• Adherence to clinical guidelines for Barrett’s esophagus 

      Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2019)
      Background and aim: Clinical guidelines recommend endoscopy surveillance at given intervals or endoscopic therapy for Barrett’s esophagus with low-grade dysplasia (LGD) and high-grade dysplasia (HGD). Whether these guidelines ...
    • Circulating Sex Hormone Levels and Risk of Esophageal Adenocarcinoma in a Prospective Study in Men 

      Xie, Shao-Hua; Ness-Jensen, Eivind; Rabbani, Sirus; Langseth, Hilde; Gislefoss, Randi Elin; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2019)
      OBJECTIVES: Sex hormones have been hypothesized to explain the strong male predominance in esophageal adenocarcinoma, but evidence is needed. This study examined how circulating sex hormone levels influence future risk of ...
    • Clinical prediction model for tumor progression in Barrett’s esophagus 

      Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2018)
      Background Individuals with Barrett’s esophagus (BE) are at increased risk of high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC), but the cost-effectiveness of general surveillance of BE is low. This study ...
    • Cohort profile: The Nordic Antireflux Surgery Cohort (NordASCo) 

      Maret-Ouda, John; Wahlin, Karl; Artama, Miia; Brusselaers, Nele; Färkkilä, Martti; Lynge, Elsebeth; Mattsson, Fredrik; Pukkala, Eero; Romundstad, Pål Richard; Tryggvadóttir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper (Journal article; Peer reviewed, 2017)
      Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having ...
    • Cohort profile: the Swedish Prescribed Drugs and Health Cohort (SPREDH) 

      Xie, Shao-Hua; Santoni, Giola; Mattsson, Fredrik; Ness-Jensen, Eivind; Lagergren, Jesper (Journal article; Peer reviewed, 2019)
      PURPOSE: The Swedish Prescribed Drugs and Health Cohort (SPREDH) is a Swedish population-based cohort based on data from four nationwide health data registers, created with the aim of investigating how the use of selected ...
    • Endoscopy for Gastroesophageal Reflux Disease and Survival in Esophageal Adenocarcinoma 

      Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Peer reviewed; Journal article, 2019)
      Gastroesophageal reflux disease (GERD) is a risk factor of esophageal adenocarcinoma (EAC) and the most common indication for upper gastrointestinal endoscopy. Yet, whether GERD or endoscopy practice influence survival in ...
    • Hypergastrinemia is associated with an increased risk of gastric adenocarcinoma with proximal location: A prospective population-based nested case-control study 

      Ness-Jensen, Eivind; Bringeland, Erling Audun; Mattsson, Fredrik; Mjønes, Patricia; Lagergren, Jesper; Grønbech, Jon Erik; Waldum, Helge; Fossmark, Reidar (Peer reviewed; Journal article, 2020)
      The incidence of proximal gastric adenocarcinoma is increasing among younger adults. Rodent models have shown that hypergastrinemia causes carcinogenesis in the proximal stomach. The aim of our study was therefore to assess ...
    • Prediagnostic circulating levels of sex hormones and survival in esophageal adenocarcinoma 

      Xie, Shao-hua; Ness-Jensen, Eivind; Langseth, Hilde; Gislefoss, Randi Elin; Mattsson, Fredrik; Lagergren, Jesper (Peer reviewed; Journal article, 2021)
      ex hormonal differences may contribute to the strong male predominance in esophageal adenocarcinoma (EAC), but whether sex hormone levels influence survival in EAC is unstudied. Our study aimed to assess associations between ...
    • Risk of gastric and oesophageal adenocarcinomas following discontinuation of long-term proton-pump inhibitor therapy 

      Holmberg, Dag; Mattsson, Fredrik; Xie, Shaohua; Ness-Jensen, Eivind; El-Serag, Hashem; Lagergren, Jesper (Peer reviewed; Journal article, 2022)
      Background There is uncertainty whether long-term use of proton-pump inhibitors can cause gastric adenocarcinoma (GAC) and oesophageal adenocarcinoma (OAC). This study aimed to determine how discontinuation of long-term ...