Monica Cheng; Page, Christian Magnus; Völker, Maja; Gilles, Maria; Send, Tabea; Witt, Stephanie; Zillich, Lea; Gagliardi, Luigi; Richiardi, Lorenzo; Czamara, Darina; Räikkönen, Katri; Chatzi, Lida; Vafeiadi, Marina; Arshad, S. Hasan; Ewart, Susan; Plusquin, Michelle; Felix, Janine F.; Moore, Sophie E.; Vrijheid, Martine; Holloway, John W.; Karmaus, Wilfried; Herberth, Gunda; Zenclussen, Ana; Streit, Fabian; Lahti, Jari; Hüls, Anke; Hoang, Thanh T.; London, Stephanie J.; Wiemels, Joseph L. (Peer reviewed; Journal article, 2024)Higher birth order is associated with altered risk of many disease states. Changes in placentation and exposures to in utero growth factors with successive pregnancies may impact later life disease risk via persistent DNA ... -
Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studies
Dieckmann, Linda; Cruceanu, Cristiana; Lahti-Pulkkinen, Marius; Lahti, Jari; Kvist, Tuomas; Laivuori, Hannele; Sammallahti, Sara; Villa, Pia M.; Suomalainen-König, Sanna; Rancourt, Rebecca C.; Plagemann, Andreas; Henrich, Wolfgang; Eriksson, Johan G.; Kajantie, Eero Olavi; Entringer, Sonja; Braun, Thorsten; Räikkönen, Katri; Binder, Elisabeth B.; Czamara, Darina (Peer reviewed; Journal article, 2022)The placenta is a central organ during early development, influencing trajectories of health and disease. DNA methylation (DNAm) studies of human placenta improve our understanding of how its function relates to disease ... -
Risk-taking behavior of adolescents and young adults born preterm
Alenius, Suvi; Kajantie, Eero Olavi; Sund, Reijo; Nurhonen, Markku; Haaramo, Peija; Näsänen-Gilmore, Pieta; Vääräsmäki, Marja; Lemola, Sakari; Räikkönen, Katri; Schnitzlein, Daniel D.; Wolke, Dieter; Gissler, Mika; Hovi, Petteri (Peer reviewed; Journal article, 2023)Objectives To study sexually transmitted Chlamydia trachomatis infections (STCTs), teenage pregnancies, and payment defaults in individuals born preterm as proxies for engaging in risk-taking behavior. Study design Our ...