Blar i NTNU Open på forfatter "Kvien, Tore Kristian"
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Adalimumab reduces hand bone loss in rheumatoid arthritis independent of clinical response: Subanalysis of the PREMIER study
Hoff, Mari; Kvien, Tore Kristian; Kälvesten, Johan; Elden, Aake; Kavanaugh, Arthur; Haugeberg, Glenn (Journal article; Peer reviewed, 2011)Background: Anti-TNF therapy has been shown to reduce radiographic joint damage in rheumatoid arthritis (RA) independent of clinical response. This has previously not been examined for periarticular bone loss, the ... -
Challenging issues in the follow-up and management of patients with psoriatic and rheumatoid arthritis
Michelsen, Brigitte (Doctoral theses at NTNU;2018:338, Doctoral thesis, 2018) -
Dickkopf-1 is associated with periarticular bone loss in patients with rheumatoid arthritis
Grandaunet, Berit Helen Jensen; Syversen, Silje Watterdal; Hoff, Mari; Van der Hejde, Désirée; Haugeberg, Glenn; Kvien, Tore Kristian; Standal, Therese (Journal article; Peer reviewed, 2013-11)Objective: To examine whether cytokines shown to suppress osteoblasts, Dickkopf-1 (DKK1) and hepatocyte growth factor (HGF), are associated with periarticular bone loss in rheumatoid arthritis (RA). Methods: RA patients ... -
The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial
Gjefsen, Elisabeth; Bråten, Lars Christian Haugli; Goll, Guro Løvik; Wigemyr, Monica; Bolstad, Nils; Valberg, Morten; Schistad, Ellina Iordanova; Marchand, Gunn Hege; Granviken, Fredrik; Selmer, Kaja Kristine; Johanessen, Anne Froholdt; Haugen, Anne Julsrud; Dagestad, Magnhild Hammersland; Vetti, Nils; Bakland, Gunnstein; Lie, Benedicte Alexandra; Haavardsholm, Espen A.; Nilsen, Aksel Thuv; Holmgard, Thor Einar; Kadar, Thomas; Kvien, Tore Kristian; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Espeland, Ansgar; Storheim, Kjersti; Zwart, John-Anker (Peer reviewed; Journal article, 2020)Low back pain is common and a significant number of patients experience chronic low back pain. Current treatment options offer small to moderate effects. Patients with vertebral bone marrow lesions visualized as Modic ... -
Effect of Therapeutic Drug Monitoring vs Standard Therapy During Infliximab Induction on Disease Remission in Patients With Chronic Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial
Syversen, Silje Watterdal; Goll, Guro Løvik; Jørgensen, Kristin Kaasen; Sandanger, Øystein; Sexton, Joseph; Olsen, Inge Christoffer; Gehin, Johanna Elin; Warren, David; Brun, Marthe Kirkesæther; Klaasen, Rolf; Karlsen, Lars Normann; Noraberg, Geir; Zettel, Camilla; Ljoså, Maud-Kristine Aga; Haugen, Anne Julsrud; Njålla, Rune Johan; Bruun, Trude J; Seeberg, Kathrine; Michelsen, Brigitte; Strand, Eldri Kveine; Skorpe, Svanaug; Blomgren, Ingrid; Bragnes, Yngvill; Dotterud, Christian; Thune, Turid Jorunn; Ystrøm, Carl Magnus; Torp, Roald; Pawel, Mielnik; Mørk, Cato; Kvien, Tore Kristian; Jahnsen, Jørgen; Bolstad, Nils; Haavardsholm, Espen A. (Peer reviewed; Journal article, 2021)Importance: Proactive therapeutic drug monitoring (TDM), defined as individualized drug dosing based on scheduled monitoring of serum drug levels, has been proposed as an alternative to standard therapy to maximize efficacy ... -
Efficacy and Safety of CT-P13 in Inflammatory Bowel Disease after Switching from Originator Infliximab: Exploratory Analyses from the NOR-SWITCH Main and Extension Trials
Jørgensen, Kristin Kaasen; Goll, Guro Løvik; Sexton, Joe; Bolstad, Nils; Olsen, Inge C.; Asak, Øivind Wessel; Berset, Ingrid Prytz; Blomgren, Ingrid; Dvergsnes, Katrine; Florholmen, Jon; Frigstad, Svein Oskar; Henriksen, Magne; Hagfors, Jon; Huppertz-Hauss, Gert; Haavardsholm, Espen Andre; Klaasen, Rolf Anton; Moum, Bjørn; Noraberg, Geir; Prestegård, Ulf; Rydning, Jan Henrik; Sagatun, Liv; Seeberg, Kathrine; Torp, Roald; Vold, Cecilia; Warren, David J.; Ystrøm, Carl Magnus; Lundin, Knut Erik Aslaksen; Kvien, Tore Kristian; Jahnsen, Jørgen (Peer reviewed; Journal article, 2020)Background - The NOR-SWITCH main and extension trials demonstrated that switching from originator to biosimilar infliximab (CT-P13) is efficacious and safe across six diseases. However, a subgroup analysis of Crohn’s disease ... -
Health-related quality of life in patients with psoriatic and rheumatoid arthritis: Data from the prospective multicentre NOR-DMARD study compared with Norwegian general population controls
Michelsen, Brigitte; Uhlig, Till; Sexton, Joseph; Heijde, Desirée van der; Hammer, Hilde Berner; Kristianslund, Eirik; Wierød, Ada; Bakland, Gunnstein; Rødevand, Erik; Krøll, Frode; Loge, Jon Håvard; Haugeberg, Glenn; Kvien, Tore Kristian (Journal article; Peer reviewed, 2018)Objectives To compare (1) Short Form-36 (SF-36) Physical Component Summary (PCS) and Mental Component Summary (MCS), scale scores and Short Form-6 dimensions (SF-6D) between patients with rheumatoid arthritis (RA) and ... -
Long‐term efficacy and safety of biosimilar infliximab (CT‐P13) after switching from originator infliximab: Open‐label extension of the NOR‐SWITCH trial
Goll, Guro Løvik; Jørgensen, Kristin Kaasen; Sexton, Joseph; Olsen, Inge Christoffer; Bolstad, Nils; Haavardsholm, Espen A.; Lundin, Knut Erik Aslaksen; Tveit, Kåre Steinar; Lorentzen, Merete; Berset, Ingrid Prytz; Fevang, Bjørg-Tilde Svanes; Kalstad, Synnøve; Ryggen, Kristin; Warren, David; Klaasen, Rolf; Asak, Øivind Wessel; Baigh, Somyeh; Blomgren, Ingrid; Brenna, Øystein; Bruun, Trude J; Dvergsnes, Katrine; Frigstad, Svein Oskar; Myrnes, Inger; Hatten, Ingvild Helgheim; Huppertz-Hauss, Gert; Henriksen, Magne; Hoie, Sunniva S.; Krogh, Jan Reidar; Midtgard, Irina P.; Mielnik, Pawel; Moum, Bjørn; Noraberg, Geir; Poyan, Armin; Prestegård, Ulf; Rashid, Haroon Ur; Strand, Eldri Kveine; Skjetne, Kristine; Seeberg, Kathrine; Torp, Roald; Ystrøm, Carl Magnus; Vold, Cecilia; Zettel, Camilla C.; Waksvik, Kenneth; Gulbrandsen, Bjørn; Hagfors, Jon; Mørk, Cato; Jahnsen, Jørgen; Kvien, Tore Kristian (Journal article; Peer reviewed, 2019)Background and objectives The 52‐week, randomized, double‐blind, noninferiority, government‐funded NOR‐SWITCH trial demonstrated that switching from infliximab originator to less expensive biosimilar CT‐P13 was not ... -
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Saevarsdottir, Saedis; Stefansdottir, Lilja; Sulem, Patrick; Thorleifsson, Gudmar; Ferkingstad, Egil; Rutsdottir, Gudrun; Glintborg, Bente; Westerlind, Helga; Grondal, Gerdur; Loft, Isabella C; Sorensen, Signe Bek; Lie, Benedicte Alexandra; Brink, Mikael; Arlestig, Lisbeth; Arnthorsson, Asgeir Orn; Baecklund, Eva; Banasik, Karina; Bank, Steffen; Bjorkman, Lena I; Ellingsen, Torkell; Erikstrup, Christian; Frei, Oleksandr; Gjertsson, Inger; Gudbjartsson, Daniel F; Gudjonsson, Sigurjon A; Halldorsson, Gisli H; Hendricks, Oliver; Hillert, Jan; Hogdall, Estrid; Jacobsen, Søren; Jensen, Dorte Vendelbo; Jonsson, Helgi Freyr; Kastbom, Alf; Kockum, Ingrid; Kristensen, Salome; Kristjansdottir, Helga; Larsen, Margit H; Linauskas, Asta; Hauge, Ellen-Margrethe; Loft, Anne G; Ludviksson, Bjorn R; Lund, Sigrun H; Markusson, Thorsteinn; Masson, Gisli; Melsted, Pall; Moore, Kristjan H S; Munk, Heidi; Nielsen, Kaspar R; Norddahl, Gudmundur L; Oddsson, Asmundur; Olafsdottir, Thorunn A; Olason, Pall I; Olsson, Tomas; Ostrowski, Sisse Rye; Hørslev-Petersen, Kim; Rognvaldsson, Solvi; Sanner, Helga; Silberberg, Gilad N; Stefansson, Hreinn; Sørensen, Erik; Sørensen, Inge J; Turesson, Carl; Bergman, Thomas; Alfredsson, Lars; Kvien, Tore Kristian; Brunak, Søren; Steinsson, Kristján; Andersen, Vibeke; Andreassen, Ole; Rantapää-Dahlqvist, Solbritt; Hetland, Merete Lund; Klareskog, Lars; Askling, Johan; Padyukov, Leonid; Pedersen, Ole Bv; Thorsteinsdottir, Unnur; Jonsdottir, Ingileif; Stefansson, Kari (Peer reviewed; Journal article, 2022)Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% ... -
Switching from originator infliximab to biosimilar CT-P13 compared with maintained treatment with originator infliximab (NOR-SWITCH): a 52-week, randomised, double-blind, non-inferiority trial
Jørgensen, Kristin Kaasen; Inge Christoffer, Olsen; Goll, Guro Løvik; Lorentzen, Merete; Bolstad, Nils; Haavardsholm, Espen A.; Lundin, Knut Erik Aslaksen; Mørk, Cato; Jahnsen, Jørgen; Kvien, Tore Kristian (Journal article; Peer reviewed, 2017)Background TNF inhibitors have improved treatment of Crohn's disease, ulcerative colitis, spondyloarthritis, rheumatoid arthritis, psoriatic arthritis, and chronic plaque psoriasis, but are expensive therapies. The aim ...