• The Burden of Human Bocavirus 1 in Hospitalized Children with Respiratory Tract Infections 

      Jalving, Hedda Trømborg ; Heimdal, Inger; Valand, Jonas; Risnes, Kari; Krokstad, Sidsel; Nordbø, Svein Arne; Døllner, Henrik; Christensen, Andreas (Peer reviewed; Journal article, 2023)
      Background Human bocavirus 1 (HBoV1) is frequently codetected with other viruses, and detected in asymptomatic children. Thus, the burden of HBoV1 respiratory tract infections (RTI) has been unknown. Using HBoV1-mRNA ...
    • Comparing Human Metapneumovirus and Respiratory Syncytial Virus: Viral Co-Detections, Genotypes and Risk Factors for Severe Disease 

      Moe, Nina; Krokstad, Sidsel; Stenseng, Inger Heimdal; Christensen, Andreas; Skanke, Lars Høsøien; Risnes, Kari; Nordbø, Svein Arne; Døllner, Henrik (Journal article; Peer reviewed, 2017)
      Background It is unclarified as to whether viral co-detection and human metapneumovirus (HMPV) genotypes relate to clinical manifestations in children with HMPV and lower respiratory tract infection (LRTI), and if the ...
    • Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis 

      Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo; Espevik, Terje; Nordbø, Svein Arne; Døllner, Henrik; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2016)
      Human metapneumovirus (hMPV) causes severe airway infection in children that may be caused by an unfavorable immune response. The nature of the innate immune response to hMPV in naturally occurring infections in children ...
    • Detection of spliced mRNA from human bocavirus 1 in clinical samples from children with respiratory tract infections 

      Christensen, Andreas; Døllner, Henrik; Skanke, Lars Høsøien; Krokstad, Sidsel; Moe, Nina; Nordbø, Svein Arne (Journal article; Peer reviewed, 2013)
      Human bocavirus 1 (HBoV1) is a parvovirus associated with respiratory tract infections (RTIs) in children, but a causal relation has not yet been confirmed. To develop a qualitative reverse transcription PCR to detect ...
    • Detection of subgenomic mRNA from endemic human coronavirus OC43 and NL63 compared to viral genomic loads, single virus detection and clinical manifestations in children with respiratory tract infections 

      Heimdal, Inger; Lysvand, Hilde; Krokstad, Sidsel; Christensen, Andreas; Døllner, Henrik; Nordbø, Svein Arne (Peer reviewed; Journal article, 2022)
      Background The importance of endemic human coronavirus (HCoV) in children has been insufficiently elucidated upon. Our aims were to develop subgenomic (sg) mRNA tests for HCoV species OC43 and NL63, and to evaluate the ...
    • Etablering av Real-Time PCR for deteksjon av Cutibacterium acnes 

      Kupen, Marita; Fredheim, Katrine Weilin (Bachelor thesis, 2021)
      Cutibacterium acnes er en gram positiv, anaerob stavbakterie som inngår i hudens normalflora. Bakterien kan være årsak til postoperative infeksjoner, da bakterien fester seg til proteser og kirurgisk utstyr. Per i dag ...
    • Etablering av real-time PCR for påvisning av toksisk sjokk toksin hos Staphylococcus aureus 

      Hovdal, Kristin; Bruvoll, Lin Gunhild Rygg (Bachelor thesis, 2019)
      Bakgrunnen for dette prosjektet er at Avdeling for Medisinsk Mikrobiologi ved St. Olavs Hospital hadde behov for å etablere en real-time PCR metode for å påvise genet tst, hos Staphylococcus Aureus, som gir Toksisk ...
    • Genotyping of human adenovirus C by tiled amplicon sequencing 

      Toftemo, Anna Matilde (Master thesis, 2022)
      adenovirus (HAdV) er et vanlig humanpatogent virus som vanligvis forårsaker milde og selvbegrensende sykdommer i øvre luftveier eller i gastrointestinaltraktus. Alvorlige og livstruende infeksjoner kan imidlertid oppstå, ...
    • Hospitalized Children With Common Human Coronavirus Clinical Impact of Codetected Respiratory Syncytial Virus and Rhinovirus 

      Heimdal, Inger; Valand, Jonas; Krokstad, Sidsel; Moe, Nina; Christensen, Andreas; Risnes, Kari Ravndal; Nordbø, Svein Arne; Døllner, Henrik (Peer reviewed; Journal article, 2022)
      Background: The clinical impact of common human coronavirus (cHCoV) remains unclear. We studied the clinical manifestations of pediatric cHCoV infections and the possible modifying effects of codetected human rhinovirus ...
    • Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe. 

      Benschop, Kimberley; Broberg, Eeva; Hodcroft, E; Schmitz, D; Albert, Jan; Baicus, A; Bailly, Jean-Luc; Baldvinsdottir, Gudrun; Berginc, N; Blomqvist, S; Böttcher, S; Brytting, M; Bujaki, Erika; Cabrerizo, Maria; Celma, Cristina; Cinek, Ondrej; Claas, Eric CJ; Cremer, Jeroen; Dean, Jonathan; Dembinski, Jennifer Lynn; Demchyshyna, Iryna; Diedrich, Sabine; Dudman, Susanne Gjeruldsen; Dunning, Jake; Dyrdak, Robert; Emmanouil, Mary; Farkas, Agnes; De Gascun, Cillian; Fournier, Guillaume; Georgieva, Irina; Gonzalez-Sanz, Ruben; van Hooydonk-Elving, Jolanda; Jääskeläinen, A. J.; Jancauskaite, Ruta; Keeren, Kathrin; Fischer, Thea Kølsen; Krokstad, Sidsel; Nikolaeva–Glomb, Lubomira; Novakova, Ludmila; Midgley, SE; Mirand, Audrey; Molenkamp, Richard; Morley, Ursula; Mossong, Joël; Muralyte, Svajune; Murk, Jean-Luc; Nguyen, Trung; Nordbø, Svein Arne; Österback, Riikka; Pas, Suzan; Pellegrinelli, Laura; Pogka, Vassiliki; Prochazka, Birgit; Rainetova, Petra; Van Ranst, Marc; Roorda, Lieuwe; Schuffenecker, Isabelle; Schuurman, Rob; Stoyanova, Asya; Templeton, Kate E.; Verweij, Jaco J.; Voulgari-Kokota, Androniki; Vuorinen, Tytti; Wollants, Elke; Wolthers, Katja; Zakikhany, Katherina; Neher, Richard; Harvala, Heli; Simmonds, Peter (Journal article; Peer reviewed, 2021)
      In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016–2018. Most ...
    • Parechovirus A in Hospitalized Children With Respiratory Tract Infections: A 10-Year-Long Study From Norway 

      Skanke, Lars Høsøien; Lysvand, Hilde; Heimdal, Inger; Moe, Nina; Krokstad, Sidsel; Christensen, Andreas; Risnes, Kari; Nordbø, Svein Arne; Døllner, Henrik (Peer reviewed; Journal article, 2021)
      Background. The role of Parechovirus A (PeV-A) in hospitalized children with respiratory tract infections (RTIs) is unclear. We studied the occurrence and impact of PeV-A over 10 years. Methods. Children from Sør-Trøndelag ...
    • Respiratory Virus Detection and Clinical Diagnosis in Children Attending Day Care 

      Moe, Nina; Pedersen, Bård; Nordbø, Svein Arne; Skanke, Lars Høsøien; Krokstad, Sidsel; Smyrnaios, Anastasios; Døllner, Henrik (Journal article; Peer reviewed, 2016)
      Background: Respiratory viruses often have been studied in children with respiratory tract infection (RTI), but less knowledge exists about viruses in asymptomatic children. We have studied the occurrence of a broad ...
    • The Burden of Human Metapneumovirus and Respiratory Syncytial Virus Infections in Hospitalized Norwegian Children 

      Moe, Nina; Stenseng, Inger Heimdal; Krokstad, Sidsel; Christensen, Andreas; Skanke, Lars Høsøien; Risnes, Kari; Nordbø, Svein Arne; Døllner, Henrik (Journal article; Peer reviewed, 2017)
      Background. The burden of severe human metapneumovirus (HMPV) respiratory tract infections (RTIs) in European children has not been clarified. We assessed HMPV in Norwegian children and compared hospitalization rates for ...
    • Viral and atypical bacterial detection in young nepalese children hospitalized with severe pneumonia 

      Mathisen, Maria; Basnet, Sudha; Christensen, Andreas; Sharma, Arun; Tylden, Garth; Krokstad, Sidsel; Valentiner-Branth, Palle; Strand, Tor Arne (Peer reviewed; Journal article, 2021)
      Respiratory viruses cause a substantial proportion of respiratory tract infections in children but are underrecognized as a cause of severe pneumonia hospitalization in low-income settings. We employed 22 real-time PCR ...