Browsing NTNU Open by Author "Opdahl, Signe"
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The association of women’s birth size with risk of molecular breast cancer subtypes: a cohort study
Sandvei, Marie Søfteland; Opdahl, Signe; Valla, Marit; Lagiou, Pagona; Vesterfjell, Ellen Veronika; Rise, Tor Vikan; Overrein, Tina Syvertsen; Skjervold, Anette Hansen; Engstrøm, Monica J; Bofin, Anna M.; Vatten, Lars J. (Peer reviewed; Journal article, 2021)Background: Because birth size appears to be positively associated with breast cancer risk, we have studied whether this risk may differ according to molecular breast cancer subtypes. Methods: A cohort of 22,931 women born ... -
Betydning av snusbruk for fertilitet hos par som tilbys assistert befruktning.
Stensen, Frida bakken (Master thesis, 2022)Sammendrag Problemstilling: Denne masteroppgaven er en observasjonsstudie, og en del av en prospektiv observasjonsstudie «Effekt av snus på fruktbarhet» av Stevanovic, som pågår ved Fertilitetsseksjonen, St Olavs hospital ... -
Birth size after embryo cryopreservation: larger by all measures?
Landsverk, Eirik; Westvik-Johari, Kjersti; Romundstad, Liv Bente Bergem; Opdahl, Signe (Peer reviewed; Journal article, 2023)STUDY QUESTION Are the changes in birthweight after frozen and fresh embryo transfer associated with corresponding changes in other measures of foetal growth and placental efficiency? SUMMARY ANSWER Although placental ... -
Cancer in children born after frozen-thawed embryo transfer: A cohort study
Sargisian, Nona; Lannering, Birgitta; Petzold, Max; Opdahl, Signe; Gissler, Mika; Pinborg, Anja; Henningsen, Anna-Karina Aaris; Tiitinen, Aila; Romundstad, Liv Bente Bergem; Spangmose, Anne Lærke; Bergh, Christina; Wennerholm, Ulla-Britt (Journal article; Peer reviewed, 2022) -
Cardiovascular disease, obesity, and type 2 diabetes in children born after assisted reproductive technology: A population-based cohort study
Norrman, Emma; Petzold, Max; Gissler, Mika; Spangmose, Anne Lærke; Opdahl, Signe; Henningsen, Anna-Karina; Pinborg, Anja; Tiitinen, Aila; Rosengren, Annika; Romundstad, Liv Bente; Wennerholm, Ulla-Britt; Bergh, Christina (Peer reviewed; Journal article, 2021)Background Some earlier studies have found indications of significant changes in cardiometabolic risk factors in children born after assisted reproductive technology (ART). Most of these studies are based on small cohorts ... -
The challenges of selective fertility and carryover effects in within-sibship analyses: the effect of assisted reproductive technology on perinatal mortality as an example
Westvik-Johari, Kjersti; Håberg, Siri Eldevik; Lawlor, Deborah A.; Romundstad, Liv Bente Bergem; Bergh, Christina; Wennerholm, Ulla-Britt; Gissler, Mika; Henningsen, Anna-Karina A.; Tiitinen, Aila; Pinborg, Anja; Opdahl, Signe (Peer reviewed; Journal article, 2023)Background Within-sibship analyses show lower perinatal mortality after assisted reproductive technology (ART) compared with natural conception (NC), a finding that appears biologically unlikely. We investigated whether ... -
Characterization of FGD5 expression in primary breast cancers and lymph node metastases
Valla, Marit; Mjønes, Patricia; Engstrøm, Monica J; Ytterhus, Borgny; Bordin, Diana Lilian; van Loon, Barbara; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Journal article; Peer reviewed, 2018)Faciogenital dysplasia 5 (FGD5) amplification drives tumor cell proliferation, and is present in 9.5% of breast cancers. We describe FGD5 expression, assess associations between FGD5 amplification and FGD5 expression, and ... -
Complications in pregnancies after assisted reproduction
Petersen, Sindre Hoff (Doctoral theses at NTNU;2023:161, Doctoral thesis, 2023)Sammendrag In vitro fertilisering (IVF), også kjent som prøverørsbefruktning eller assistert befruktning, er metoder for å oppnå svangerskap hos par og kvinner som ikke lykkes med å bli gravide på egenhånd. Det første ... -
Data resource profile: the Committee of Nordic Assisted Reproductive Technology and Safety (CoNARTaS) cohort
Opdahl, Signe; Henningsen, Anna-Karina Aaris; Bergh, Christina; Gissler, Mika; Romundstad, Liv Bente Bergem; Petzold, Max; Tiitinen, Aila; Wennerholm, Ulla-Britt; Pinborg, Anja (Journal article; Peer reviewed, 2019) -
DTX3 copy number increase in breast cancer: a study of associations to molecular subtype, proliferation and prognosis
Valla, Marit; Opdahl, Signe; Ytterhus, Borgny; Bofin, Anna M. (Journal article; Peer reviewed, 2021)Purpose The degree of cell proliferation is important for subclassifcation of breast cancers into prognostic and therapeutic groups. DTX3 has been identifed as a driver of proliferation in luminal breast cancer. In this ... -
Effect of Paternal Age on Reproductive Outcome in Assisted Reproductive Technology Compared to Spontanous Conception
Evensen, Mari; Kvalheim, Stine (Master thesis, 2016)Studies investigating the role of increasing paternal age for neonatal health in pregnancies following assisted reproductive technology (ART) are limited. In this large cohort study, we evaluated the association between ... -
FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis
Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Journal article; Peer reviewed, 2017)Purpose Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ... -
Gestational age and the risk of autism spectrum disorder in Sweden, Finland, and Norway: A cohort study
Risnes, Kari; Opdahl, Signe (Peer reviewed; Journal article, 2020)Introduction The complex etiology of autism spectrum disorder (ASD) is still unresolved. Preterm birth (<37 weeks of gestation) and its complications are the leading cause of death of babies in the world, and those who ... -
Gestational age at birth and hospitalisations for infections among individuals aged 0–50 years in Norway: a longitudinal, register-based, cohort study
Nilsen, Sara Marie; Valand, Jonas; Rogne, Tormod; Asheim, Andreas; Yin, Weiyao; Metsälä, Johanna; Opdahl, Signe; Døllner, Henrik; Damås, Jan Kristian; Kajantie, Eero; Solligård, Erik; Sandin, Sven; Risnes, Kari Ravndal (Peer reviewed; Journal article, 2023)Background Preterm birth is associated with increased risk of childhood infections. Whether this risk persists into adulthood is unknown and limited information is available on risk patterns across the full range of ... -
Growth in children conceived by ART
Magnus, Maria Christine; Wilcox, Allen J.; Fadum, Elin Anita; Gjessing, Håkon; Opdahl, Signe; Juliusson, Petur Benedikt; Romundstad, Liv Bente; Håberg, Siri Eldevik (Peer reviewed; Journal article, 2021)STUDY QUESTION: Is the growth pattern of children conceived by ART different compared to naturally conceived children. SUMMARY ANSWER: Both ART and underlying parental subfertility may contribute to differences in early ... -
Helse hos hjemmeboende eldre i Trøndelag i 2019
Karlsen, Håvard Rudi; Moa, Pål Fossland; Opdahl, Signe; Sliper, Jon Olav; Rangul, Vegard; Krokstad, Steinar; Eiksund, Sveinung Øystein; Molden, Thomas Hugaas; Jensberg, Heidi; Kvistad, Kyrre; Sund, Erik Reidar (Research report, 2024)Bakgrunn: Vi lever stadig lengre og økningen i levealder skyldes stadig bedre levekår, gunstige livsstiler, sosiale forbindelser og god medisinsk behandling. Utviklingen i levealder medfører at det blir stadig flere eldre. ... -
Interpreting Breast Cancer Mortality Trends Related to Introduction of Mammography Screening: A Simulation Study
Heggland, Torunn; Vatten, Lars Johan; Opdahl, Signe; Weedon-Fekjær, Harald (Peer reviewed; Journal article, 2022)Background. Several studies have evaluated the effect of mammography screening on breast cancer mortality based on overall breast cancer mortality trends, with varied conclusions. The statistical power of such trend analyses ... -
Invasive lobular breast cancer: The prognostic impact of histopathological grade, E-cadherin and molecular subtypes
Engstrøm, Monica J; Opdahl, Signe; Vatten, Lars Johan; Haugen, Olav Anton; Bofin, Anna M. (Peer reviewed; Journal article, 2015)Aims The aim of this study was to compare breast cancer specific survival (BCSS) for invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC) and, further, to evaluate critically the prognostic value of ... -
Long term trends of breast cancer incidence according to proliferation status
Klæstad, Elise; Opdahl, Signe; Raj, Sunil Xavier; Valla, Marit; Bofin, Anna M. (Peer reviewed; Journal article, 2022)Background Long-term breast cancer incidence trends according to proliferation status are poorly described. We studied time-trends in breast cancer incidence, using mitotic count and Ki-67 as markers of proliferation. ... -
Menopausal hormone therapy and breast cancer risk: effect modification by body mass through life
Sandvei, Marie Søfteland; Vatten, Lars Johan; Bjelland, Elisabeth Krefting; Eskild, Anne; Hofvind, Solveig; Ursin, Giske; Opdahl, Signe (Journal article; Peer reviewed, 2018)It is not known whether increased breast cancer risk caused by menopausal hormone therapy (HT) depends on body mass patterns through life. In a prospective study of 483,241 Norwegian women aged 50–69 years at baseline, ...