Browsing NTNU Open by Author "Pukkala, Eero"
Now showing items 1-12 of 12
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Antireflux surgery and risk of lung cancer by histological type in a multinational cohort study
Yanes, Manar; Giola, Santoni; Maret-Ouda, John; Ness-Jensen, Eivind; Färkkilä, Martti; Lynge, Elsebeth; Nwaru, Bright I.; Pukkala, Eero; Romundstad, Pål Richard; Tryggvadóttir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper (Peer reviewed; Journal article, 2020)Introduction Airway micro-aspiration might contribute to the proposed associations between gastroesophageal reflux disease (GERD) and some lung diseases, including lung cancer. This study aimed to examine the hypothesis ... -
Cancer Risk After Bariatric Surgery in a Cohort Study from the Five Nordic Countries
Tao, Wenjing; Giola, Santoni; von Euler-Chelpin, My; Ljung, Rickard; Lynge, Elsebeth; Pukkala, Eero; Ness-Jensen, Eivind; Romundstad, Pål Richard; Tryggvadóttir, Laufey; Lagergren, Jesper (Peer reviewed; Journal article, 2020)Purpose Obesity increases the risk of several cancers, but the influence of bariatric surgery on the risk of individual obesity-related cancers is unclear. This study aimed to assess the impact of bariatric surgery on ... -
Cohort profile: The Nordic Antireflux Surgery Cohort (NordASCo)
Maret-Ouda, John; Wahlin, Karl; Artama, Miia; Brusselaers, Nele; Färkkilä, Martti; Lynge, Elsebeth; Mattsson, Fredrik; Pukkala, Eero; Romundstad, Pål Richard; Tryggvadóttir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper (Journal article; Peer reviewed, 2017)Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having ... -
Effects of Obesity Surgery on Overall and Disease-Specific Mortality in a 5-Country Population-Based Study
Kauppila, Joonas H.; Tao, Wenjing; Santoni, Giola; von Euler-Chelpin, My; Lynge, Elsebeth; Tryggvadóttir, Laufey; Ness-Jensen, Eivind; Romundstad, Pål Richard; Pukkala, Eero; Lagergren, Jesper (Journal article; Peer reviewed, 2019)Background & Aims Bariatric surgery might reduce overall mortality from obesity. We investigated whether the survival times of patients who have had bariatric surgery are similar to those of the general population and are ... -
Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci
Tanskanen, Tomas; Van Den Berg, Linda; Välimäki, Niko; Aavikko, Mervi; Ness-Jensen, Eivind; Hveem, Kristian; Wettergren, Yvonne; Lindskog, Elinor Bexe; Tönisson, Neeme; Metspalu, Andres; Silander, Kaisa; Orlando, Giulia; Law, Philip J.; Tuupanen, Sari; Gylfe, Alexandra E.; Hänninen, Ulrika A.; Cajuso, Tatiana; Kondelin, Johanna; Sarin, Antti-Pekka; Pukkala, Eero; Jousilahti, Pekka; Salomaa, Veikko; Ripatti, Samuli; Palotie, Aarno; Järvinen, Heikki; Renkonen-Sinisalo, Laura; Lepistö, Anna; Böhm, Jan; Mecklin, Jukka-Pekka; Al-Tassan, Nada A.; Palles, Claire; Martin, Lynn; Barclay, Ella; Tenesa, Albert; Farrington, Susan M.; Timofeeva, Maria N.; Meyer, Brian F; Wakil, Salma M.; Campbell, Harry; Smith, Christopher G.; Idziaszczyk, Shelley; Maughan, Tim S.; Kaplan, Richard; Kerr, Rachel; Kerr, David; Buchanan, Daniel D.; Win, Aung K.; Hopper, John; Jenkins, Mark A.; Newcomb, Polly A.; Gallinger, Steve; Conti, David; Schumacher, Fredrick R.; Casey, Graham; Cheadle, Jeremy P.; Dunlop, Malcolm G.; Tomlinson, Ian P; Houlston, Richard S.; Palin, Kimmo; Aaltonen, Lauri (Journal article; Peer reviewed, 2018)Genome-wide association studies have been successful in elucidating the genetic basis of colorectal cancer (CRC), but there remains unexplained variability in genetic risk. To identify new risk variants and to confirm ... -
Hospital Volume of Antireflux Surgery in Relation to Endoscopic and Surgical Re-interventions
Markar, Sheraz; Santoni, Giola; Maret-Ouda, John; Artama, Miia; Färkkilä, Martti; Lynge, Elsebeth; Pukkala, Eero; Ness-Jensen, Eivind; von Euler-Chelpin, My; Lagergren, Jesper (Journal article; Peer reviewed, 2020)Objective: To test the hypothesis that higher hospital volume decreases endoscopic and surgical re-intervention rates after antireflux surgery. Background: Antireflux surgery for gastro-esophageal reflux disease is ... -
Laryngeal and Pharyngeal Squamous Cell Carcinoma After Antireflux Surgery in the 5 Nordic Countries
Yanes, Manar; Giola, Santoni; Maret-Ouda, John; Ness-Jensen, Eivind; Färkkilä, Martti A.; Lynge, Elsebeth; Pukkala, Eero; Romundstad, Pål Richard; Tryggvadottir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper (Peer reviewed; Journal article, 2020)Objective: The aim of this study was to clarify whether antireflux surgery prevents laryngeal and pharyngeal squamous cell carcinoma. Summary Background Data: Gastroesophageal reflux disease (GERD) seems to increase ... -
Mortality, Reoperation, and Hospital Stay Within 90 Days of Primary and Secondary Antireflux Surgery in a Population-Based Multinational Study
Yanes, Manar; Santoni, Giola; Maret-Ouda, John; Markar, Sheraz; Ness-Jensen, Eivind; Kauppila, Joonas H.; Färkkilä, Martti; Lynge, Elsebeth; Pukkala, Eero; Tryggvadottir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper (Peer reviewed; Journal article, 2021)Background & Aims Absolute rates and risk factors of short-term outcomes after antireflux surgery remain largely unknown. We aimed to clarify absolute risks and risk factors for poor 90-day outcomes of primary laparoscopic ... -
Reintervention or mortality within 90 days of bariatric surgery: population-based cohort study
Kauppila, Joonas H.; Giola, Santoni; Tao, Wenjing; Lynge, Elsebeth; Koivukangas, Vesa; Tryggvadóttir, Laufey; Ness-Jensen, Eivind; Romundstad, Pål Richard; Pukkala, Eero; von Euler-Chelpin, My; Lagergren, Jesper (Peer reviewed; Journal article, 2020)Background Bariatric surgery carries a risk of severe postoperative complications, sometimes leading to reinterventions or even death. The incidence and risk factors for reintervention and death within 90 days after ... -
Risk Factors for Suicide After Bariatric Surgery in a Population-based Nationwide Study in Five Nordic Countries
Kauppila, Joonas H.; Giola, Santoni; Tao, Wenjing; Lynge, Elsebeth; Jokinen, Jussi; Tryggvadóttir, Laufey; Ness-Jensen, Eivind; Pukkala, Eero; von Euler-Chelpin, My; Lagergren, Jesper (Peer reviewed; Journal article, 2020)Objective: To identify risk factors for suicide after bariatric surgery. Summary background data: Bariatric surgery reduces obesity-related mortality. However, it is for unclear reasons is associated with an increased ... -
Shared environment and colorectal cancer: A Nordic pedigree registry-based cohort study
Elmahdi, Rahma; Wennerström, Elna C. M.; Andersson, Mikael; Wohlfahrt, Jan; Melbye, Mads; Pukkala, Eero; Hortlund, Maria; Silander, Kaisa; Sutinen, Kyösti; Jess, Tine; Dillner, Joakim (Peer reviewed; Journal article, 2022)Risk of colorectal cancer (CRC) increases in relatives of patients with CRC. The extent to which this is attributable to genetic predisposition or shared environment is unclear. We explored this question using nationwide ... -
Survival after antireflux surgery versus medication in patients with reflux oesophagitis or Barrett's oesophagus: multinational cohort study
Yanes, M.; Santoni, Giola; Maret-Ouda, John; Ness-Jensen, E.; Färkkilä, Martti; Lynge, Elsebeth; Pukkala, Eero; Romundstad, P.; Tryggvadottir, Laufey; -Chelpin, M von Euler; Lagergren, Jesper (Peer reviewed; Journal article, 2021)Background The aim was to examine the hypothesis that antireflux surgery with fundoplication improves long-term survival compared with antireflux medication in patients with reflux oesophagitis or Barrett’s oesophagus. ...