• APOBEC3A/B deletion polymorphism and endometrial cancer risk 

      Sofiyeva, Nigar; Krakstad, Camilla; Halle, Mari Kyllesø; O'Mara, Tracy A.; Romundstad, Pål Richard; Hveem, Kristian; Vatten, Lars Johan; Lønning, Per Eystein; Gansmo, Liv Beathe; Knappskog, Stian (Journal article; Peer reviewed, 2022)
    • Automated segmentation of endometrial cancer on MR images using deep learning 

      Hodneland, Erlend; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Solteszova, Veronika; Zanna, Antonella; Fasmer, Kristine Eldevik; Krakstad, Camilla; Lundervold, Arvid; Lundervold, Alexander Selvikvåg; Salvesen, Øyvind; Erickson, Bradley J.; Haldorsen, Ingfrid S (Peer reviewed; Journal article, 2021)
      Preoperative MR imaging in endometrial cancer patients provides valuable information on local tumor extent, which routinely guides choice of surgical procedure and adjuvant therapy. Furthermore, whole-volume tumor analyses ...
    • Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients 

      Tangen, Ingvild Løberg; Kopperud, Reidun Kristin; Visser, Nicole C.M.; Staff, Anne Cathrine; Tingulstad, Solveig; Marcickiewicz, Janusz; Amant, Frédéric; Bjørge, Line; Pijnenborg, Johanna M.A.; Salvesen, Helga; Werner, Henrica Maria Johanna; Trovik, Jone; Krakstad, Camilla (Journal article; Peer reviewed, 2017)
      Background: Several studies have identified L1 cell adhesion molecule (L1CAM) as a strong prognostic marker in endometrial cancer. To further underline the clinical usefulness of this biomarker, we investigated L1CAM as ...
    • High visceral fat percentage is associated with poor outcome in endometrial cancer 

      Mauland, Karen Klepsland; Eng, Øyvin Andre Solberg; Ytre-Hauge, Sigmund; Tangen, Ingvild Løberg; Berg, Anna; Salvesen, Helga; Salvesen, Øyvind; Krakstad, Camilla; Trovik, Jone; Høivik, Erling Andre; Werner, Henrica Maria Johanna; Mellgren, Gunnar; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2017)
      Despite evidence of increased endometrial cancer (EC) risk in obese women, the impact of obesity on clinical and histological phenotype is poorly understood. This study explored abdominal fat volumes and fat distribution ...
    • Interobserver agreement and prognostic impact for MRI–based 2018 FIGO staging parameters in uterine cervical cancer 

      Wagner-Larsen, Kari Strøno; Lura, Njål Gjærde; Salvesen, Øyvind; Halle, Mari Kyllesø; Forsse, David Erik; Trovik, Jone; Smit, Noeska Natasja; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2022)
      Objectives To evaluate the interobserver agreement for MRI–based 2018 International Federation of Gynecology and Obstetrics (FIGO) staging parameters in patients with cervical cancer and assess the prognostic value of ...
    • Longitudinal effects of adjuvant chemotherapy and lymph node staging on patient-reported outcomes in endometrial cancer survivors: a prospective cohort study 

      Forsse, David Erik; Barbero, Mark L.; Werner, Henrica Maria Johanna; Woie, Kathrine; Nordskar, Nina Jebens; Berge Nilsen, Elisabeth; Ellstrøm Engh, Marie; Vistad, Ingvild; Rege, Astri; Sævik-Lode, Margaret; Andreasen, Stine; Haldorsen, Ingfrid S.; Trovik, Jone; Krakstad, Camilla (Peer reviewed; Journal article, 2021)
      Background - Most patients with endometrial cancer with localized disease are effectively treated and survive for a long time. The primary treatment is hysterectomy, to which surgical staging procedures may be added to ...
    • MRI-assessed tumor-free distance to serosa predicts deep myometrial invasion and poor outcome in endometrial cancer 

      Dybvik, Julie Andrea; Fasmer, Kristine Eldevik; Ytre-Hauge, Sigmund; Husby, Jenny Hild Aase; Salvesen, Øyvind; Stefansson, Ingunn Marie; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2022)
      Objectives To explore the diagnostic accuracy of preoperative magnetic resonance imaging (MRI)-derived tumor measurements for the prediction of histopathological deep (≥ 50%) myometrial invasion (pDMI) and prognostication ...
    • MRI-based radiomic signatures for pretreatment prognostication in cervical cancer 

      Wagner-Larsen, Kari Strøno; Hodneland, Erlend; Fasmer, Kristine Eldevik; Lura, Njål; Woie, Kathrine; Bertelsen, Bjørn; Salvesen, Øyvind Olav; Halle, Mari Kyllesø; Smit, Noeska Natasja; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2023)
      Background Accurate pretherapeutic prognostication is important for tailoring treatment in cervical cancer (CC). Purpose To investigate whether pretreatment MRI-based radiomic signatures predict disease-specific ...
    • Preoperative 18F-FDG PET/CT tumor markers outperform MRI-based markers for the prediction of lymph node metastases in primary endometrial cancer 

      Fasmer, Kristine Eldevik; Gulati, Ankush; Dybvik, Julie Andrea; Ytre-Hauge, Sigmund; Salvesen, Øyvind; Trovik, Jone; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2020)
      Objectives To compare the diagnostic accuracy of preoperative 18F-FDG PET/CT and MRI tumor markers for prediction of lymph node metastases (LNM) and aggressive disease in endometrial cancer (EC). Methods Preoperative ...
    • Preoperative pelvic MRI and 2-[18F]FDG PET/CT for lymph node staging and prognostication in endometrial cancer—time to revisit current imaging guidelines? 

      Fasmer, Kristine Eldevik; Gulati, Ankush; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Lura, Njål Gjærde; Salvesen, Øyvind; Forsse, David Erik; Trovik, Jone; Pijnenborg, Johanna M. A.; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2022)
      Objective This study presents the diagnostic performance of four different preoperative imaging workups (IWs) for prediction of lymph node metastases (LNMs) in endometrial cancer (EC): pelvic MRI alone (IW1), MRI and ...
    • Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer 

      Ytre-Hauge, Sigmund; Salvesen, Øyvind; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2020)
      BACKGROUND To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ...
    • Visceral fat percentage for prediction of outcome in uterine cervical cancer 

      Eide, Agnes J.; Halle, Mari Kyllesø; Lura, Njål; Fasmer, Kristine Eldevik; Wagner-Larsen, Kari Strøno; Forsse, David Erik; Bertelsen, Bjørn; Salvesen, Øyvind Olav; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2023)
      Objective The prognostic role of adiposity in uterine cervical cancer (CC) is largely unknown. Abdominal fat distribution may better reflect obesity than body mass index. This study aims to describe computed tomography ...
    • What MRI-based tumor size measurement is best for predicting long-term survival in uterine cervical cancer? 

      Lura, Njål Gjærde; Wagner-Larsen, Kari Strøno; Forsse, David Erik; Trovik, Jone; Halle, Mari Kyllesø; Bertelsen, Bjørn; Salvesen, Øyvind; Woie, Kathrine; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022)
    • Whole-volume tumor MRI radiomics for prognostic modeling in endometrial cancer 

      Fasmer, Kristine Eldevik; Hodneland, Erlend; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Trovik, Jone; Salvesen, Øyvind; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2020)
      Background In endometrial cancer (EC), preoperative pelvic MRI is recommended for local staging, while final tumor stage and grade are established by surgery and pathology. MRI‐based radiomic tumor profiling may aid in ...