Browsing NTNU Open by Author "Maleki, Susan"
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Alginate Biosynthesis Factories in Pseudomonas fluorescens : Localization and Correlation with Alginate Production Level
Maleki, Susan; Almaas, Eivind; Zotchev, Sergey; Valla, Svein; Ertesvåg, Helga (Journal article; Peer reviewed, 2016)Pseudomonas fluorescens is able to produce the medically and industrially important exopolysaccharide alginate. The proteins involved in alginate biosynthesis and secretion form a multiprotein complex spanning the inner ... -
Blood-borne extracellular vesicles of bacteria and intestinal cells in patients with psychotic disorders
Tunset, Mette Elise; Haslene-Hox, Hanne; Van Den Bossche, Tim; Maleki, Susan; Vaaler, Arne Einar; Kondziella, Daniel (Journal article; Peer reviewed, 2023)Background: Human cells and bacteria secrete extracellular vesicles (EV) which play a role in intercellular communication. EV from the host intestinal epithelium are involved in the regulation of bacterial gene expression ... -
Exploiting mannuronan C-5 epimerases in commercial alginate production
Tøndervik, Anne; Aarstad, Olav Andreas; Aune, Randi; Maleki, Susan; Rye, Philip D; Dessen, Arne; Skjåk-Bræk, Gudmund; Sletta, Håvard (Peer reviewed; Journal article, 2020)Alginates are one of the major polysaccharide constituents of marine brown algae in commercial manufacturing. However, the content and composition of alginates differ according to the distinct parts of these macroalgae and ... -
Identification of a New Phosphatase Enzyme Potentially Involved in the Sugar Phosphate Stress Response in Pseudomonas fluorescens
Maleki, Susan; Hrudikova, Radka; Zotchev, Sergey; Ertesvåg, Helga (Journal article; Peer reviewed, 2017)The alginate-producing bacterium Pseudomonas fluorescens utilizes the Entner-Doudoroff (ED) and pentose phosphate (PP) pathways to metabolize fructose, since the upper part of its Embden-Meyerhof-Parnas pathway is defective. ... -
New insights into the biosynthesis of alginate in Pseudomonas fluorescens: from precursor synthesis to multiprotein factories
Maleki, Susan (Doctoral thesis at NTNU;2015:181, Doctoral thesis, 2015)Alginate is a biopolymer that has numerous industrial and medical applications due to its favorable material properties, which is greatly affected by the polymer chain length and monomer composition. Currently, all ...