Browsing NTNU Open by Author "Lie, Benedicte Alexandra"
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The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial
Gjefsen, Elisabeth; Bråten, Lars Christian Haugli; Goll, Guro Løvik; Wigemyr, Monica; Bolstad, Nils; Valberg, Morten; Schistad, Ellina Iordanova; Marchand, Gunn Hege; Granviken, Fredrik; Selmer, Kaja Kristine; Johanessen, Anne Froholdt; Haugen, Anne Julsrud; Dagestad, Magnhild Hammersland; Vetti, Nils; Bakland, Gunnstein; Lie, Benedicte Alexandra; Haavardsholm, Espen A.; Nilsen, Aksel Thuv; Holmgard, Thor Einar; Kadar, Thomas; Kvien, Tore Kristian; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Espeland, Ansgar; Storheim, Kjersti; Zwart, John-Anker (Peer reviewed; Journal article, 2020)Low back pain is common and a significant number of patients experience chronic low back pain. Current treatment options offer small to moderate effects. Patients with vertebral bone marrow lesions visualized as Modic ... -
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
Bråten, Lars Christian Haugli; Rolfsen, Mads Peder; Espeland, Ansgar; Wigemyr, Monica; Assmus, Jörg; Froholdt, Anne; Haugen, Anne Julsrud; Marchand, Gunn Hege; Kristoffersen, Per M; Lutro, Olav; Randen, Sigrun; Wilhelmsen, Maja; Winsvold, Bendik K S; Kadar, Thomas; Holmgard, Thor Einar; Vigeland, Maria Dehli; Vetti, Nils; Nygaard, Øystein Petter; Lie, Benedicte Alexandra; Hellum, Christian; Anke, Audny; Grotle, Margreth; Schistad, Ellina Iordanova; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (Journal article; Peer reviewed, 2019)Objective To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes). Design Double ... -
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Saevarsdottir, Saedis; Stefansdottir, Lilja; Sulem, Patrick; Thorleifsson, Gudmar; Ferkingstad, Egil; Rutsdottir, Gudrun; Glintborg, Bente; Westerlind, Helga; Grondal, Gerdur; Loft, Isabella C; Sorensen, Signe Bek; Lie, Benedicte Alexandra; Brink, Mikael; Arlestig, Lisbeth; Arnthorsson, Asgeir Orn; Baecklund, Eva; Banasik, Karina; Bank, Steffen; Bjorkman, Lena I; Ellingsen, Torkell; Erikstrup, Christian; Frei, Oleksandr; Gjertsson, Inger; Gudbjartsson, Daniel F; Gudjonsson, Sigurjon A; Halldorsson, Gisli H; Hendricks, Oliver; Hillert, Jan; Hogdall, Estrid; Jacobsen, Søren; Jensen, Dorte Vendelbo; Jonsson, Helgi Freyr; Kastbom, Alf; Kockum, Ingrid; Kristensen, Salome; Kristjansdottir, Helga; Larsen, Margit H; Linauskas, Asta; Hauge, Ellen-Margrethe; Loft, Anne G; Ludviksson, Bjorn R; Lund, Sigrun H; Markusson, Thorsteinn; Masson, Gisli; Melsted, Pall; Moore, Kristjan H S; Munk, Heidi; Nielsen, Kaspar R; Norddahl, Gudmundur L; Oddsson, Asmundur; Olafsdottir, Thorunn A; Olason, Pall I; Olsson, Tomas; Ostrowski, Sisse Rye; Hørslev-Petersen, Kim; Rognvaldsson, Solvi; Sanner, Helga; Silberberg, Gilad N; Stefansson, Hreinn; Sørensen, Erik; Sørensen, Inge J; Turesson, Carl; Bergman, Thomas; Alfredsson, Lars; Kvien, Tore Kristian; Brunak, Søren; Steinsson, Kristján; Andersen, Vibeke; Andreassen, Ole; Rantapää-Dahlqvist, Solbritt; Hetland, Merete Lund; Klareskog, Lars; Askling, Johan; Padyukov, Leonid; Pedersen, Ole Bv; Thorsteinsdottir, Unnur; Jonsdottir, Ingileif; Stefansson, Kari (Peer reviewed; Journal article, 2022)Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% ... -
Polymorphisms in the TP53-MDM2-MDM4-axis in patients with rheumatoid arthritis
Gansmo, Liv Beathe; Lie, Benedicte Alexandra; Mæhlen, Marthe Thoresen; Vatten, Lars Johan; Romundstad, Pål Richard; Hveem, Kristian; Lønning, Per Eystein; Knappskog, Stian (Peer reviewed; Journal article, 2021)Background In addition to being a tumour suppressor, TP53 is a suppressor of inflammation, and dysfunction of this gene has been related to autoimmune diseases. Patients with autoimmunity, such as rheumatoid arthritis ... -
T-cell characterization of coagulation factor V and methotrexate treatment
Ringen Jøråsen, Ingvild (Master thesis, 2021)