Browsing NTNU Open by Author "Nilsson, Lars"

Now showing items 1-3 of 3

    • Contrast Enhanced Magnetic Resonance Imaging of Amyloid-β Plaques in a Murine Alzheimer's Disease Model 

      Sulheim, Einar; Widerøe, Marius; Bäck, Marcus; Nilsson, K Peter R; Hammarström, Per; Nilsson, Lars; Davies, Catharina de Lange; Åslund, Karl Olof Andreas (Journal article; Peer reviewed, 2023)
      Background: Early detection of amyloid-β (Aβ) aggregates is a critical step to improve the treatment of Alzheimer’s disease (AD) because neuronal damage by the Aβ aggregates occurs before clinical symptoms are apparent. ...

    • Glial activation and inflammation along the Alzheimer's disease continuum 

      Nordengen, Kaja; Kirsebom, Bjørn-Eivind; Henjum, Kristi; Selnes, Per; Gisladottir, Berglind; Wettergreen, Marianne; Torsetnes, Silje Bøen; Grøntvedt, Gøril Rolfseng; Waterloo, Knut; Aarsland, Dag; Nilsson, Lars; Fladby, Tormod (Journal article; Peer reviewed, 2019)
      Background Neuronal and glial cell interaction is essential for synaptic homeostasis and may be affected in Alzheimer’s disease (AD). We measured cerebrospinal fluid (CSF) neuronal and glia markers along the AD continuum, ...

    • Impaired astrocytic Ca2+ signaling in awake-behaving Alzheimer’s disease transgenic mice 

      Åbjørsbråten, Knut Sindre; Skaaraas, Gry HE Syverstad; Cunen, Celine Marie Løken; Bjørnstad, Daniel Marelius; Binder, Kristin M Gullestad; Bojarskaite, Laura; Jensen, Vidar; Nilsson, Lars; Rao, Shreyas B.; Tang, Wannan; Hermansen, Gudmund Horn; Nagelhus, Erlend Arnulf; Ottersen, Ole Petter; Torp, Reidun; Enger, Rune (Peer reviewed; Journal article, 2022)
      Increased astrocytic Ca2+ signaling has been shown in Alzheimer’s disease mouse models, but to date no reports have characterized behaviorally induced astrocytic Ca2+ signaling in such mice. Here, we employ an event-based ...