Browsing NTNU Open by Author "Olaisen, Camilla"
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Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress
Petrovic, Voin; Nepal, Anala; Olaisen, Camilla; Bachke, Siri; Hira, Jonathan; Søgaard, Caroline Krogh; Røst, Lisa Marie; Misund, Kristine; Andreassen, Trygve; Melø, Torun Margareta; Bartosova, Zdenka; Bruheim, Per; Otterlei, Marit (Journal article; Peer reviewed, 2018)The use of garlic and garlic-based extracts has been linked to decreased incidence of cancer in epidemiological studies. Here we examine the molecular and cellular activities of a simple homemade ethanol-based garlic extract ... -
Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel
Petrovic, Voin; Olaisen, Camilla; Sharma, Animesh; Nepal, Anala; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge; Slupphaug, Geir; Otterlei, Marit (Journal article; Peer reviewed, 2017)Cell extracts from A549, H460, and U2OS human cancer cell lines treated with cisplatin and docetaxel were analyzed by mass spectrometry (MS) proteomic analysis. The extracts were enriched for cellular signaling proteins ... -
Cytosolic scaffold functions of PCNA
Olaisen, Camilla (Doctoral theses at NTNU;2017:203, Doctoral thesis, 2017)PCNA som et plattform-protein i cytosol Kroppen vår består av millioner av celler som alle stammer fra en enkelt celle. For hver celledeling må arvestoffet, DNA-et, kopieres feilfritt i et samarbeid mellom mange ulike ... -
Incidence of invasive infections with Group B streptococcus in adults in Norway 1996–2019: a nationwide registry-based case–control study
Uggen, Elise; Olaisen, Camilla; Lyng, Randi Valsø; Simonsen, Gunnar Skov; Bævre-Jensen, Roar Magne; Gran, Frode Width; Åsvold, Bjørn Olav; Nilsen, Tom Ivar Lund; Damås, Jan Kristian; Afset, Jan Egil (Journal article; Peer reviewed, 2024)Purpose Group B streptococcus (GBS) colonizes the gastrointestinal and vaginal mucosa in healthy adults, but has also become an increasing cause of invasive infection. The aims of this study were to describe the incidence ... -
Metodeutvikling og validering av real-time PCR for deteksjon av bac gen hos Streptococcus agalactiae
Amundsen, Marte Myhr; Edvardsen, Maren-Helene Hafslund (Bachelor thesis, 2022)Streptococcus agalactiae omtales ofte som gruppe B streptokokker (GBS) og er en av de vanligste årsakene til infeksjonssykdom hos nyfødte. Ved Nasjonalt referanselaboratorium for GBS ved St.Olavs Hospital overvåkes serotyper ... -
The Streptococcus agalactiae R3 surface protein is encoded by sar5
Basson, Adelle; Olaisen, Camilla; Selvik, Linn-Karina M.; Lyng, Randi Valsø; Lysvand, Hilde; Gidon, Alexandre; Ås, Christina Gabrielsen; Afset, Jan Egil; Dragset, Marte Singsås (Peer reviewed; Journal article, 2022)Streptococcus agalactiae (group B streptococcus; GBS) is an important human pathogen causing pneumonia, sepsis and meningitis in neonates, as well as infections in pregnant women, immunocompromised individuals, and the ... -
The role of PCNA as a scaffold protein in cellular signaling is functionally conserved between yeast and humans
Olaisen, Camilla; Kvitvang, Hans Fredrik Nyvold; Lee, Sungmin; Almaas, Eivind; Bruheim, Per; Drabløs, Finn; Otterlei, Marit (Journal article; Peer reviewed, 2018)Proliferating cell nuclear antigen (PCNA), a member of the highly conserved DNA sliding clamp family, is an essential protein for cellular processes including DNA replication and repair. A large number of proteins from ... -
Uracil DNA Glycosylase UNG2 carrying the germline mutation Arg88Cys: Potential implications for adaptive immunity and cancer
Olaisen, Camilla (Master thesis, 2011)Uracil is normally found in RNA where it replaces the DNA base thymine. However, it can occur in DNA if misincorporated in place of thymine, or as a result of deamination of cytosine. Uracil is also a normal intermediate ...