Browsing NTNU Open by Author "Leach, Martin O"
Now showing items 1-3 of 3
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Characterisation of fibrosis in chemically-induced rat mammary carcinomas using multi-modal endogenous contrast MRI on a 1.5T clinical platform
Jerome, Neil Peter; Boult, Jessica; Orton, Matthew R; d'Arcy, James; Nerurkar, Ashutosh; Leach, Martin O; Koh, Dow-Mu; Collins, David J.; Robinson, Simon (Journal article; Peer reviewed, 2018)Objectives To determine the ability of multi-parametric, endogenous contrast MRI to detect and quantify fibrosis in a chemically-induced rat model of mammary carcinoma. Methods Female Sprague-Dawley rats (n=18) were ... -
Non-Invasive Prostate Cancer Characterization with Diffusion-Weighted MRI: Insight from In silico Studies of a Transgenic Mouse Model
Hill, Deborah Katherine; Heindl, Andreas; Zormpas-Petridis, Konstantinos; Collins, David J.; Euceda, Leslie R.; Rodrigues, Daniel; Moestue, Siver Andreas; Jamin, Yann; Koh, Dow-Mu; Yuan, Yinyin; Bathen, Tone Frost; Leach, Martin O; Blackledge, Matthew D. (Journal article; Peer reviewed, 2017)Diffusion-weighted magnetic resonance imaging (DWI) enables non-invasive, quantitative staging of prostate cancer via measurement of the apparent diffusion coefficient (ADC) of water within tissues. In cancer, more advanced ... -
Post-radiotherapy apparent diffusion coefficient (ADC) in children and young adults with high-grade gliomas and diffuse intrinsic pontine gliomas
Carceller, Fernando; Jerome, Neil Peter; Fowkes, Lucy; Khabra, Komel; Mackinnon, Andrew; Bautista, Fransisco; Marshall, Lynley; Vaidya, Sucheta; Mandeville, Henry; Morgan, Veronica; Leach, Martin O; Koh, Dow-Mu (Journal article; Peer reviewed, 2019)Objectives: Diffusion-weighted magnetic resonance imaging (DW-MRI) offers potential to monitor response and predict survival in high-grade gliomas (HGG) and diffuse intrinsic pontine gliomas (DIPG). We hypothesized that ...