• Baseline and Exercise Predictors of VO2peak in Systolic Heart Failure Patients: Results from SMARTEX-HF 

      Karlsen, Trine; Videm, Vibeke; Halle, Martin; Ellingsen, Øyvind; Støylen, Asbjørn; Dalen, Håvard; Delagardelle, Charles; Larsen, Alf Inge; Hole, Torstein; Mezzani, Alessandro; Craenenbrock, EM; Beckers, Patrick; Pressler, Axel; Christle, JW; Winzer, Ephraim; Mangner, Norman; Woitek, Felix; Höllriegel, Robert; Snoer, Martin; Feiereisen, Patrick; Valborgland, Torstein; Linke, Axel; Prescott, Eva Irene Bossano (Journal article; Peer reviewed, 2019)
      Purpose To investigate baseline, exercise testing, and exercise training-mediated predictors of change in peak oxygen uptake (VO2peak) from baseline to 12-week follow-up (ΔVO2peak) in a post-hoc analysis from the SMARTEX ...
    • Blood Volume, Hemoglobin Mass, and Peak Oxygen Uptake in Older Adults: The Generation 100 Study 

      Lundgren, Kari Margrethe; Aspvik, Nils Petter; Langlo, Knut Asbjørn Rise; Braaten, Tonje Bjørndal; Wisløff, Ulrik; Stensvold, Dorthe; Karlsen, Trine (Peer reviewed; Journal article, 2021)
      Purpose: To investigate the association between blood volume, hemoglobin mass (Hbmass), and peak oxygen uptake (VO2peak) in healthy older adults. Methods: Fifty fit or unfit participants from the prospective randomized ...
    • Determinants and reference values for blood volume and total hemoglobin mass in women and men 

      Oberholzer, Laura; Montero, David; Robach, Paul; Siebenmann, Christoph; Ryrsøe, Camilla Koch; Bonne, Thomas C.; Breenfeldt Andersen, Andreas; Bejder, Jacob; Karlsen, Trine; Edvardsen, Elisabeth; Rønnestad, Bent; Hamarsland, Håvard; Cepeda-Lopez, Ana C.; Rittweger, Jörn; Treff, Gunnar; Ahlgrim, Christoph; Almquist, Nicki Winfield; Hallén, Jostein; Lundby, Carsten (Peer reviewed; Journal article, 2023)
      Blood volume (BV) is an important clinical parameter and is usually reported per kg of body mass (BM). When fat mass is elevated, this underestimates BV/BM. One aim was to study if differences in BV/BM related to sex, age, ...
    • Effect of lower extremity functional electrical stimulation pulsed isometric contractions on arm cycling peak oxygen uptake in spinal cord injured individuals 

      Brurok, Berit; Tørhaug, Tom; Karlsen, Trine; Leivseth, Gunnar; Helgerud, Jan; Hoff, Jan (Journal article; Peer reviewed, 2013)
      Objective: To compare peak oxygen uptake (VO2peak) between: (i) functional electrical stimulation lower extremity pulsed isometric muscle contractions combined with arm cycling (FES iso hybrid), (ii) functional electrical ...
    • Effects of upper-body sprint-interval training on strength and endurance capacities in female cross-country skiers 

      Vandbakk, Kristine; Welde, Boye; Hovstein, Andrea; Baumgart, Julia Kathrin; Ettema, Gertjan; Karlsen, Trine; Sandbakk, Øyvind (Journal article; Peer reviewed, 2017)
      This study compared the effects of adding upper-body sprint-intervals or continuous double poling endurance training to the normal training on maximal upper-body strength and endurance capacity in female cross-country ...
    • Exercise and obstructive sleep apnoea: a 24-week follow-up study 

      Karlsen, Trine; Engstrøm, Morten; Steinshamn, Sigurd Loe (Peer reviewed; Journal article, 2022)
      Objective Report on long-term follow-up results in the apnoea hypopnea index (AHI) and self-reported daytime sleepiness in participants with moderate to severe obstructive sleep apnoea at 12 weeks after completion of a ...
    • Exercise training and high-sensitivity cardiac troponin T in patients with heart failure with reduced ejection fraction 

      Koppen, Elias; Omland, Torbjørn; Larsen, Alf Inge; Karlsen, Trine; Linke, Axel; Prescott, Eva Irene Bossano; Halle, Martin; Dalen, Håvard; Delagardelle, Charles; Hole, Torstein; van Craenenbroeck, Emeline M.; Beckers, Paul; Ellingsen, Øyvind; Feiereisen, Patrick; Valborgland, Torstein; Videm, Vibeke (Journal article; Peer reviewed, 2021)
      Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ...
    • Exercise training and high-sensitivity cardiac troponin T in patients with heart failure with reduced ejection fraction 

      Koppen, Elias; Omland, Torbjørn; Larsen, Alf Inge; Karlsen, Trine; Linke, Axel; Prescott, Eva Irene Bossano; Halle, Martin; Dalen, Håvard; Delagardelle, Charles; Hole, Torstein; van Craenenbroeck, Emeline M.; Beckers, Paul; Ellingsen, Øyvind; Feiereisen, Patrick; Valborgland, Torstein; Videm, Vibeke (Peer reviewed; Journal article, 2021)
      Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ...
    • High Intensity Interval Training for Maximizing Health Outcomes 

      Karlsen, Trine; Aamot, Inger Lise; Haykowsky, Mark; Rognmo, Øivind (Journal article; Peer reviewed, 2017)
      Regular physical activity and exercise training are important actions to improve cardiorespiratory fitness and maintain health throughout life. There is solid evidence that exercise is an effective preventative strategy ...
    • High-intensity interval training improves obstructive sleep apnoea 

      Karlsen, Trine; Nes, Bjarne; Tjønna, Arnt Erik; Engstrøm, Morten; Støylen, Asbjørn; Steinshamn, Sigurd Loe (Journal article; Peer reviewed, 2017)
      Background Three hours per week of vigorous physical activity is found to be associated with reduced odds of sleep-disordered breathing. Aim To investigate whether 12 weeks of high-intensity interval training (HIIT) ...
    • High-Intensity Interval Training in Patients with Heart Failure with Reduced Ejection Fraction 

      Ellingsen, Øyvind; Halle, Martin; Conraads, Viviane; Støylen, Asbjørn; Dalen, Håvard; Delagardelle, Charles; Larsen, Alf Inge; Hole, Torstein; Mezzani, Alessandro; Van Craenenbroeck, Emeline M.; Videm, Vibeke; Beckers, Paul; Christle, Jeffrey W.; Winzer, Ephraim; Mangner, Norman; Woitek, Felix; Höllriegel, Robert; Pressler, Axel; Monk-Hansen, Tea; Snoer, Martin; Feiereisen, Patrick; Valborgland, Torstein; Kjekshus, John; Hambrecht, Rainer; Gielen, Stephan; Karlsen, Trine; Prescott, Eva; Linke, Axel (Journal article; Peer reviewed, 2017)
      Background: Small studies have suggested that high-intensity interval training (HIIT) is superior to moderate continuous training (MCT) in reversing cardiac remodeling and increasing aerobic capacity in patients with heart ...
    • How to Be 80 Year Old and Have a VO2max of a 35 Year Old 

      Karlsen, Trine; Leinan, Ingeborg Megård; Bækkerud, Fredrik Hjulstad; Lundgren, Kari Margrethe; Tari, Atefe R; Steinshamn, Sigurd Loe; Støylen, Asbjørn; Rognmo, Øivind (Peer reviewed; Journal article, 2015)
      Background. To discuss the cardiovascular and pulmonary physiology and common risk factors of an 80-year-old man with a world record maximal oxygen uptake of 50 mL·kg−1·min−1. Methods. Case report. Results. His maximal ...
    • Intensity Control During Block-Periodized High-Intensity Training: Heart Rate and Lactate Concentration During Three Annual Seasons in World-Class Cross-Country Skiers 

      Karlsen, Trine; Solli, Guro Strøm; Samdal, Svein Tore; Sandbakk, Øyvind (Peer reviewed; Journal article, 2020)
      Purpose: To describe heart rate (HR) and blood lactate (Bla−) responses during high-intensity interval training (HIT) in a long-term block-periodized HIT regimen in world-class cross-country (XC) skiers. Methods: Data ...
    • Moderate continuous or high intensity interval exercise in heart failure with reduced ejection fraction: Differences between ischemic and non-ischemic etiology 

      Halle, Martin; Prescott, Eva Bossano; Craenenbroeck, Emeline M Van; Beckers, Paul; Videm, Vibeke; Karlsen, Trine; Feiereisen, Patrick; Winzer, Ephraim B.; Mangner, Norman; Snoer, Martin; Christle, Jeffrey W.; Dalen, Håvard; Støylen, Asbjørn; Esefeld, Katrin; Heitkamp, Melanie; Spanier, Bianca; Axel, Linke; Ellingsen, Øyvind; Delagardelle, Charles (Peer reviewed; Journal article, 2022)
      Background Exercise for heart failure (HF) with reduced ejection fraction (HFrEF) is recommended by guidelines, but exercise mode and intensities are not differentiated between HF etiologies. We, therefore, investigated ...
    • No Effect of Calanus Oil on Maximal Oxygen Uptake in Healthy Participants: A Randomized Controlled Study. 

      Tauschek, Lucas Christian; Røsbjørgen, Ragnhild; Dalen, Håvard; Larsen, Terje; Karlsen, Trine (Peer reviewed; Journal article, 2022)
      We aimed to investigate the long-term effect of daily Calanus oil supplementation on maximal oxygen uptake (VO2max) in healthy 30- to 50-year-old participants. The study was motivated by preclinical studies reporting ...
    • The Combined Association of Skeletal Muscle Strength and Physical Activity on Mortality in Older Women: The HUNT2 Study 

      Karlsen, Trine; Nauman, Javaid; Dalen, Håvard; Langhammer, Arnulf; Wisløff, Ulrik (Journal article, 2017)
      Objective To assess the isolated and combined associations of leg and arm strength with adherence to current physical activity guidelines with all-cause and cause-specific mortality in healthy elderly women. Patients ...
    • Training is Medicine; Endurance and Strength Training in Coronary Artery Disease and Health 

      Karlsen, Trine (Doktoravhandlinger ved NTNU, 1503-8181; 2008:194, Doctoral thesis, 2008)
      High aerobic intensity interval training at 90-95% of maximal heart rate is more effective than continuous training with low to moderate intensity in improving maximal oxygen uptake in healthy young men. Maximal cardiac ...