• Interplay of choline metabolites and genes in patient-derived breast cancer xenografts 

      Grinde, Maria Tunset; Skrbo, Nirma; Moestue, Siver Andreas; Rødland, Einar Andreas; Borgan, Eldrid; Kristian, Alexandr; Sitter, Beathe; Bathen, Tone; Børresen-Dale, Anne-Lise; Mælandsmo, Gunhild; Engebråten, Olav; Sørlie, Therese; Marangoni, Elisabetta; Gribbestad, Ingrid S (Journal article; Peer reviewed, 2014)
      Introduction Dysregulated choline metabolism is a well-known feature of breast cancer, but the underlying mechanisms are not fully understood. In this study, the metabolomic and transcriptomic characteristics of a large ...
    • Metabolic response to everolimus in patient-derived triple negative breast cancer xenografts 

      Euceda, Leslie R.; Hill, Deborah Katherine; Stokke, Endre; Hatem, Rana; Botty, Rania; Bieche, Ivan; Marangoni, Elisabetta; Bathen, Tone Frost; Moestue, Siver Andreas (Journal article; Peer reviewed, 2017)
      Patients with triple-negative breast cancer (TNBC) are unresponsive to endocrine and anti-HER2 pharmacotherapy, limiting their therapeutic options to chemotherapy. TNBC is frequently associated with abnormalities in the ...