Browsing NTNU Open by Author "Pinho, Maria"
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Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial
Smenes, Benedikte; Bækkerud, Fredrik Hjulstad; Slagsvold, Katrine Hordnes; Hassel, Erlend; Wohlwend, Martin; Pinho, Maria; Høydal, Morten; Wisløff, Ulrik; Rognmo, Øivind; Wahba, Alexander (Journal article; Peer reviewed, 2018)OBJECTIVES During open-heart surgery, the myocardium experiences ischaemia–reperfusion injury. A single bout of moderate, 30-min exercise induces preconditioning and protects the heart from ischaemia–reperfusion injury ... -
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
Scrimgeour, Nathan Robert; Wrobel, Aleksandra Zofia; Pinho, Maria; Høydal, Morten (Peer reviewed; Journal article, 2019)Matrix metalloproteinases (MMP) are important for cardiac remodeling. Recently, microRNA (miR)-451a has been found to inhibit the expression of both MMP-2 and MMP-9 in human malignancies, but its role in cardiomyocytes has ...