Browsing NTNU Open by Author "Mahjoub, Ahlem Khachroub"

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    • Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation 

      Lentini, Germana; Famà, Agata; De Gaetano, Giuseppe Valerio; Coppolino, Francesco; Mahjoub, Ahlem Khachroub; Ryan, Liv; Lien, Egil; Espevik, Terje; Beninati, Concetta; Teti, Giuseppe (Peer reviewed; Journal article, 2023)
      During differentiation, neutrophils undergo a spontaneous pro-inflammatory program that is hypothesized here to be under caspase-8 control. In mice, intraperitoneal administration of the caspase-8 inhibitor z-IETD-fmk is ...