Browsing NTNU Open by Author "Nilsen, Kristian Bernhard"

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    • A tonic heat test stimulus yields a larger and more reliable conditioned pain modulation effect compared to a phasic heat test stimulus 

      Lie, Marie; Matre, Dagfinn; Hansson, Per; Stubhaug, Audun; Zwart, John-Anker; Nilsen, Kristian Bernhard (Journal article; Peer reviewed, 2017)
      Introduction: The interest in conditioned pain modulation (CPM) as a clinical tool for measuring endogenously induced analgesia is increasing. There is, however, large variation in the CPM methodology, hindering comparison ...

    • Accuracy of neuropathic pain measurements in patients with symptoms of polyneuropathy: validation of painDETECT, Self-Completed Leeds Assessment of Neuropathic Symptoms and Signs, and Douleur Neuropathique 4 

      Dunker, Øystein; Grotle, Margreth; Kvaløy, Marie Bu; Uglem, Martin; Løseth, Sissel; Hjelland, Ina Elen; Kleggetveit, Inge Petter; Allen, Sara Maria; Vigeland, Maria Dehli; Killingmo, Rikke Munk; Sand, Trond; Nilsen, Kristian Bernhard (Peer reviewed; Journal article, 2022)
      Pain is a common symptom in patients referred to polyneuropathy assessment. Diagnostic evaluation and choice of treatment may depend on whether the pain is likely to be neuropathic or not. This study aimed to investigate ...

    • The association between insomnia, c-reactive protein, and chronic low back pain: Cross-sectional analysis of the HUNT study, Norway 

      Ho, Kevin Kwan Ngai; Simic, Milena; Småstuen, Milada Cvancarova; de Barros Pinheiro, Marina; Ferreira, Paulo Herrique; Johnsen, Marianne Bakke; Heuch, Ingrid; Grotle, Margreth; Zwart, John-Anker; Nilsen, Kristian Bernhard (Peer reviewed; Journal article, 2019)
      Chronic low back pain (chronic LBP) is the number one cause for years lived with disability among 301 diseases and injuries analyzed by The Global Burden of Disease study 2013. Insomnia is highly prevalent among people ...

    • Autonomic activation and muscle activity in relation to musculoskeletal pain 

      Nilsen, Kristian Bernhard (Doktoravhandlinger ved NTNU, 1503-8181; 2007:202, Doctoral thesis, 2007)
      Background and objectives: Musculoskeletal pain is frequent and the most common cause of sick leave in Norway. Although chronic musculoskeletal pain is conceived to be related to social or mental stress, the mechanism for ...

    • Autonomic and muscular responses and recovery to one-hour laboratory mental stress in healthy subjects 

      Nilsen, Kristian Bernhard; Sand, Trond; Stovner, Lars Jacob; Leistad, Rune Bang; Westgaard, Rolf Harald (Journal article; Peer reviewed, 2007-08-14)
      Background: Stress is a risk factor for musculoskeletal pain. We wanted to explore stress related physiology in healthy subjects in order to gain insight into mechanisms of pain development which may relate to the ...

    • A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain 

      Ho, Kevin Kwan Ngai; Skarpsno, Eivind S.; Nilsen, Kristian Bernhard; Ferreira, Paulo Herrique; Pinheiro, Marina; Hopstock, Laila Arnesdatter; Johnsen, Marianne Bakke; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Stubhaug, Audun; Simic, Milena (Peer reviewed; Journal article, 2022)
      Objectives - To examine the possible bidirectional association between insomnia and comorbid chronic low back pain (LBP) and lower limb pain and to explore whether high-sensitivity C-reactive protein (hsCRP) amplifies these ...

    • A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain 

      Ho, Kevin Kwan Ngai; Skarpsno, Eivind S.; Nilsen, Kristian Bernhard; Ferreira, Paulo Herrique; Pinheiro, Marina; Hopstock, Laila Arnesdatter; Johnsen, Marianne Bakke; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Stubhaug, Audun; Simic, Milena (Journal article; Peer reviewed, 2022)

    • Cardiovascular responses to cognitive stress in patients with migraine and tension-type headache 

      Leistad, Rune Bang; Sand, Trond; Nilsen, Kristian Bernhard; Westgaard, Rolf Harald; Stovner, Lars Jacob (Journal article; Peer reviewed, 2007)
      Background: The purpose of this study was to investigate the temporal relationship between autonomic changes and pain activation in migraine and tension-type headache induced by stress in a model relevant for everyday ...

    • Changes in quality of life in individuals with narcolepsy type 1 after the H1N1-influenza epidemic and vaccination campaign in Norway: a two-year prospective cohort study 

      Nordstrand, Sebjørg Elizabeth Hesla; Hansen, Berit M Hjelde; Kamaleri, Yusman; Nilsen, Kristian Bernhard; Rootwelt-Revheim, Terje; Karlsen, Tor-Ivar; Knudsen, Stine (Journal article; Peer reviewed, 2018)
      Objective Cross-sectional studies show a lower health-related quality of life (HRQoL) in individuals with narcolepsy. We aimed to describe changes in HRQoL after two years of multidisciplinary follow-up in a cohort of ...

    • Clinical and vascular responses to propranolol and candesartan in migraine patients: A randomized controlled clinical trial 

      Barzenje, Aros D; Gjesdal, Knut; Winsvold, Bendik K S; Småstuen, Milada Cvancarova; Stovner, Lars Jacob; Gravdahl, Gøril Bruvik; Nilsen, Kristian Bernhard (Journal article, 2020)
      Background: Both propranolol and candesartan are prophylactic drugs for migraine, but with unknown mechanisms of action. The objectives of the present study were to investigate these drugs’ effects on arterial wall dynamics ...

    • Cognitive event-related potentials during the sub-acute phase of severe traumatic brain injury and their relationship to outcome 

      Hauger, Solveig Lægreid; Olafsen, Kjell; Schnakers, Caroline; Andelic, Nada; Nilsen, Kristian Bernhard; Helseth, Eirik; Funderud, Ingrid; Andersson, Stein; Schanke, Anne-Kristine; Løvstad, Marianne (Journal article; Peer reviewed, 2017)
      Predicting outcome in the early phase after severe traumatic brain injury (sTBI) is a major clinical challenge, particularly identifying patients with potential for good cognitive outcome.The current single-center prospective ...

    • COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study 

      Jacobsen, Kaya Kvarme; Børte, Sigrid; Laborie, Lene Bjerke; Kristiansen, Hege; Schäfer, Annette; Gundersen, Trude; Zayats, Tetyana; Winsvold, Bendik Kristoffer Slagsvold; Karen, Rosendahl; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Fors, Egil Andreas; Kristoffersen, Espen Saxhaug; Heuch, Ingrid; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Nielsen, Jonas B.; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars G; Thomas, Laurent Francois; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Lie, Marie U.; Stensland, Synne; Zhou, Wei (Peer reviewed; Journal article, 2023)
      Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30% of all total hip arthroplasties (THAs) in adults ...

    • Diagnostic accuracy of the 5.07 monofilament test for diabetes polyneuropathy: influence of age, sex, neuropathic pain and neuropathy severity 

      Dunker, Øystein; Uglem, Martin; Kvaløy, Marie Bu; Løseth, Sissel; Hjelland, Ina Elen; Allen, Sara Maria; Vigeland, Maria Dehli; Kleggetveit, Inge Petter; Sand, Trond Halfdan; Nilsen, Kristian Bernhard (Peer reviewed; Journal article, 2023)
      Introduction There is a need for simple and cheap diagnostic tools for diabetic polyneuropathy (DPN). We aimed to assess the diagnostic accuracy of the 5.07/10 g monofilament test in patients referred to polyneuropathy ...

    • Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools 

      Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik K S; O'Connell, Kevin S; Frei, Oleksandr; Shadrin, Alexey; Cheng, Weiqiu; Bettella, Francesco; Rødevand, Linn; Ødegaard, Ketil Joachim; Fan, Chun C; Pirinen, Matti J; Hautakangas, Heidi M; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Tronvik, Erling Andreas; Kristoffersen, Espen Saxhaug; Zwart, John Anker Henrik; Nielsen, Jonas Bille; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Stovner, Lars Jacob; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir Lingaas; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole (Peer reviewed; Journal article, 2022)
      Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are ...

    • Does insomnia modify the association between C-reactive protein and migraine? The Tromsø Study 2015-2016. 

      Hagen, Knut; Hopstock, Laila Arnesdatter; Eggen, Anne Elise; Mathiesen, Ellisiv B.; Nilsen, Kristian Bernhard (Journal article; Peer reviewed, 2019)
      Background The relationship between high sensitivity C-reactive protein and migraine is unclear. The aim of this cross-sectional population-based study was to investigate the association between high sensitivity C-reactive ...

    • Does pain sensitivity change by migraine phase? A blinded longitudinal study 

      Hagen, Knut; Omland, Petter Moe; Stovner, Lars Jacob; Sand, Trond Halfdan; Uglem, Martin; Tronvik, Erling Andreas; Nilsen, Kristian Bernhard; Linde, Anders Mattias (Journal article; Peer reviewed, 2016)
      Objective: Studies suggest that pain thresholds may be altered before and during migraine headaches, but it is still debated if a central or peripheral dysfunction is responsible for the onset of pain in migraine. The ...

    • Experimental sleep restriction increases latency jitter in pain elicited cortical responses 

      Hansen, Johannes Orvin; Omland, Petter Moe; Nilsen, Kristian Bernhard; Sand, Trond; Matre, Dagfinn (Peer reviewed; Journal article, 2021)
      Objective Previous studies have shown increased pain scores to painful stimulation after experimental sleep restriction, but reduced or unchanged magnitude of the event related potentials (ERPs) when averaged in the ...

    • Fatigue and cognition: Pupillary responses to problem-solving in early multiple sclerosis patients 

      de Rodez Benavent, Sigrid Aune; Nygaard, Gro Owren; Harbo, Hanne; Tønnesen, Siren; Sowa, Piotr; Landrø, Nils Inge; Gustavsen, Marte Wendel; Etholm, Lars; Nilsen, Kristian Bernhard; Drolsum, Liv; Kerty, Emilia; Celius, Elisabeth Gulowsen; Laeng, Bruno (Journal article; Peer reviewed, 2017)
      Introduction In early multiple sclerosis (MS) patients, cognitive changes and fatigue are frequent and troublesome symptoms, probably related to both structural and functional brain changes. Whether there is a common ...

    • Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions 

      Khoury, Samar; Parisien, Marc; Thompson, Scott J.; Vachon-Presseau, Etienne; Roy, Mathieu; Mitchell, Amy; Winsvold, Bendik K S; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J.; Fors, Egil Andreas; Heuch, Ingrid; Nielsen, Jonas Bille; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Kania, Artur; Mogil, Jeffrey S.; Diatchenko, Luda (Peer reviewed; Journal article, 2021)
      Chronic pain is often present at more than one anatomical location, leading to chronic overlapping pain conditions (COPC). Whether COPC represents a distinct pathophysiology from the occurrence of pain at only one site is ...

    • Impact of technical variations on the ring-finger test for carpal tunnelsyndrome 

      Schulze, Daniel Gregor; Nordby, Karl-Christian; Småstuen, Milada Cvancarova; Clemm, Thomas; Grotle, Margreth; Zwart, John-Anker; Nilsen, Kristian Bernhard (Journal article; Peer reviewed, 2019)
      Objective To assess if recording the sensory latencies of the median and ulnar nerves one-by-one (consecutive) or at the same time (simultaneous) in the ring-finger test for carpal tunnel syndrome (CTS) will show equivalent ...