• Controlling for P-value inflation in allele frequency change in experimental evolution and artificial selection experiments 

      Kemppainen, Petri; Rønning, Bernt; Kvalnes, Thomas; Hagen, Ingerid Julie; Ringsby, Thor Harald; Billing, Anna Maria; Pärn, Henrik; Lien, Sigbjørn; Husby, Arild; Sæther, Bernt-Erik; Jensen, Henrik (Journal article; Peer reviewed, 2017)
      Experimental evolution studies can be used to explore genomic response to artificial and natural selection. In such studies, loci that display larger allele frequency change than expected by genetic drift alone are assumed ...
    • Functional Annotation of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture 

      Macqueen, Daniel J.; Primmer, Craig R.; Houston, Ross D.; Nowak, Barbara F.; Bernatchez, Louis; Bergseth, Steinar; Davidson, William S.; Gallardo-Escárate, Cristian; Goldammer, Tom; Guiguen, Yann; Iturra, Patricia; Kijas, James W.; Koop, Ben F.; Lien, Sigbjørn; Maass, Alejandro; Martin, Samuel A. M.; McGinnity, Philip; Montecino, Martin; Naish, Kerry; Nichols, Krista M.; Ólafsson, Kristinn; Omholt, Stig William; Palti, Yniv; Plastow, Graham S.; Rexroad, Caird E. 3rd; Rise, Matthew L.; Ritchie, Rachael J.; Sandve, Simen Rød; Schulte, Patricia M.; Tello, Alfredo; Vidal, Rodrigo; Vik, Jon Olav; Wargelius, Anna; Yáñez, José Manuel (Journal article; Peer reviewed, 2017)
      We describe an emerging initiative - the ‘Functional Annotation of All Salmonid Genomes’ (FAASG), which will leverage the extensive trait diversity that has evolved since a whole genome duplication event in the salmonid ...
    • Genome-wide association mapping for milk fat composition and fine mapping of a QTL for de novo synthesis of milk fatty acids on bovine chromosome 13 

      Olsen, Hanne Gro; Knutsen, Tim Martin; Kohler, Achim; Svendsen, Morten; Gidskehaug, Lars Halvor; Grove, Harald; Nome, Torfinn; Sodeland, Marte; Sundsaasen, Kristil Kindem; Kent, Matthew Peter; Martens, Harald; Lien, Sigbjørn (Journal article; Peer reviewed, 2017)
      Background Bovine milk is widely regarded as a nutritious food source for humans, although the effects of individual fatty acids on human health is a subject of debate. Based on the assumption that genomic selection offers ...
    • A genome-wide linkage map for the house sparrow (Passer domesticus) provides insights into the evolutionary history of the avian genome 

      Hagen, Ingerid Julie; Lien, Sigbjørn; Billing, Anna Maria; Elgvin, Tore Oldeide; Trier, Cassandra Nicole; Niskanen, Alina K.; Tarka, Maja; Slate, Jon; Sætre, Glenn-Peter; Jensen, Henrik (Peer reviewed; Journal article, 2020)
      The house sparrow is an important model species for studying physiological, ecological and evolutionary processes in wild populations. Here, we present a medium density, genome wide linkage map for house sparrow (Passer ...
    • Inferences of genetic architecture of bill morphology in house sparrow using a high-density SNP array point to a polygenic basis 

      Lundregan, Sarah; Hagen, Ingerid Julie; Gohli, Jostein; Niskanen, Alina Katariina; Kemppainen, Petri; Ringsby, Thor Harald; Kvalnes, Thomas; Pärn, Henrik; Rønning, Bernt; Holand, Håkon; Ranke, Peter Sjolte; Båtnes, Anna Solvang; Selvik, Linn-Karina M.; Lien, Sigbjørn; Sæther, Bernt-Erik; Husby, Arild; Jensen, Henrik (Journal article; Peer reviewed, 2018)
      Understanding the genetic architecture of quantitative traits can provide insights into the mechanisms driving phenotypic evolution. Bill morphology is an ecologically important and phenotypically variable trait, which is ...
    • Life-stage associated remodeling of lipid metabolism regulation in Atlantic salmon 

      Gillard, Gareth Benjamin; Harvey, Thomas Nelson; Gjuvsland, Arne Bjørke; Jin, Yang; Thomassen, Magny Sissel S.; Lien, Sigbjørn; Leaver, Michael; Torgersen, Jacob Seilø; Hvidsten, Torgeir Rhoden; Vik, Jon Olav; Sandve, Simen Rød (Journal article; Peer reviewed, 2018)
      Atlantic salmon migrates from rivers to sea to feed, grow and develop gonads before returning to spawn in freshwater. The transition to marine habitats is associated with dramatic changes in the environment, including water ...
    • Modular chromosome rearrangements reveal parallel and nonparallel adaptation in a marine fish 

      Kess, Tony; Bentzen, Paul; Lehnert, Sarah; Sylvester, Emma V. A.; Lien, Sigbjørn; Kent, Matthew Peter; Sinclair-Waters, Marion; Morris, Corey; Wringe, Brendan; Fairweather, Robert; Bradbury, Ian R. (Journal article; Peer reviewed, 2019)
      Genomic architecture and standing variation can play a key role in ecological adaptation and contribute to the predictability of evolution. In Atlantic cod (Gadus morhua), four large chromosomal rearrangements have been ...
    • Signs of adaptation to trace metal contamination in a common urban bird 

      Andrew, Samuel C.; Taylor, Mark Patrick; Lundregan, Sarah; Lien, Sigbjørn; Jensen, Henrik; Griffith, Simon C. (Journal article; Peer reviewed, 2018)
      Metals and metalloids at elevated concentrations can be toxic to both humans and wildlife. In particular, lead exposure can act as a stressor to wildlife and cause negative effects on fitness. Any ability to adapt to stress ...
    • The Atlantic salmon genome provides insights into rediploidization 

      Lien, Sigbjørn; Koop, Ben F; Sandve, Simen Rød; Miller, Jason R.; Kent, Matthew Peter; Nome, Torfinn; Hvidsten, Torgeir Rhoden; Leong, Jong; Minkley, David R.; Zimin, Aleksey; Grammes, Fabian; Grove, Harald; Gjuvsland, Arne Bjørke; Walenz, Brian; Hermansen, Russell A.; von Schalburg, Kristian R.; Rondeau, Eric; Genova, Alex Di; Antony Samy, Jeevan Karloss; Vik, Jon Olav; Vigeland, Magnus Dehli; Caler, Lis; Grimholt, Unni; Jentoft, Sissel; Våge, Dag Inge; de Jong, Pieter J.; Moen, Thomas; Baranski, Matthew; Palti, Yniv; Smith, Douglas W.; Yorke, James A.; Nederbragt, Alexander J.; Tooming-Klunderud, Ave; Jakobsen, Kjetill Sigurd; Jiang, Xuanting; Fan, Dingding; Hu, Yan; Liberles, David A.; Vidal, Rodrigo; Iturra, Patricia; Jones, Steven J.M.; Jonassen, Inge; Maass, Alejandro; Omholt, Stig William; Davidson, William S (Journal article; Peer reviewed, 2016)
      The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique opportunities to learn about the evolutionary fate ...
    • The genomic mosaicism of hybrid speciation 

      Elgvin, Tore Oldeide; Trier, Cassandra Nicole; Tørresen, Ole Kristian; Hagen, Ingerid; Lien, Sigbjørn; Nederbragt, Alexander Johan; Ravinet, Mark Simon Paul; Jensen, Henrik; Sætre, Glenn-Peter (Journal article; Peer reviewed, 2017)
      Hybridization is widespread in nature and, in some instances, can result in the formation of a new hybrid species. We investigate the genetic foundation of this poorly understood process through whole-genome analysis of ...