• Ancient acquisition of "alginate utilization loci" by human gut microbiota 

      Mathieu, Sophie; Touvrey-Loiodice, Melanie; Poulet, Laurent; Drouillard, Sophie; Vincentelli, Renaud; Henrissat, Bernard; Skjåk-Bræk, Gudmund; Helbert, William (Journal article; Peer reviewed, 2018)
      In bacteria from the phylum Bacteroidetes, the genes coding for enzymes involved in polysaccharide degradation are often colocalized and coregulated in so-called “polysaccharide utilization loci” (PULs). PULs dedicated to ...
    • Functional Exploration of the Polysaccharide Lyase Family PL6 

      Mathieu, Sophie; Henrissat, Bernard; Labre, Flavien; Skjåk-Bræk, Gudmund; Helbert, William (Journal article; Peer reviewed, 2016)
      Alginate, the main cell-wall polysaccharide of brown algae, is composed of two residues: mannuronic acid (M-residues) and, its C5-epimer, guluronic acid (G-residues). Alginate lyases define a class of enzymes that cleave ...