Browsing NTNU Open by Author "Nyström, Sofie"

Now showing items 1-8 of 8

    • Insulin amyloid polymorphs: implications for iatrogenic cytotoxicity† 

      Yuzu, Keisuke; Lindgren, Mikael; Nyström, Sofie; Zhang, Jun; Mori, Wakako; Kunitomi, Risako; Nagase, Terumasa; Iwaya, Keiichi; Hammarström, Per; Zako, Tamotsu (Peer reviewed; Journal article, 2020)
      Amyloid specific fluorescent probes are becoming an important tool for studies of disease progression and conformational polymorphisms in diseases related to protein misfolding and aggregation such as localized and systemic ...

    • Nanoscale Structure and Spectroscopic Probing of Aβ1-40 Fibril Bundle Formation 

      Psonka-Antonczyk, Katarzyna Maria; Hammarström, Per; Johansson, Leif B. G.; Lindgren, Mikael; Stokke, Bjørn Torger; Nilsson, K. Peter R.; Nyström, Sofie (Peer reviewed; Journal article, 2016)
      Amyloid plaques composed of fibrillar Amyloid-β (Aβ) are hallmarks of Alzheimer's disease. However, Aβ fibrils are morphologically heterogeneous. Conformation sensitive luminescent conjugated oligothiophenes (LCOs) are ...

    • Nanoscopic and Photonic Ultrastructural Characterization of Two Distinct Insulin Amyloid States 

      Psonka-Antonczyk, Katarzyna Maria; Duboisset, Julien; Stokke, Bjørn Torger; Zako, Tamotsu; Kobayashi, Takahiro; Maeda, Mizuo; Nyström, Sofie; Mason, Jeffrey; Hammarström, Per; Nilsson, K. Peter R.; Lindgren, Mikael (Journal article; Peer reviewed, 2012)
      Two different conformational isoforms or amyloid strains of insulin with different cytotoxic capacity have been described previously. Herein these filamentous and fibrillar amyloid states of insulin were investigated using ...

    • Social License to Automate. Emerging Approaches to Demand Side Management 

      Adams, Sophie; Diamond, Lisa; Esterl, Tara; Fröhlich, Peter; Ghotge, Rishabh; Hemm, Regina; Henriksen, Ida Marie; Katzeff, Cecilia; Kuch, Declan; Lancelot Michellod, Julien; Lukszo, Zofia; Nijssen, Koen; Nyström, Sofie; Ryghaug, Marianne; Winzer, Christian; Yilmaz, Selin (Research report, 2021)

    • Social License to Automate.Executive Summary. Emerging Approaches to Demand Side Management 

      Adams, Sophie; Diamond, Lisa; Esterl, Tara; Fröhlich, Peter; Ghotge, Rishabh; Hemm, Regina; Henriksen, Ida Marie; Katzeff, Cecilia; Kuch, Declan; Lancelot Michellod, Julien; Lukszo, Zofia; Nijssen, Koen; Nyström, Sofie; Ryghaug, Marianne; Winzer, Christian; Yilmaz, Selin (Research report, 2021)

    • Spectral correlation analysis of Amyloid beta plaque inhomogeneity from double staining experiments 

      Ellingsen, Pål Gunnar; Nyström, Sofie; Reitan, Nina Kristine; Lindgren, Mikael (Journal article; Peer reviewed, 2013)
      A spectral correlation algorithm for the analysis of hyperspectral fluorescence images is proposed by Ellingsen et al. [J. Biomed. Opt. 18, 020501 (2013)]. Here, it is applied to the analysis of double-stained Aβ amyloid ...

    • trans-Stilbenoids with Extended Fluorescence Lifetimes for the Characterization of Amyloid Fibrils 

      Zhang, Jun; Sandberg, Alexander; Wu, Xiongyu; Nyström, Sofie; Lindgren, Mikael; Konradsson, Peter; Hammarström, Per (Journal article; Peer reviewed, 2017)
      It was previously reported that two naphthyl-based trans-stilbene probes, (E)-4-(2-(naphthalen-1-yl)vinyl)benzene-1,2-diol (1) and (E)-4-(2-(naphthalen-2-yl)vinyl)benzene-1,2-diol (3), can bind to both native transthyretin ...

    • Tyrosine Side-Chain Functionalities at Distinct Positions Determine the Chirooptical Properties and Supramolecular Structures of Pentameric Oligothiophenes 

      Bäck, Marcus; Selegård, Robert; Todarwal, Yogesh; Nyström, Sofie; Norman, Patrick; Linares, Mathieu; Hammarström, Per; Lindgren, Mikael; Nilsson, K. Peter R. (Peer reviewed; Journal article, 2020)
      Control over the photophysical properties and molecular organization of π-conjugated oligothiophenes is essential to their use in organic electronics. Herein we synthesized and characterized a variety of anionic pentameric ...