• Effect of Acoustic Radiation Force on the Distribution of Nanoparticles in Solid Tumors. 

      Afadzi, Mercy; Myhre, Ola Finneng; Yemane, Petros Tesfamichael; Bjørkøy, Astrid; Torp, Sverre Helge; van Wamel, Annemieke; Lelu, Sylvie; Angelsen, Bjørn Atle Johan; Davies, Catharina de Lange (Peer reviewed; Journal article, 2020)
      Acoustic radiation force (ARF) might improve the distribution of nanoparticles (NPs) in tumors. To study this, tumors growing subcutaneously in mice were exposed to focused ultrasound (FUS) either 15 min or 4 h after the ...
    • Labeling nanoparticles: Dye leakage and altered cellular uptake 

      Snipstad, Sofie; Hak, Sjoerd; Baghirov, Habib; Sulheim, Einar; Mørch, Ýrr Asbjørg; Lelu, Sylvie; von Haartman, Eva; Bäck, Marcus; Nilsson, Peter R; Klymchenko, Andrey S; Davies, Ruth Catharina de Lange; Åslund, Andreas (Journal article, 2016)
      In vitro and in vivo behavior of nanoparticles (NPs) is often studied by tracing the NPs with fluorescent dyes. This requires stable incorporation of dyes within the NPs, as dye leakage may give a wrong interpretation of ...
    • Primary Porcine Brain Endothelial Cells as In Vitro Model to Study Effects of Ultrasound and Microbubbles on Blood-Brain Barrier Function 

      Lelu, Sylvie; Afadzi, Mercy; Berg, Sigrid; Åslund, Andreas; Torp, Sverre Helge; Sattler, Wolfgang; Davies, Ruth Catharina de Lange (Journal article; Peer reviewed, 2017)
      Focused ultrasound in the presence of microbubbles transiently and reversibly opens the blood-brain barrier (BBB) in rodents and humans thereby providing a time window for increased drug delivery into brain tissue. To get ...
    • Quantification and Qualitative Effects of Different PEGylations on Poly(butyl cyanoacrylate) Nanoparticles 

      Åslund, Andreas; Sulheim, Einar; Snipstad, Sofie; von Haartman, Eva; Baghirov, Habib; Starr, Nichola; Løvmo, Mia Kvåle; Lelu, Sylvie; Scurr, David; Davies, Catharina De Lange; Schmid, Ruth; Mørch, Yrr Asbjørg (Journal article, 2017)
      Protein adsorption on nanoparticles (NPs) used in nanomedicine leads to opsonization and activation of the complement system in blood, which substantially reduces the blood circulation time of NPs. The most commonly used ...
    • Status Report of the Trondheim Radiocarbon Laboratory 

      Seiler, Martin; Grootes, Pieter Meiert; Haarsaker, John Øystein; Lelu, Sylvie; Rzadeczka-Juga, Izabela; Stene, Sølvi; Svarva, Helene Løvstrand; Thun, Terje; Værnes, Einar; Nadeau, Marie-Josée (Journal article; Peer reviewed, 2019)
      The Trondheim radiocarbon (14C) laboratory has evolved from a traditional radiocarbon decay counting laboratory to an accelerator mass spectrometry (AMS) facility primarily measuring 14C. This evolution required adjustments ...