Blar i NTNU Open på forfatter "Neckmann, Ulrike"

Viser treff 1-7 av 7

    • A massive parallel sequencing workflow for diagnostic genetic testing of mismatch repair genes 

      Hansen, Maren Fridtjofsen; Neckmann, Ulrike; Lavik, Liss Anne; Vold, Trine; Gilde, Bodil; Toft, Ragnhild Karlgård; Sjursen, Wenche (Journal article; Peer reviewed, 2014)
      The purpose of this study was to develop a massive parallel sequencing (MPS) workflow for diagnostic analysis of mismatch repair (MMR) genes using the GS Junior system (Roche). A pathogenic variant in one of four MMR genes, ...

    • GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients 

      Neckmann, Ulrike; Wolowczyk, Camilla; Hall, Martina; Almaas, Eivind; Ren, Jiang; Zhao, Sen; Johannessen, Bjarne; Skotheim, Rolf I.; Bjørkøy, Geir; Dijke, Peter Ten; Holien, Toril (Journal article; Peer reviewed, 2019)
      Background In breast cancer, activation of bone morphogenetic protein (BMP) signaling and elevated levels of BMP-antagonists have been linked to tumor progression and metastasis. However, the simultaneous upregulation of ...

    • Heterogeneity within the 66cl4 cell line from the 4T1 model of metastatic breast cancer 

      Tran, Tuong Vy Thi (Master thesis, 2018)
      Breast cancer is one of the most common form of cancer among women globally and metastasis is the primary cause of death in breast cancer patients. In the past decades it has been increasingly known that tumors are ...

    • Massive parallel amplicon sequencing of the mismatch repair genes MSH2, MSH6, MLH1 and PMS2. Implementation of hereditary and non-hereditary subtypes of colorectal cancer 

      Neckmann, Ulrike (Master thesis, 2013)
       Colorectal cancer is the one of the most frequent malignancies and accounts for approximately 3500 new cases each year in Norway. Colorectal cancer is a heterogeneous disorder and can be divided into three main groups: ...

    • NRF2 drives an oxidative stress response predictive of breast cancer 

      Wolowczyk, Camilla; Neckmann, Ulrike; Aure, Miriam Ragle; Hall, Martina; Johannessen, Bjarne; Zhao, Sen; Skotheim, Rolf I.; Andersen, Sonja Benedikte; Zwiggelaar, Rosalie Theda Margien; Steigedal, Tonje S.; Lingjærde, Ole Christian; Sahlberg, Kristine Kleivi; Almaas, Eivind; Bjørkøy, Geir (Peer reviewed; Journal article, 2022)
      Many breast cancer patients are diagnosed with small, well-differentiated, hormone receptor-positive tumors. Risk of relapse is not easily identified in these patients, resulting in overtreatment. To identify metastasis-related ...

    • On the Identification of Features of Aggressive Breast Cancer Development 

      Neckmann, Ulrike (Doctoral theses at NTNU;2019:68, Doctoral thesis, 2019)
      Innføring av nasjonale mammografiprogrammer har ført til en økning av antall brystkrefttilfeller; først og fremst ikke-invasive tumorer. Vi vet at få av disse svulstene vil bli mestastatiske og dødelige, men vi mangler i ...

    • Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking 

      Sofias, Alexandros Marios; Toner, Yohana C.; Meerwaldt, Anu E.; van Leent, Mandy M. T.; Soultanidis, Georgios; Elschot, Mattijs; Gonai, Haruki; Grendstad, Kristin; Flobak, Åsmund; Neckmann, Ulrike; Wolowczyk, Camilla; Fisher, Elizabeth L.; Reiner, Thomas; Davies, Catharina de Lange; Bjørkøy, Geir; Teunissen, Abraham J. P.; Ochando, Jordi; Pérez-Medina, Carlos; Mulder, Willem J. M.; Hak, Sjoerd (Journal article; Peer reviewed, 2020)
      Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ...