• Genome-Wide Association Study to Identify Common Variants Associated with Brachial Circumference: A Meta-Analysis of 14 Cohorts 

      Boraska, V; Day-Williams, A; Franklin, CS; Elliott, KS; Panoutsopoulou, K; Tachmazidou, I; Albrecht, E; Bandinelli, S; Beilin, L; Bochud, M; Cadby, G; Ernst, F; Evans, David M.; Hayward, C; Hicks, AA; Huffman, Jennifer; Huth, C; James, AL; Klopp, N; Kolcic, I; Kutalik, Z; Lawlor, Debbie A.; Musk, AW; Pehlic, M; Pennell, CE; Perry, JRB; Peters, Annette; Polasek, O; St Pourcain, B; Ring, SM; Salvi, E; Schipf, S; Staessen, JA; Teumer, A; Timpson, N; Vitart, V; Warrington, NM; Yaghootkar, H; Zemunik, T; Zgaga, L; An, P; Anttila, V; Borecki, IB; Holmen, Jostein; Ntalla, I; Palotie, A; Pietilainen, KH; Wedenoja, J; Winsvold, Bendik Kristoffer Slagsvold; Dedoussis, GV; Kaprio, J; Province, MA; Zwart, John-Anker; Burnier, M; Campbell, H; Cusi, D; Smith, GD; Frayling, TM; Gieger, C; Palmer, LJ; Pramstaller, PP; Rudan, I; Volzke, H; Wichmann, HE; Wright, AF; Zeggini, E (Journal article; Peer reviewed, 2012)
      Brachial circumference (BC), also known as upper arm or mid arm circumference, can be used as an indicator of muscle mass and fat tissue, which are distributed differently in men and women. Analysis of anthropometric ...
    • Investigating causal relations between sleep traits and risk of breast cancer in women: Mendelian randomisation study 

      Richmond, Rebecca C.; Anderson, Emma L.; Dashti, Hassan S.; Jones, Samuel E.; Lane, Jacqueline M.; Strand, Linn B; Brumpton, Ben Michael; Rutter, Martin K.; Wood, Andrew R.; Straif, Kurt; Relton, Caroline L.; Munafò, Marcus; Frayling, Timothy M.; Martin, Richard M.; Saxena, Richa; Weedon, Michael N.; Lawlor, Debbie A.; Smith, George Davey (Peer reviewed; Journal article, 2019)
      Objective To examine whether sleep traits have a causal effect on risk of breast cancer. Design Mendelian randomisation study. Setting UK Biobank prospective cohort study and Breast Cancer Association Consortium ...
    • Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight 

      Moen, Gunn-Helen; Beaumont, Robin N.; Grarup, Niels; Sommer, Christine; Shields, Beverley M.; Lawlor, Debbie A.; Freathy, Rachel M.; Evans, David M.; Warrington, Nicole Maree (Peer reviewed; Journal article, 2021)
      Background Lower maternal serum vitamin B12 (B12) and folate levels have been associated with lower offspring birthweight, in observational studies. The aim of this study was to investigate whether this relationship is ...
    • Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium 

      Ronkainen, Justiina; Heiskala, Anni; Vehmeijer, Florianne O.; Lowry, Estelle; Caramaschi, Doretta; Estrada Gutierrez, Guadalupe; Heiss, Jonathan A.; Hummel, Nadine; Keikkala, Elina; Kvist, Tuomas; Kupsco, Allison; Melton, Phillip E.; Pesce, Giancarlo; Soomro, Munawar Hussain; Vives-Usano, Marta; Baïz, Nour; Binder, Elisabeth B.; Czamara, Darina; Guxens, Mònica; Mustaniemi, Sanna; London, Stephanie J.; Rauschert, Sebastian; Vääräsmäki, Marja; Vrijheid, Martine; Ziegler, Anette-G.; Annesi-Maesano, Isabella; Bustamante, Mariona; Huang, Rae-Chi; Hummel, Sandra; Just, Allan C.; Kajantie, Eero Olavi; Lahti, Jari; Lawlor, Debbie A.; Räikkönen, Katri; Jarvelin, Marjo-Riitta; Felix, Janine F.; Sebert, Sylvain (Peer reviewed; Journal article, 2021)
      Altered maternal haemoglobin levels during pregnancy are associated with pre-clinical and clinical conditions affecting the fetus. Evidence from animal models suggests that these associations may be partially explained by ...
    • Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort 

      Moen, Gunn-Helen; Brumpton, Ben Michael; Willer, Cristen J.; Åsvold, Bjørn Olav; Birkeland, Kåre I.; Wang, Geng; Neale, Michael C.; Freathy, Rachel M.; Smith, George Davey; Lawlor, Debbie A.; Kirkpatrick, Robert M.; Warrington, Nicole Maree; Evans, David M. (Peer reviewed; Journal article, 2020)
      There is a robust observational relationship between lower birthweight and higher risk of cardiometabolic disease in later life. The Developmental Origins of Health and Disease (DOHaD) hypothesis posits that adverse ...