Blar i NTNU Open på forfatter "Nilsen, Turid"

Viser treff 1-4 av 4

    • Naloksonnesespray – biotilgjengelighet og opptaksmønster i en fase 1-studie 

      Tylleskär, Ida; Skulberg, Arne Kristian; Nilsen, Turid; Skarra, Sissel; Dale, Ola (Journal article; Peer reviewed, 2019)
      Kameratredning med nalokson i nesespray kan forebygge dødsfall ved opioidoverdoser. For å få best mulig opptak av nalokson i nesen må sprayen gis med et lavt volum med høy medikamentkonsentrasjon. Målet med studien var å ...

    • Pharmacodynamics and arteriovenous difference of intravenous naloxone in healthy volunteers exposed to remifentanil 

      Tylleskär, Ida; Skulberg, Arne Kristian; Skarra, Sissel; Nilsen, Turid; Dale, Ola (Journal article; Peer reviewed, 2018)
      Purpose Pharmacodynamic studies of naloxone require opioid agonism. Steady state condition may be achieved by remifentanil TCI (target controlled infusion). Opioid agonism can be measured by pupillometry. It is not known ...

    • Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: an explorative study in healthy volunteers 

      Skulberg, Arne Kristian; Tylleskär, Ida; Nilsen, Turid; Skarra, Sissel; Salvesen, Øyvind; Sand, Trond; Loftsson, Thorsteinn; Dale, Ola (Journal article; Peer reviewed, 2018)
      Purpose This study aimed to develop a model for pharmacodynamic and pharmacokinetic studies of naloxone antagonism under steady-state opioid agonism and to compare a high-concentration/low-volume intranasal naloxone ...

    • Pharmacokinetics of a new, nasal formulation of naloxone 

      Tylleskär, Ida; Skulberg, Arne Kristian; Nilsen, Turid; Skarra, Sissel; Jansook, Phatsawee; Dale, Ola (Journal article; Peer reviewed, 2017)
      Purpose Nasal naloxone is wanted for bystander administration in opioid overdose and as a needle-free alternative for emergency medical personnel. Epidemiologic studies have indicated a therapeutic effect of bystander ...