Browsing NTNU Open by Author "Paulsen, Ørnulf"
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Corticosteroids for Cancer Pain
Paulsen, Ørnulf (Doctoral theses at NTNU;2017:117, Doctoral thesis, 2017) -
An exploratory study examining the relationship between performance status and systemic inflammation frameworks and cytokine profiles in patients with advanced cancer
Dolan, Ross D.; Laird, Barry J.A.; Klepstad, Pål; Kaasa, Stein; Horgan, Paul G.; Paulsen, Ørnulf; McMillan, Donald C. (Peer reviewed; Journal article, 2019)The role of cytokines in the systemic inflammatory response (SIR) is now well established. This is in keeping with the role of the SIR in tumorigenesis, malignant spread, and the development of cachexia. However, the ... -
PALLiative care in ONcology (PALLiON): A cluster-randomised trial investigating the effect of palliative care on the use of anticancer treatment at the end of life
Hjermstad, Marianne Jensen; Pirnat, Aleksandra; Aass, Nina Kathrine; Andersen, Sigve; Astrup, Guro Lindviksmoen; Dajani, Olav; Garresori, Herish; Guldhav, Kristin Vassbotn; Hamre, Hanne Mari; Haukland, Ellinor Christin; Jordal, Frode; Lundeby, Tonje; Løhre, Erik Torbjørn; Mjåland, Svein; Paulsen, Ørnulf; Semb, Karin; Staff, Erik Schistad; Wester, Torunn Elin; Kaasa, Stein (Journal article; Peer reviewed, 2024)Background: Effects on anticancer therapy following the integration of palliative care and oncology are rarely investigated. Thus, its potential effect is unknown. Aim: To investigate the effects of the complex intervention ... -
PALLiON - PALLiative care Integrated in ONcology: Study protocol for a Norwegian national cluster-randomized control trial with a complex intervention of early integration of palliative care
Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Andersen, Sigve; Brunelli, Cinzia; Dajani, Olav; Ahmed, Herish; Hamre, Hanne Mari; Haukland, Ellinor Christin; Holmberg, Mats; Jordal, Frode; Krogstad, Hilde; Lundeby, Tonje; Løhre, Erik T; Mjåland, Svein; Nordbø, Arve; Paulsen, Ørnulf; Staff, Erik Schistad; Wester, Torunn; Kaasa, Stein; Loge, Jon Håvard (Peer reviewed; Journal article, 2020)Background - Several publications have addressed the need for a systematic integration of oncological care focused on the tumor and palliative care (PC) focused on the patient with cancer. The exponential increase in ... -
The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial
Jakobsen, Gunnhild; Engstrøm, Morten; Hjermstad, Marianne Jensen; Rosland, Jan Henrik; Aass, Nina Kathrine; Albert, Eva; Kaasa, Stein; Fayers, Peter; Klepstad, Pål; Paulsen, Ørnulf (Peer reviewed; Journal article, 2020)Purpose: Although corticosteroids are frequently used in patients with advanced cancer, few studies have examined the impact of these drugs on patient-reported sleep. We aimed to examine the short-term impact of ... -
The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer
Paulsen, Ørnulf; Laird, Barry J; Aass, Nina Kathrine; Lea, Tor Erling; Fayers, Peter; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2017)Background Systemic inflammation is associated with reduced quality of life and increased symptoms in patients with advanced cancer. The aims of this study were to examine the relationships between inflammatory biomarkers ... -
Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer-a double-blind, randomized placebo-controlled clinical multicenter phase IV trial
Jakobsen, Gunnhild; Sjue, Karin; Paulsen, Ørnulf; Kaasa, Stein; Hjermstad, Marianne Jensen; Klepstad, Pål (Peer reviewed; Journal article, 2022)Purpose: Insomnia is frequent in patients with advanced cancer, and a variety of pharmacological agents is used to treat this condition. Still, few clinical trials have investigated the effectiveness of pharmacological ... -
Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer: study protocol for a double-blind, randomized, placebo-controlled, clinical multicenter trial
Jakobsen, Gunnhild; Engstrøm, Morten; Paulsen, Ørnulf; Sjue, Karin; Raj, Sunil Xavier; Thronæs, Morten; Hjermstad, Marianne Jensen; Kaasa, Stein; Fayers, Peter; Klepstad, Pål (Journal article; Peer reviewed, 2018)Background Despite the high prevalence of insomnia in patients with advanced cancer, there are no randomized controlled trials on pharmacological interventions for insomnia in this group of patients. A variety of ...