Browsing NTNU Open by Author "Kroustallaki, Pinelopi"

Now showing items 1-4 of 4

    • DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development 

      Quiles-Jiménez, Ana M T; Gregersen, Ida; Segers, Filip; Skarpengland, Tonje; Kroustallaki, Pinelopi; Yang, Kuan; Kong, Xiang Yi; Lauritzen, Knut Husø; Olsen, Maria Belland; Karlsen, Tom Rune; Nyman, Tuula Anneli; Sagen, Ellen Lund; Bjerkeli, Vigdis; Suganthan, Rajikala; Nygård, Ståle; Scheffler, Katja; Prins, Jurriën; Van der Veer, Eric; Øgaard, Jonas; Fløisand, Yngvar; Jørgensen, Helle F.; Holven, Kirsten Bjørklund; Biessen, Erik A.L.; Nilsen, Hilde; Dahl, Tuva Børresdatter; Holm, Sverre; Bennett, Martin R.; Aukrust, Pål; Bjørås, Magnar; Halvorsen, Bente (Peer reviewed; Journal article, 2021)
      Background and aims Atherogenesis involves a complex interaction between immune cells and lipids, processes greatly influenced by the vascular smooth muscle cell (VSMC) phenotype. The DNA glycosylase NEIL3 has previously ...

    • NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length 

      Karlsen, Tom Rune; Olsen, Maria Belland; Kong, Xiang Yi; Yang, Kuan; Quiles-Jiménez, Ana M T; Kroustallaki, Pinelopi; Holm, Sverre; Lines, Glenn Terje; Aukrust, Pål; Skarpengland, Tonje; Bjørås, Magnar; Dahl, Tuva Børresdatter; Nilsen, Hilde; Gregersen, Ida; Halvorsen, Bente (Peer reviewed; Journal article, 2022)
      Deficiency of NEIL3, a DNA repair enzyme, has significant impact on mouse physiology, including vascular biology and gut health, processes related to aging. Leukocyte telomere length (LTL) is suggested as a marker of ...

    • SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing 

      Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra; Jobert, Laure; Alsøe, Lene; Sætrom, Pål; Gagos, Sarantis; Nilsen, Hilde (Journal article; Peer reviewed, 2019)
      Telomerase biogenesis is a complex process where several steps remain poorly understood. Single-strand-selective uracil-DNA glycosylase (SMUG1) associates with the DKC1-containing H/ACA ribonucleoprotein complex, which is ...

    • SMUG1 regulates fat homeostasis leading to a fatty liver phenotype in mice 

      Carracedo Huroz, Sergio; Lirussi, Lisa; Alsøe, Lene; Segers, Filip; Wang, Changliang; Bartosova, Zdenka; Bohov, Pavol; Tekin, Nuriye Basdag; Kong, Xiang Yi; Esbensen, Qin Ying; Chen, Liang; Wennerström, Anna Berit; Kroustallaki, Pinelopi; Ceolotto, Deborah; Tönjes, Anke; Berge, Rolf Kristian; Bruheim, Per; Wong, Garry; Böttcher, Yvonne; Halvorsen, Bente; Nilsen, Hilde (Journal article; Peer reviewed, 2022)