• Energy-efficiency of Cardiomyocyte Stimulation with Rectangular Pulses 

      Laasmaa, Martin; Lu, Pengfei; Veletic, Mladen; Louch, William Edward; Bergsland, Jacob; Balasingham, Ilangko; Vendelin, Marko (Journal article; Peer reviewed, 2019)
      In cardiac pacemaker design, energy expenditure is an important issue. This work aims to explore whether varying stimulation pulse configuration is a viable optimization strategy for reducing energy consumption by the ...
    • Molecular Communication Aspects of Potassium Intracellular Signaling in Cardiomyocytes 

      Lu, Pengfei; Veletic, Mladen; Bergsland, Jacob; Balasingham, Ilangko (Peer reviewed; Journal article, 2020)
      Cardiovascular diseases continue to be a leading cause of morbidity and mortality worldwide. Cardiomyocytes, as the elementary heart components, play a crucial role in maintaining a healthy heart by coordinating contractions ...
    • Multi-nodal nano-actuator pacemaker for energy-efficient stimulation of cardiomyocytes 

      Lu, Pengfei; Veletic, Mladen; Laasmaa, Martin; Vendelin, Marko; Louch, William Edward; Halvorsen, Per Steinar; Bergsland, Jacob; Balasingham, Ilangko (Journal article; Peer reviewed, 2019)
      There is continuous interest in maximizing the longevity of implantable pacemakers, which are effective in remedying and managing patients with arrhythmic heart disease. This paper accordingly first proposes miniature ...
    • Theoretical aspects of resting-state cardiomyocyte communication for multi-nodal nano-actuator pacemakers 

      Lu, Pengfei; Veletic, Mladen; Bergsland, Jacob; Balasingham, Ilangko (Peer reviewed; Journal article, 2020)
      The heart consists of billions of cardiac muscle cells—cardiomyocytes—that work in a coordinated fashion to supply oxygen and nutrients to the body. Inter-connected specialized cardiomyocytes form signaling channels through ...