Blar i NTNU Open på forfatter "Louch, William Edward"
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A computational pipeline for quantification of mouse myocardial stiffness parameters
Nordbø, Øyvind; Lamata, P.; Land, Sander; Niederer, Steven A.; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Martens, Harald; Gjuvsland, Arne Bjørke; Tøndel, Kristin; Torp, Hans; Lohezic, M; Schneider, Jürgen; Remme, Espen W.; Smith, Nicolas P; Omholt, Stig W; Vik, Jon Olav (Journal article; Peer reviewed, 2014)The mouse is an important model for theoretical–experimental cardiac research, and biophysically based whole organ models of the mouse heart are now within reach. However, the passive material properties of mouse myocardium ... -
Energy-efficiency of Cardiomyocyte Stimulation with Rectangular Pulses
Laasmaa, Martin; Lu, Pengfei; Veletic, Mladen; Louch, William Edward; Bergsland, Jacob; Balasingham, Ilangko; Vendelin, Marko (Journal article; Peer reviewed, 2019)In cardiac pacemaker design, energy expenditure is an important issue. This work aims to explore whether varying stimulation pulse configuration is a viable optimization strategy for reducing energy consumption by the ... -
Multi-nodal nano-actuator pacemaker for energy-efficient stimulation of cardiomyocytes
Lu, Pengfei; Veletic, Mladen; Laasmaa, Martin; Vendelin, Marko; Louch, William Edward; Halvorsen, Per Steinar; Bergsland, Jacob; Balasingham, Ilangko (Journal article; Peer reviewed, 2019)There is continuous interest in maximizing the longevity of implantable pacemakers, which are effective in remedying and managing patients with arrhythmic heart disease. This paper accordingly first proposes miniature ... -
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein; Øgaard, Jonas; Ohm, Ingrid Kristine; Slupphaug, Geir; Kusnierczyk, Anna; Fiane, Arnt E; Brorson, Sverre Henning; Zhang, Lili; Gullestad, Lars; Louch, William Edward; Iversen, Per Ole; Østlie, Ingunn; Klungland, Arne; Christensen, Geir Arve; Sjaastad, Ivar; Sætrom, Pål; Yndestad, Arne; Aukrust, Pål; Bjørås, Magnar; Finsen, Alexandra (Journal article; Peer reviewed, 2017)Myocardial infarction (MI) triggers a reparative response involving fibroblast proliferation and differentiation driving extracellular matrix modulation necessary to form a stabilizing scar. Recently, it was shown that a ...