• Absolute Risk of Oropharyngeal Cancer After an HPV16-E6 Serology Test and Potential Implications for Screening: Results From the Human Papillomavirus Cancer Cohort Consortium 

      Robbins, Hilary A.; Ferreiro-Iglesias, Aida; Waterboer, Tim; Brenner, Nicole; Nygård, Mari; Bender, Noemi; Schroeder, Lea; Hildesheim, Allan; Pawlita, Michael; D'Souza, Gypsyamber; Visvanathan, Kala; Langseth, Hilde; Schlecht, Nicolas F.; Tinker, Lesley F.; Agalliu, Ilir; Wassertheil-Smoller, Sylvia; Ness-Jensen, Eivind; Hveem, Kristian; Grioni, Sara; Kaaks, Rudolf; Sánchez, Maria-Jose; Weiderpass, Elisabete; Giles, Graham G.; Milne, Roger L.; Cai, Qiuyin; Blot, William J.; Zheng, Wei; Weinstein, Stephanie J.; Albanes, Demetrius; Huang, Wen-Yi; Freedman, Neal D.; Kreimer, Aimée R; Johansson, Mattias; Brennan, Paul (Peer reviewed; Journal article, 2022)
      PURPOSE Seropositivity for the HPV16-E6 oncoprotein is a promising marker for early detection of oropharyngeal cancer (OPC), but the absolute risk of OPC after a positive or negative test is unknown. METHODS We ...
    • Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia 

      Watts, Eleanor L.; Perez-Cornago, Aurora; Fensom, Georgina K.; Smith-Byrne, Karl; Noor, Urwah; Andrews, Colm D.; Gunter, Marc J.; Holmes, Michael V.; Martin, Richard M.; Tsilidis, Konstantinos K.; Albanes, Demetrius; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Chen, Chu; Cohn, Barbara A.; Dimou, Niki L.; Ferrucci, Luigi; Flicker, Leon; Freedman, Neal D.; Giles, Graham G.; Giovannucci, Edward L.; Goodman, Gary E.; Haiman, Christopher A.; Hankey, Graeme J.; Huang, Jiaqi; Huang, Wen-Yi; Hurwitz, Lauren M.; Kaaks, Rudolf; Knekt, Paul; Kubo, Tatsuhiko; Langseth, Hilde; Laughlin, Gail; Le Marchand, Loic; Luostarinen, Tapio; MacInnis, Robert J.; Mäenpää, Hanna O.; Männistö, Satu; Metter, E. Jeffrey; Mikami, Kazuya; Mucci, Lorelei A.; Olsen, Anja; Ozasa, Kotaro; Palli, Domenico; Penney, Kathryn L.; Platz, Elizabeth A.; Rissanen, Harri; Sawada, Norie; Schenk, Jeannette M.; Stattin, Pär; Tamakoshi, Akiko; Thysell, Elin; Tsai, Chiaojung Jillian; Tsugane, Shoichiro; Vatten, Lars Johan; Weiderpass, Elisabete; Weinstein, Stephanie J.; Wilkens, Lynne R.; Yeap, Bu B.; Allen, Naomi E.; Key, Timothy J.; Travis, Ruth C. (Peer reviewed; Journal article, 2022)
      Previous studies had limited power to assess the associations of testosterone with aggressive disease as a primary endpoint. Further, the association of genetically predicted testosterone with aggressive disease is not ...
    • Circulating Sex Hormone Levels and Risk of Esophageal Adenocarcinoma in a Prospective Study in Men 

      Xie, Shao-Hua; Ness-Jensen, Eivind; Rabbani, Sirus; Langseth, Hilde; Gislefoss, Randi Elin; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2019)
      OBJECTIVES: Sex hormones have been hypothesized to explain the strong male predominance in esophageal adenocarcinoma, but evidence is needed. This study examined how circulating sex hormone levels influence future risk of ...
    • Prediagnostic circulating levels of sex hormones and survival in esophageal adenocarcinoma 

      Xie, Shao-hua; Ness-Jensen, Eivind; Langseth, Hilde; Gislefoss, Randi Elin; Mattsson, Fredrik; Lagergren, Jesper (Peer reviewed; Journal article, 2021)
      ex hormonal differences may contribute to the strong male predominance in esophageal adenocarcinoma (EAC), but whether sex hormone levels influence survival in EAC is unstudied. Our study aimed to assess associations between ...
    • Timing of HPV16-E6 antibody seroconversion before OPSCC: Findings from the HPVC3 consortium 

      Kreimer, Aimée R.; Ferreiro-Iglesias, Aida; Nygård, Mari; Bender, Noemi; Schroeder, Lea; Hildesheim, Alan; Robbins, Hilary A.; Pawlita, Michael; Langseth, Hilde; Schlecht, Nicolas F.; Tinker, Lesley Fels; Agalliu, Ilir; Smoller, Sylvia W.; Ness-Jensen, Eivind; Hveem, Kristian; D'Souza, Gypsyamber; Visvanathan, Kala; May, Betty; Ursin, Giske; Weiderpass, Elisabete; Giles, Graham G.; Milne, Roger L.; Cai, Qiuyin; Blot, William J.; Zheng, Wei; Weinstein, Stephanie J.; Albanes, Demetrius; Brenner, Nicole; Hoffman-Bolton, Judith; Kaaks, Rudolf; Barricarte, Aurelio; Tjønneland, Anne; Sacerdote, Carlotta; Trichopoulou, Antonia; Vermeulen, Roel C.H.; Huang, Wen-Yi; Freedman, Neal D.; Brennan, Paul J.; Waterboer, Tim; Johansson, Mattias (Journal article; Peer reviewed, 2019)
      Background Human papillomavirus type 16 (HPV16)-E6 antibodies are detectable in peripheral blood before diagnosis in the majority of HPV16-driven oropharyngeal squamous cell carcinoma (OPSCC), but the timing of seroconversion ...