Browsing NTNU Open by Author "Pigni, Alessandra"
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Depression-A Major Contributor to Poor Quality of Life in Patients With Advanced Cancer
Grotmol, Kjersti Støen; Lie, Hanne Cathrine; Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Currow, David; Kaasa, Stein; Moum, Torbjørn Åge; Pigni, Alessandra; Loge, Jon Håvard (Journal article, 2017)Context Quality of life (QoL) and depression are important patient-reported outcomes in cancer care. However, the relative importance of depression severity in predicting QoL remains unclear because of few methodologically ... -
Genomic Study in Opioid-Treated Cancer Patients Identifies Variants Associated With Nausea-Vomiting
Minnai, Francesca; Shkodra, Morena; Noci, Sara; Brunelli, Cinzia; Pigni, Alessandra; Zecca, Ernesto; Skorpen, Frank; Klepstad, Pål; Kaasa, Stein; Corli, Oscar; Pallotti, Maria Caterina; Maltoni, Marco Cesare; Caraceni, Augusto Tomasso Giovanni; Colombo, Francesca (Peer reviewed; Journal article, 2024)Context Opioids are the mainstay therapy for patients affected by cancer pain. However, about 10%–20% of patients do not benefit from the received analgesic treatment or experience side effects. Genetic variability might ... -
Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients
Colombo, Francesca; Pintarelli, Giulia; Galvan, Antonella; Noci, Sara; Corli, Oscar; Skorpen, Frank; Klepstad, Pål; Kaasa, Stein; Pigni, Alessandra; Brunelli, Cinzia; Roberto, Anna; Piazza, Rocco; Pirola, Alessandra; Gambacorti-Passerini, Carlo; Caraceni, Augusto Tomasso Giovanni (Peer reviewed; Journal article, 2020)Nausea and vomiting are often associated with opioid analgesia in cancer patients; however, only a subset of patients develop such side effects. Here, we tested the hypothesis that the occurrence of nausea and vomiting is ...