• Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study. 

      Steyerberg, Ewout W; Wiegers, E; Sewalt, C.; Buki, Andras; Citerio, Giuseppe; De Keyser, Veronique; Ercole, Ari; Kunzmann, K.R.; Lanyon, Linda; Lecky, Fiona; Lingsma, Hester F; Manley, Geoffrey T; Nelson, D; Peul, Wilco; Stocchetti, Nino; von Steinbüchel, Nicole; Vande Vyvere, Thijs; Verheyden, Jan; Wilson, Lindsay; Maas, AIR; Menon, David; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røise, Olav; Skandsen, Toril; Røe, Cecilie (Peer reviewed; Journal article, 2019)
      BACKGROUND: The burden of traumatic brain injury (TBI) poses a large public health and societal problem, but the characteristics of patients and their care pathways in Europe are poorly understood. We aimed to characterise ...
    • Changing care pathways and between-center practice variations in intensive care for traumatic brain injury across Europe: a CENTER-TBI analysis 

      Huijbers, Jilske; Wiegers, E; Lingsma, Hester F; Citerio, Giuseppe; Maas, Andrew I.R.; Menon, David K; Ercole, Ari; Nelson, David; van der Jagt, Mathieu; Steyerberg, Ewout; Helbok, Raimund; Lecky, Fiona; Peul, Wilco; Birg, Tatiana; Zoerle, Tomaso; Carbonara, Marco; Stocchetti, Nino; Andelic, Nada; Andreassen, Lasse; Lund, Stine Borgen; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Sandrød, Oddrun; Schirmer-Mikalsen, Kari; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Brorsson, Camilla; Azzolini, Maria Luisa; Bartels, Ronald; Beer, Ronny; Bellander, Bo-Michael; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Beqiri, Erta; Blaabjerg, Morten; Buki, Andras; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emaliana; Calvi, Maria Rosa; Cameron, Peter; Guillermo, Carbayo Lozano; Sundström, Nina; Tibboel, Dick; Ples, Horia; Sakowitz, Oliver; Ziverte, Agate (Peer reviewed; Journal article, 2020)
      Purpose: To describe ICU stay, selected management aspects, and outcome of Intensive Care Unit (ICU) patients with traumatic brain injury (TBI) in Europe, and to quantify variation across centers. Methods: This is a ...
    • Comparison of Care System and Treatment Approaches for Patients with Traumatic Brain Injury in China versus Europe: A CENTER-TBI Survey Study 

      Feng, Junfeng; van Veen, Ernest; Chun, Yang; Huijben, Jilske A.; Lingsma, Hester F; Gao, Guoyi; jiang, jiyao; Maas, Andrew I. R.; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Traumatic brain injury (TBI) poses a huge public health and societal problem worldwide. Uncertainty exists on how care system and treatment approaches for TBI worked in China may differ from those in Europe. Better knowledge ...
    • Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury 

      Mikolic, Ana; van Klaveren, David; Oude Groeniger, Joost; Wiegers, E; Lingsma, Hester F; Zeldovich, Marina; von Steinbüchel, Nicole; Maas, Andrew I.R.; Roeters van Lennep, Jeanine; Polinder, Suzanne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina (Peer reviewed; Journal article, 2020)
      Traumatic brain injury (TBI) is a significant cause of disability, but little is known about sex and gender differences after TBI. We aimed to analyze the association between sex/gender, and the broad range of care pathways, ...
    • End-of-life practices in traumatic brain injury patients: Report of a questionnaire from the CENTER-TBI study 

      van Veen, Ernest; van der Jagt, Mathieu; Citerio, Guiseppe; Stocchetti, Nino; Epker, Jelle; Gommers, Diederik; Burdorf, Lex; Menon, David K; Maas, Andrew I.R.; Lingsma, Hester F; Kompanje, Erwin J.O.; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco (Peer reviewed; Journal article, 2020)
      Purpose We aimed to study variation regarding specific end-of-life (EoL) practices in the intensive care unit (ICU) in traumatic brain injury (TBI) patients. Materials and methods Respondents from 67 hospitals ...
    • Impact of Antithrombotic Agents on Radiological Lesion Progression in Acute Traumatic Brain Injury: A CENTER-TBI Propensity-Matched Cohort Analysis 

      Mathieu, Francois; Güting, Helge; Gravesteijn, Benjamin; Monteiro, Miguel; Glocker, Ben; Kornaropoulos, Evgenios; Kamnistas, Konstantinos; Robertson, Claudia; Levin, Harvey; Whitehouse, Daniel; Das, Tilak; Lingsma, Hester F; Maegele, Marc; Newcombe, Virginia F.J.; Menon, David K; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa (Peer reviewed; Journal article, 2020)
      An increasing number of elderly patients are being affected by traumatic brain injury (TBI) and a significant proportion are on pre-hospital antithrombotic therapy for cardio- or cerebrovascular indications. We have ...
    • Informed consent procedures in patients with an acute inability to provide informed consent: Policy and practice in the CENTER-TBI study 

      van Wijk, Roel P J; van Dijck, Jeroen T. J. M.; Timmers, Marjolein; van Veen, Ernest; Citerio, Giuseppe; Lingsma, Hester F; Maas, Andrew I. R.; Menon, David K; Peul, Wilco C.; Stocchetti, Nino; Kompanje, Erwin J.O.; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco (Peer reviewed; Journal article, 2020)
      Purpose: Enrolling traumatic brain injury (TBI) patients with an inability to provide informed consent in research is challenging. Alternatives to patient consent are not sufficiently embedded in European and national ...
    • Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury 

      Gravesteijn, BY; Nieboer, Daan; Ercole, Ari; Lingsma, Hester F; Nelson, David; Van Calster, Ben; Steyerberg, Ewout W; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Objective We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury. Study Design and Setting We performed logistic regression ...
    • Outcome Prediction after Moderate and Severe Traumatic Brain Injury: External Validation of Two Established Prognostic Models in 1742 European Patients 

      Dijkland, Simone; Retel Helmrich, Isabel; Nieboer, Daan; van der Jagt, Mathieu; Dippel, Diederik W.J.; Menon, David K; Stocchetti, Nino; Maas, Andrew I.R.; Lingsma, Hester F; Steyerberg, Ewout W; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Chevallard, Giorgio (Peer reviewed; Journal article, 2020)
      The International Mission on Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) and Corticoid Randomisation After Significant Head injury (CRASH) prognostic models predict functional outcome after ...
    • Prediction of Global Functional Outcome and Post-Concussive Symptoms after Mild Traumatic Brain Injury: External Validation of Prognostic Models in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study 

      Mikolic, Ana; Polinder, Suzanne; Steyerberg, Ewout W; Retel Helmrich, Isabel; Giacino, Joseph T.; Maas, Andrew I.R.; van der Naalt, Joukje; Voormolen, Daphne; von Steinbüchel, Nicole; Wilson, Lindsay; Lingsma, Hester F; van Klaveren, David; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco (Peer reviewed; Journal article, 2020)
      The majority of traumatic brain injuries (TBIs) are categorized as mild, according to a baseline Glasgow Coma Scale (GCS) score of 13–15. Prognostic models that were developed to predict functional outcome and persistent ...
    • Prehospital Management of Traumatic Brain Injury across Europe: A CENTER-TBI Study 

      Gravesteijn, BY; Sewalt, Charlie; Stocchetti, Nino; Citerio, Giuseppe; Ercole, Ari; Lingsma, Hester F; Von Steinbuchel, Nicole; Steyerberg, Ewout W; Wilson, Lindsay; Maas, Andrew I.R.; Menon, David K; Lecky, Fiona E.; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Cavallo, Simona; Chevallard, Giorgio; Chieregato, Arturo (Peer reviewed; Journal article, 2020)
      Background: Prehospital care for traumatic brain injury (TBI) is important to prevent secondary brain injury. We aim to compare prehospital care systems within Europe and investigate the association of system characteristics ...
    • Tracheostomy practice and timing in traumatic brain-injured patients: a CENTER-TBI study 

      Robba, Chiara; Galimberti, Stefania; Graziano, Francesca; Wiegers, E; Lingsma, Hester F; Iaquaniello, Carolina; Stocchetti, Nino; Menon, David; Citerio, Giuseppe; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Lund, Stine Borgen; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Sandrød, Oddrun; Schirmer-Mikalsen, Kari; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Beer, Ronny; Bellander, Bo-Michael; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Biqiri, Erta; Blaabjerg, Morten; Brorsson, Camilla; Buki, Andras; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Castaño-León, Ana M.; Chevallard, Giorgio; Chieregato, Arturo; Coburn, Mark; Coles, Jonathan; Cooper, Jamie; Correia, Marta; Czeiter, Endre (Peer reviewed; Journal article, 2020)
      Purpose Indications and optimal timing for tracheostomy in traumatic brain-injured (TBI) patients are uncertain. This study aims to describe the patients’ characteristics, timing, and factors related to the decision to ...
    • Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study. 

      Van Essen, Thomas; den Boogert, HF; Cnossen, MC; De Ruiter, Godard CW; Haitsma, Ian; Polinder, S; Steyerberg, Ewout W.; Menon, David; Maas, Andrew I. R.; Lingsma, Hester F; Peul, Wilco; Andelic, Nada; Helseth, Eirik; Roise, O; Røe, Cecilie; Vik, Anne; Skandsen, Toril; Anke, Audny; Frisvold, Shirin Kordasti; Andreassen, Lasse; Håberg, Asta (Journal article; Peer reviewed, 2018)
      Background Neurosurgical management of traumatic brain injury (TBI) is challenging, with only low-quality evidence. We aimed to explore differences in neurosurgical strategies for TBI across Europe. Methods A survey ...
    • Variation in the practice of tracheal intubation in Europe after traumatic brain injury: a prospective cohort study 

      Gravesteijn, BY; Sewalt, C.; Ercole, Ari; Lecky, Fiona; Menon, David; Steyerberg, Ewout W; Maas, AIR; Lingsma, Hester F; Klimek, Magdalena; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røise, Olav; Røe, Cecilie; Schirmer-Mikalsen, Kari; Sandrød, Oddrun; Borgen Lund, Stine (Peer reviewed; Journal article, 2020)
      Traumatic brain injury patients frequently undergo tracheal intubation. We aimed to assess current intubation practice in Europe and identify variation in practice. We analysed data from patients with traumatic brain injury ...