• A Versatile and Robust Serine Protease Inhibitor Scaffold from Actinia tenebrosa 

      Chen, Xingchen; Leahy, Darren; Van Haeften, Jessica; Hartfield, Perry; Prentis, Peter J.; van der Burg, Chloé; Surm, Joachim M.; Pavasovic, Ana; Madio, Bruno; Hamilton, Brett R.; King, Glenn F.; Undheim, Eivind Andreas Baste; Brattsand, Maria; Harris, Jonathan M. (Journal article; Peer reviewed, 2019)
      Serine proteases play pivotal roles in normal physiology and a spectrum of patho-physiological processes. Accordingly, there is considerable interest in the discovery and design of potent serine protease inhibitors for ...
    • Missiles of mass disruption: Composition and glandular origin of venom used as a projectile defensive weapon by the assassin bug Platymeris rhadamanthus 

      Walker, Andrew A.; Robinson, Samuel D.; Undheim, Eivind Andreas Baste; Jin, Jiayi; Han, Xiao; Fry, Bryan G.; Vetter, Irina; King, Glenn F. (Journal article; Peer reviewed, 2019)
      Assassin bugs (Reduviidae) produce venoms that are insecticidal, and which induce pain in predators, but the composition and function of their individual venom components is poorly understood. We report findings on the ...
    • Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities 

      Nixon, Samantha A.; Robinson, Samuel D.; Agwa, Akello J.; Walker, Andrew A.; Choudhary, Shivani; Touchard, Axel; Undheim, Eivind Andreas Baste; Robertson, Alan; Vetter, Irina; Schroeder, Christina I.; Kotze, Andrew C.; Herzig, Volker; King, Glenn F. (Peer reviewed; Journal article, 2021)
      In the face of increasing drug resistance, the development of new anthelmintics is critical for controlling nematodes that parasitise livestock. Although hymenopteran venom toxins have attracted attention for applications ...
    • Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider 

      Finol-Urdaneta, Rocio K.; Ziegman, Rebekah; Dekan, Zoltan; McArthur, Jeffrey R.; Heitmann, Stewart; Luna-Ramirez, Karen; Tae, Han-Shen; Mueller, Alexander; Starobova, Hana; Chin, Yanni K.-Y.; Wingerd, Joshua S.; Undheim, Eivind Andreas Baste; Cristofori-Armstrong, Ben; Hill, Adam P.; Herzig, Volker; King, Glenn F.; Vetter, Irina; Rash, Lachlan D.; Adams, David J.; Alewood, Paul F. (Journal article; Peer reviewed, 2022)
    • A pain-causing and paralytic ant venom glycopeptide 

      Robinson, Samuel D.; Kambanis, Lucas; Clayton, Daniel; Hinneburg, Hannes; Corcilius, Leo; Mueller, Alexander; Walker, Andrew A.; Keramidas, Angelo; Kulkarni, Sameer S.; Jones, Alun; Vetter, Irina; Thaysen-Andersen, Morten; Payne, Richard J.; King, Glenn F.; Undheim, Eivind Andreas Baste (Journal article; Peer reviewed, 2021)
      Ants (Hymenoptera: Formicidae) are familiar inhabitants of most terrestrial environments. Although we are aware of the ability of many species to sting, knowledge of ant venom chemistry remains limited. Herein, we describe ...
    • A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals 

      Eagles, David A.; Saez, Natalie J.; Krishnarjuna, Bankala; Bradford, Julia J.; Chin, Yanni K.-Y.; Starobova, Hana; Mueller, Alexander; Reichelt, Melissa E.; Undheim, Eivind Andreas Baste; Norton, Raymond S.; Thomas, Walter G.; Vetter, Irina; King, Glenn F.; Robinson, Samuel D. (Peer reviewed; Journal article, 2022)
      Venoms are excellent model systems for studying evolutionary processes associated with predator–prey interactions. Here, we present the discovery of a peptide toxin, MIITX2-Mg1a, which is a major component of the venom of ...
    • Tentacle Morphological Variation Coincides with Differential Expression of Toxins in Sea Anemones 

      Ashwood, Lauren M.; Mitchell, Michaela; Madio, Bruno; Hurwood, David A.; King, Glenn F.; Undheim, Eivind Andreas Baste; Norton, Raymond S.; Prentis, Peter J. (Journal article; Peer reviewed, 2021)
      Phylum Cnidaria is an ancient venomous group defined by the presence of cnidae, specialised organelles that serve as venom delivery systems. The distribution of cnidae across the body plan is linked to regionalisation of ...