Blar i NTNU Open på forfatter "Omholt, Stig W"

Viser treff 1-6 av 6

    • A computational pipeline for quantification of mouse myocardial stiffness parameters 

      Nordbø, Øyvind; Lamata, P.; Land, Sander; Niederer, Steven A.; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Martens, Harald; Gjuvsland, Arne Bjørke; Tøndel, Kristin; Torp, Hans; Lohezic, M; Schneider, Jürgen; Remme, Espen W.; Smith, Nicolas P; Omholt, Stig W; Vik, Jon Olav (Journal article; Peer reviewed, 2014)
      The mouse is an important model for theoretical–experimental cardiac research, and biophysically based whole organ models of the mouse heart are now within reach. However, the passive material properties of mouse myocardium ...

    • Ancient Evolutionary Trade-Offs between Yeast Ploidy States 

      Zörgö, Enikö Beatrix; Chwialkowska, Karolina; Gjuvsland, Arne Bjørke; Garre, Elena; Sunnerhagen, Per; Liti, Gianni; Blomberg, Anders; Omholt, Stig W; Warringer, Jonas (Journal article; Peer reviewed, 2013)
      The number of chromosome sets contained within the nucleus of eukaryotic organisms is a fundamental yet evolutionarily poorly characterized genetic variable of life. Here, we mapped the impact of ploidy on the mitotic ...

    • Arterial Stiffening Provides Sufficient Explanation for Primary Hypertension 

      Pettersen, Klas; Bugenhagen, Scott M.; Nauman, Javaid; Beard, Daniel A.; Omholt, Stig W (Journal article; Peer reviewed, 2014)
      Hypertension is one of the most common age-related chronic disorders, and by predisposing individuals for heart failure, stroke, and kidney disease, it is a major source of morbidity and mortality. Its etiology remains ...

    • Effect of regulatory architecture on broad versus narrow sense heritability 

      Wang, Yunpeng; Vik, Jon Olav; Omholt, Stig W; Gjuvsland, Arne Bjørke (Journal article; Peer reviewed, 2013)
      Additive genetic variance (VA) and total genetic variance (VG) are core concepts in biomedical, evolutionary and production-biology genetics. What determines the large variation in reported VA/VG ratios from line-cross ...

    • Monotonicity is a key feature of genotype-phenotype maps 

      Gjuvsland, Arne Bjørke; Wang, Yunpeng; Plahte, Erik; Omholt, Stig W (Journal article; Peer reviewed, 2013)
      It was recently shown that monotone gene action, i.e., order-preservation between allele content and corresponding genotypic values in the mapping from genotypes to phenotypes, is a prerequisite for achieving a predictable ...

    • Propagation of genetic variation in gene regulatory networks 

      Plahte, Erik; Gjuvsland, Arne Bjørke; Omholt, Stig W (Journal article; Peer reviewed, 2013)
      A future quantitative genetics theory should link genetic variation to phenotypic variation in a causally cohesive way based on how genes actually work and interact. We provide a theoretical framework for predicting and ...