Browsing NTNU Open by Author "Jolicoeur, Adrienne S"
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Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita; Sætrom, Pål; Habib, Nagy; Drake, Justin M; Schwertfeger, Kathryn L; Freedman, Tanya S. (Journal article; Peer reviewed, 2019)The activity of Src-family kinases (SFKs), which phosphorylate immunoreceptor tyrosine-based activation motifs (ITAMs), is a critical factor regulating myeloid-cell activation. We reported previously that the SFK LynA is ...