Browsing NTNU Open by Author "Li, Youxian"
Now showing items 1-4 of 4
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Cell-Type-Specific Transcription of Innate Immune Regulators in response to HMPV Infection
Loevenich, Simon; Malmo, Jostein; Liberg, Ann Magritt; Sherstova, Tatyana; Li, Youxian; Rian, Kristin; Johnsen, Ingvild Bjellmo; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2019)Human metapneumovirus (HMPV) may cause severe respiratory disease. The early innate immune response to viruses like HMPV is characterized by induction of antiviral interferons (IFNs) and proinflammatory immune mediators ... -
Characterization of signaling pathways regulating the expression of pro-inflammatory long form thymic stromal lymphopoietin upon human metapneumovirus infection
Li, Youxian; Lund, Cecilie; Nervik, Ida; Loevenich, Simon; Døllner, Henrik; Anthonsen, Marit Walbye; Johnsen, Ingvild Bjellmo (Journal article; Peer reviewed, 2018)Thymic stromal lymphopoietin (TSLP) is associated with several allergic diseases including asthma. Two isoforms of TSLP exist in humans, a long form (lfTSLP) and a short form (sfTSLP), displaying distinct immunological ... -
Human Metapneumovirus Infection Inhibits Cathelicidin Antimicrobial Peptide Expression in Human Macrophages
Li, Youxian; Østerhus, Stine; Johnsen, Ingvild Bjellmo (Journal article; Peer reviewed, 2018)Human cathelicidin antimicriobial peptide (CAMP) is a critical component of host innate immunity with both antimicrobial and immunomodulatory functions. Several pathogens have been shown to downregulate CAMP expression, ... -
Novel insights into the innate immune responses to human metapneumovirus infection or changes in osmolality
Li, Youxian (Doctoral theses at NTNU;2018:323, Doctoral thesis, 2018)Ny innsikt i de medfødte immunresponsene mot humant metapneumovirus infeksjon eller endringer i osmolalitet Sammendraget: Kroppens medfødte immunsystem gir umiddelbar beskyttelse mot infeksjoner og styrer de påfølgende ...