Blar i NTNU Open på forfatter "Jonasson, Christian"
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Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits
Nayor, Matthew; Short, Meghan I.; Rasheed, Humaira; Lin, Honghuang; Jonasson, Christian; Yang, Qiong; Hveem, Kristian; Felix, Janine F.; Morrison, Alanna C.; Wild, Philipp S.; Morley, Michael P.; Cappola, Thomas P.; Benson, Mark D.; Ngo, Debby; Sinha, Sumita; Keyes, Michelle J.; Shen, Dongxiao; Wang, Thomas J.; Larson, Martin G.; Brumpton, Ben Michael; Gerszten, Robert E.; Omland, Torbjørn; Vasan, Ramachandran S. (Peer reviewed; Journal article, 2020)Abstract Background: We used a large-scale, high-throughput DNA aptamer-based discovery proteomic platform to identify circulating biomarkers of cardiac remodeling and incident heart failure (HF) in community-dwelling ... -
Changes in primary care management of atrial fibrillation patients following the shift from warfarin to non-vitamin K antagonist oral anticoagulants: a Norwegian population based study
Halvorsen, Sigrun; Smith, Jørgen Anton; Söderdahl, Fabian; Thuresson, Marcus; Solli, Oddvar; Ulvestad, Maria; Jonasson, Christian (Peer reviewed; Journal article, 2022)Background To assess baseline characteristics, drug utilisation and healthcare use for oral anticoagulants (OACs) following the introduction of non-vitamin K antagonist oral anticoagulants among patients with atrial ... -
Characteristics, treatment patterns, and residual cardiovascular risk of patients with a first acute myocardial infarction: A nationwide population-based cohort study in Norway
Oberprieler, Nikolaus G.; Farahmand, Bahman; Cameron, Jamie; Brobert, Gunnar; Jonasson, Christian; Atar, Dan (Peer reviewed; Journal article, 2021)There are few nationwide descriptive studies of longitudinal drug use and residual cardiovascular risk in patients with myocardial infarction (MI) in contemporary clinical practice. The objectives of this work were to ... -
The comparative cardiovascular and renal effectiveness of sodium-glucose co-transporter-2 inhibitors and glucagon-like peptide-1 receptor agonists: A Scandinavian cohort study
Ueda, Peter; Wintzell, Viktor; Dahlqwist, Elisabeth; Eliasson, Björn; Svensson, Ann-Marie; Franzén, Stefan; Gudbjörnsdottir, Soffia; Hveem, Kristian; Jonasson, Christian; Melbye, Mads; Hviid, Anders; Svanström, Henrik; Pasternak, Björn (Peer reviewed; Journal article, 2021)Aim To assess the comparative cardiovascular and renal effectiveness of sodium-glucose co-transporter-2 (SGLT2) inhibitors versus glucagon-like peptide-1 (GLP-1) receptor agonists in routine clinical practice. Materials ... -
Comparison of dabigatran, rivaroxaban and apixaban for effectiveness and safety in atrial fibrillation; a nationwide cohort study
Rutherford, Ole-Christian Walter; Jonasson, Christian; Ghanima, Waleed Khalid; Halvorsen, Sigrun (Peer reviewed; Journal article, 2020)The aim of this study was to compare the risk of stroke or systemic embolism (SE) and major bleeding in patients with atrial fibrillation (AF) using dabigatran, rivaroxaban, and apixaban in routine clinical practice. Methods ... -
Effectiveness and safety of oral anticoagulants in elderly patients with atrial fibrillation
Rutherford, Ole-Christian Walter; Jonasson, Christian; Ghanima, Waleed; Söderdahl, Fabian; Halvorsen, Sigrun (Peer reviewed; Journal article, 2021)Objectives To assess the risk of stroke/systemic embolism (SE) and major bleeding associated with the use of oral anticoagulants in elderly patients with atrial fibrillation (AF) in a real-world population. Methods We ... -
Glucagon-Like Peptide 1 Receptor Agonists and Risk of Diabetic Retinopathy Complications: Cohort Study in Nationwide Registers From Two Countries
Ueda, Peter; Pasternak, Björn; Eliasson, Björn; Svensson, Ann-Marie; Franzén, Stefan; Gudbjörnsdóttir, Soffia; Hveem, Kristian; Jonasson, Christian; Melbye, Mads; Svanström, Henrik (Journal article; Peer reviewed, 2019)Post hoc analyses of the Trial to Evaluate Cardiovascular and Other Long-term Outcomes With Semaglutide in Subjects With Type 2 Diabetes (SUSTAIN-6) showed an increased risk of diabetic retinopathy complications associated ... -
Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development
Shah, Amil M.; Myhre, Peder Langeland; Arthur, Victoria; Dorbala, Pranav; Rasheed, Humaira; Buckley, Leo F.; Claggett, Brian; Liu, Guning; Ma, Jianzhong; Nguyen, Ngoc Quynh; Matsushita, Kunihiro; Ndumele, Chiadi; Tin, Adrienne; Hveem, Kristian; Jonasson, Christian; Dalen, Håvard; Boerwinkle, Eric; Hoogeveen, Ron C.; Ballantyne, Christie; Coresh, Josef; Omland, Torbjørn; Yu, Bing (Peer reviewed; Journal article, 2024)Heart failure (HF) causes substantial morbidity and mortality but its pathobiology is incompletely understood. The proteome is a promising intermediate phenotype for discovery of novel mechanisms. We measured 4877 plasma ... -
Metabolic syndrome and the plasma proteome: from association to causation
Elhadad, Mohamed; Wilson, Rory; Zaghlool, Shaza B; Huth, Cornelia; Gieger, Christian; Grallert, Harald; Graumann, Johannes; Rathmann, Wolfgang; Koenig, Wolfgang; Sinner, Moritz F.; Hveem, Kristian; Suhre, Karsten; Thorand, Barbara; Jonasson, Christian; Waldenberger, Melanie; Peters, Annette (Peer reviewed; Journal article, 2021)Background The metabolic syndrome (MetS), defined by the simultaneous clustering of cardio-metabolic risk factors, is a significant worldwide public health burden with an estimated 25% prevalence worldwide. The pathogenesis ... -
New score for assessing bleeding risk in patients with atrial fibrillation treated with NOACs
Rutherford, Ole-Christian Walter; Jonasson, Christian; Ghanima, Waleed Khalid; Holst, René; Halvorsen, Sigrun (Journal article; Peer reviewed, 2018)Background Information is needed on bleeding risk factors specific for patients with atrial fibrillation (AF) treated with non-vitamin K oral anticoagulants (NOACs). We aimed to identify risk factors in a large real-world ... -
Plasma protein patterns as comprehensive indicators of health
Williams, Stephen; Kivimäki, Mika; Langenberg, Claudia; Hingorani, Aroon D.; Casas, Juan P.; Bouchard, Claude; Jonasson, Christian; Sarzynski, Mark A.; Shipley, Martin J.; Leigh, Alexander; Ash, Jessica; Bauer, Tim; Chadwick, Jessica; Kirk DeLisle, Robert; Datta, Gargi; Hagar, Yolanda; Hinterberg, Michael; Ostroff, Rachel; Weiss, Sophie; Ganz, Peter; Wareham, Nicholas J. (Journal article; Peer reviewed, 2019) -
Use of liraglutide and risk of major cardiovascular events: a register-based cohort study in Denmark and Sweden
Svanström, Henrik; Ueda, Peter; Melbye, Mads; Eliasson, Björn; Svensson, Ann Mari; Franzen, Stefan; Gudbjörnsdóttir, Soffia; Hveem, Kristian; Jonasson, Christian; Pasternak, Björn (Journal article; Peer reviewed, 2019) -
Use of sodium-glucose co-transporter 2 inhibitors and risk of serious renal events: Scandinavian cohort study
Pasternak, Björn; Wintzell, Viktor; Mellbye, Mads; Eliasson, Björn; Svensson, Ann-Marie; Franzén, Stefan; Gudbjörnsdóttir, Soffia; Hveem, Kristian; Jonasson, Christian; Svanström, Henrik; Ueda, Peter (Peer reviewed; Journal article, 2020)OBJECTIVE To assess the association between use of sodiumglucose co-transporter 2 (SGLT2) inhibitors and risk of serious renal events in data from routine clinical practice. DESIGN Cohort study using an active comparator, ...