• A multimodal image guiding system for Navigated Ultrasound Bronchoscopy (EBUS): A human feasibility study 

      Sorger, Hanne; Hofstad, Erlend Fagertun; Amundsen, Tore; Langø, Thomas; Bakeng, Janne Beate Lervik; Leira, Håkon Olav (Journal article; Peer reviewed, 2017)
      Background Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is the endoscopic method of choice for confirming lung cancer metastasis to mediastinal lymph nodes. Precision is crucial for correct staging ...
    • A new procedure for automatic path planning in bronchoscopy 

      Ciobirca, C; Langø, Thomas; Gruionu, G; Leira, Håkon Olav; Gruionu, Lucian; Pastrama, SD (Journal article; Peer reviewed, 2018)
      Virtual bronchoscopy is often used for planning a real bronchoscopy procedure. Software applications are developed for virtual bronchoscopy, involving usually segmentation of the tracheobronchial tree from the medical image ...
    • Accuracy of electromagnetic tracking with a prototype field generator in an interventional OR setting 

      Bø, Lars Eirik; Leira, Håkon Olav; Tangen, Geir Arne; Hofstad, Erlend Fagertun; Amundsen, Tore; Langø, Thomas (Journal article; Peer reviewed, 2012)
      Purpose: The authors have studied the accuracy and robustness of a prototype electromagnetic window field generator (WFG) in an interventional radiology suite with a robotic C-arm. The overall purpose is the development ...
    • Airway segmentation and centerline extraction from thoracic CT - Comparison of a new method to state of the art commercialized methods 

      Reynisson, Pall Jens; Scali, Marta; Smistad, Erik; Hofstad, Erlend Fagertun; Leira, Håkon Olav; Lindseth, Frank; Hernes, Toril A. Nagelhus; Amundsen, Tore; Sorger, Hanne; Langø, Thomas (Peer reviewed; Journal article, 2015)
      Introduction Our motivation is increased bronchoscopic diagnostic yield and optimized preparation, for navigated bronchoscopy. In navigated bronchoscopy, virtual 3D airway visualization is often used to guide a bronchoscopic ...
    • Behandling av lungekreft med immunterapi ved St. Olavs Hospital 2019-2020 

      Lien, Mari Øren (Master thesis, 2023)
      Vi undersøkte bruken av immunterapi for behandling av lungekreft ved lungeavdeling St. Olavs hospital i perioden 2019-2020. Vi fant 85 pasienter, 45 menn og 40 kvinner. Median alder ved debut var 69 år. 61 personer hadde ...
    • Bronchoscopy using a head-mounted mixed reality device—a phantom study and a first in-patient user experience 

      Kildahl-Andersen, Arne; Hofstad, Erlend Fagertun; Sorger, Hanne; Amundsen, Tore; Langø, Thomas; Leira, Håkon Olav; Kiss, Gabriel Hanssen (Peer reviewed; Journal article, 2023)
      Background: Bronchoscopy for peripheral lung lesions may involve image sources such as computed tomography (CT), fluoroscopy, radial endobronchial ultrasound (R-EBUS), and virtual/electromagnetic navigation bronchoscopy. ...
    • Development of an image guidance research system for bronchoscopy 

      Leira, Håkon Olav (Doktoravhandlinger ved NTNU, 1503-8181; 2012:260, Doctoral thesis, 2012)
      This project has been carried out as collaboration between the Department of Thoracic Medicine at St. Olavs Hospital and the Department of Medical Technology at SINTEF, both in Trondheim, Norway. The team at SINTEF has ...
    • Development of navigated ultrasound bronchoscopy 

      Sorger, Hanne (Doctoral theses at NTNU;2018:78, Doctoral thesis, 2018)
      Lung cancer staging of mediastinal lymph nodes with convex probe endobronchial ultrasound transbronchial needle aspiration (CP-EBUS-TBNA) is a challenge to the bronchoscopist. Small, multiple targets are involved, and the ...
    • Dynamisk modell av pH, O2- og CO2-metning i blod 

      Eldhuset, Astrid (Master thesis, 2016)
      Oksygenterapi for personer med respirasjonslidelser gjennomføres idag ved manuell justering av tilført oksygenmengde. Denne reguleringsformen er lite optimal da både feiltolkning av medisinske indikatorer (hovedsakelig ...
    • Evaluering av PET-CT ved lungekreftutredning - Sammenligning før og etter innføring av PET-CT ved St. Olavs Hospital 

      Bruteig, Johannes Gihle; Ullern, Andreas (Master thesis, 2016)
      Bakgrunn: PET-CT er et viktig verktøy i stadieinndelingen av lungekreft. Inntil høsten 2013 ble alle pasienter fra Midt-Norge sendt til Bergen (Haukeland sykehus) eller Oslo (OUS eller Aleris) for denne undersøkelsen. Etter ...
    • Improved Bronchoscopy by new image guided Approach 

      Reynisson, Páll Jens (Doctoral theses at NTNU;2018:81, Doctoral thesis, 2018)
      Navigation in bronchoscopy has developed into a feasible approach for lung diagnostics since introduced in 1998. The concept combines computer generated models from patient CT data with position and orientation tracking ...
    • Intraoperative localized constrained registration in navigated bronchoscopy 

      Hofstad, Erlend Fagertun; Sorger, Hanne; Bakeng, Janne Beate Lervik; Gruionu, Lucian; Leira, Håkon Olav; Amundsen, Tore; Langø, Thomas (Journal article; Peer reviewed, 2017)
      Purpose One of the major challenges in electromagnetic navigated bronchoscopy is the navigation accuracy. An initial rigid image-to-patient registration may not be optimal for the entire lung volume, as the lung tissue ...
    • Lungekreftutredning ved Sykehuset Levanger og St. Olavs Hospital i perioden 2008-2018 – Kvalitet og utviklingstrender. 

      Klonteig, Kristoffer Bolt-Hansen (Master thesis, 2020)
      Bakgrunn Tidlig, rask og presis vevsdiagnose, samt korrekt utvelgelse av pasienter til kurativ behandling tilstrebes for bedre pasientoverlevelse ved lungekreft. Tradisjonelt sett har bronkoskopi vært den foretrukne ...
    • Mediastinal lymph nodes segmentation using 3D convolutional neural network ensembles and anatomical priors guiding 

      Bouget, David Nicolas Jean-Mar; Pedersen, André; Vanel, Johanna; Leira, Håkon Olav; Langø, Thomas (Peer reviewed; Journal article, 2022)
      As lung cancer evolves, the presence of potentially malignant lymph nodes must be assessed to properly estimate disease progression and select the best treatment strategy. A method for accurate and automatic segmentation ...
    • A new removable airway stent 

      Amundsen, Tore; Sørhaug, Sveinung; Leira, Håkon Olav; Tyvold, Stig Sverre; Langø, Thomas; Hammer, Tommy Arild; Manstad-Hulaas, Frode; Mattsson, Erney (Peer reviewed; Journal article, 2016)
      Background Malignant airway obstruction is a feared complication and will most probably occur more frequently in the future because of increasing cancer incidence and increased life expectancy in cancer patients. Minimal ...
    • A novel clip-on device for electromagnetic tracking in endobronchial ultrasound bronchoscopy 

      Kildahl-Andersen, Arne; Hofstad, Erlend Fagertun; Peters, Karlijn; Van Beek, Gregory; Sorger, Hanne; Amundsen, Tore; Langø, Thomas; Leira, Håkon Olav (Peer reviewed; Journal article, 2022)
      Introduction The established method for assessment of mediastinal and hilar lymph nodes is endobronchial ultrasound bronchoscopy (EBUS) with needle aspirations. Previously, we presented an electromagnetic navigation ...
    • Peripheral tumour targeting using open-source virtual bronchoscopy with electromagnetic tracking: a multi-user pre-clinical study 

      Jaeger, Herman Alexander; Trauzettel, Fabian; Nardelli, Pietro; Daverieux, Federico; Hofstad, Erlend Fagertun; Leira, Håkon Olav; Kennedy, Marcus P; Langø, Thomas; Cantillon-Murphy, Pádraig (Journal article; Peer reviewed, 2018)
      Objectives: The goal was to demonstrate the utility of open-source tracking and visualisation tools in the targeting of lung cancer. Material and methods: The study demonstrates the first deployment of the Anser electromagnetic ...
    • Pulmonologist evaluation on new CT visualization for guidance to lung lesions during bronchoscopy 

      Reynisson, Pall Jens; Leira, Håkon Olav; Langø, Thomas; Tangen, Geir Arne; Hatlen, Peter; Amundsen, Tore; Hofstad, Erlend Fagertun (Journal article; Peer reviewed, 2018)
      Objective: Endoluminal visualization in virtual and video bronchoscopy lacks information about the surrounding structures, and the traditional 2 D axial, coronal and sagittal CT views can be difficult to interpret. To ...
    • Using the CustusX toolkit to create an image guided bronchoscopy application: Fraxinus 

      Bakeng, Janne Beate Lervik; Hofstad, Erlend Fagertun; Solberg, Ole Vegard; Eiesland, Jon Wostryck; Tangen, Geir Arne; Amundsen, Tore; Langø, Thomas; Reinertsen, Ingerid; Selbekk, Tormod; Leira, Håkon Olav (Journal article; Peer reviewed, 2019)
      Purpose The aim of this paper is to show how a specialized planning and guidance application called Fraxinus, can be built on top of the CustusX platform (www.custusx.org), which is an open source image-guided intervention ...
    • Utvikling og evaluering av en simulator for bronkoskopi-opplæring bygd på åpent tilgjengelige komponenter 

      Ellingsrud, Emmy Bayer; Storeheier, Marta Emilie Marklin (Master thesis, 2023)
      Utvikling og evaluering av en simulator for bronkoskopi-opplæring bygd på åpent tilgjengelige komponenter Introduksjon Bronkoskopi er lungelegers viktigste invasive verktøy for diagnostikk av infeksjoner, lungekreft og ...