Blar i NTNU Open på forfatter "Johansson, Mikael"
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The blood proteome of imminent lung cancer diagnosis
Albanes, Demetrius; Alcala, Karine; Alcala, Nicolas; Amos, Christopher I.; Arslan, Alan A.; Bassett, Julie K.; Brennan, Paul; Cai, Qiuyin; Chen, Chu; Feng, Xiaoshuang; Freedman, Neal D.; Guida, Florence; Hung, Rayjean J.; Hveem, Kristian; Johansson, Mikael; Johansson, Mattias; Koh, Woon-Puay; Langhammer, Arnulf; Milne, Roger L.; Muller, David; Onwuka, Justina; Sørgjerd, Elin Pettersen; Robbins, Hilary A.; Sesso, Howard D.; Severi, Gianluca; Shu, Xiao-Ou; Sieri, Sabina; Smith-Byrne, Karl; Stevens, Victoria; Tinker, Lesley; Tjønneland, Anne; Visvanathan, Kala; Wang, Ying; Wang, Renwei; Weinstein, Stephanie; Yuan, Jian-Min; Zahed, Hana; Zhang, Xuehong; Zheng, Wei (Peer reviewed; Journal article, 2023)Identification of risk biomarkers may enhance early detection of smoking-related lung cancer. We measured between 392 and 1,162 proteins in blood samples drawn at most three years before diagnosis in 731 smoking-matched ... -
Circulating concentrations of biomarkers and metabolites related to Vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations
Midttun, Øivind; Theofylaktopoulou, Despoina; Mccann, Adrian; Fanidi, Anouar; Muller, David C.; Meyer, Klaus; Ulvik, Arve; Zheng, Wei; Shu, Xiao-Ou; Xiang, Yong-Bing; Prentice, Ross; Thomson, Cynthia A.; Pettinger, Mary; Giles, Graham G.; Hodge, Allison; Cai, Qiuyin; Blot, William J.; Wu, Jie; Johansson, Mikael; Hultdin, Johan; Grankvist, Kjell; Stevens, Victoria L.; McCullough, Marjorie L.; Weinstein, Stephanie J.; Albanes, Demetrius; Langhammer, Arnulf; Hveem, Kristian; Næss, Marit; Sesso, Howard D.; Gaziano, J. Michael; Buring, Julie E.; Lee, I-Min; Severi, Gianluca; Zhang, Xuehong; Han, Jiali; Stampfer, Meir J.; Smith-Warner, Stephanie A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Yuan, Jian-Min; Butler, Lesley M.; Koh, Woon-Puay; Wang, Renwei; Gao, Yu-Tang; Ericson, Ulrika; Sonestedt, Emily; Ziegler, Regina G.; Freedman, Neal D.; Visvanathan, Kala; Jones, Miranda R.; Relton, Caroline; Brennan, Paul; Johansson, Mattias; Ueland, Per Magne (Journal article; Peer reviewed, 2017)Background: Circulating concentrations of biomarkers that are related to vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also been influenced by the ... -
Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)
Larose, Tricia L; Guida, Florence; Anouar, Fanidi; Langhammer, Arnulf; Hveem, Kristian; Stevens, Victoria L.; Jacobs, Eric J.; Smith-Warner, Stephanie A.; Giovannucci, Edward; Albanes, Demetrius; Weinstein, Stephanie J.; Freedman, Neal D.; Prentice, Ross; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Wilkens, Lynne R.; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J; Hodge, Allison M.; Giles, Graham G.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Wang, Renwei; Yuan, Jian-Min; Gao, Yu-Tang; Koh, Woon-Puay; Shu, Xiao-Ou; Zheng, Wei; Xiang, Yong-Bing; Li, Honglan; Lan, Qing; Visvanathan, Kala; Hoffman Bolton, Judith; Ueland, Per Magne; Midttun, Øivind; Caporaso, Neil; Purdue, Mark; Sesso, Howard D.; Buring, Julie E.; Lee, I-Min; Gaziano, J. Michael; Manjer, Jonas; Brunnström, Hans; Brennan, Paul; Johansson, Mattias (Journal article; Peer reviewed, 2018)Background Self-reported smoking is the principal measure used to assess lung cancer risk in epidemiological studies. We evaluated if circulating cotinine—a nicotine metabolite and biomarker of recent tobacco exposure—provides ... -
Circulating high sensitivity C reactive protein concentrations and risk of lung cancer: Nested case-control study within Lung Cancer Cohort Consortium
Muller, David C.; Larose, Tricia L; Hodge, Allison; Guida, Florence; Langhammer, Arnulf; Grankvist, Kjell; Meyer, Klaus; Cai, Qiuyin; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Albanes, Demetrius; Giles, Graham G.; Sesso, Howard D.; Lee, I-Min; Gaziano, J. Michael; Yuan, Jian-Min; Hoffman Bolton, Judith; Buring, Julie E.; Visvanathan, Kala; Le Marchand, Loic; Purdue, Mark P.; Caporaso, Neil E.; Midttun, Øivind; Ueland, Per Magne; Prentice, Ross L.; Weinstein, Stephanie J.; Stevens, Victoria L.; Zheng, Wei; Blot, William J.; Shu, Xiao-Ou; Zhang, Xuehong; Xiang, Yong-Bing; Koh, Woon-Puay; Hveem, Kristian; Thomson, Cynthia A.; Pettinger, Mary; Engström, Gunnar; Brunnström, Hans; Milne, Roger L.; Stampfer, Meir J.; Han, Jiali; Johansson, Mikael; Brennan, Paul; Severi, Gianluca; Johansson, Mattias (Journal article; Peer reviewed, 2019)Objectives: Inflammation may play an important role in lung cancer pathogenesis. Previous studies have suggested an association between C-reactive protein (CRP) as a marker of inflammation, and risk of lung cancer, but ... -
Circulating markers of cellular immune activation in pre-diagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)
Huang, Joyce Yongxu; Larose, Tricia L; Luu, Hung N; Wang, Renwei; Fanidi, Anouar; Alcala, Karine; Stevens, Victoria L.; Weinstein, Stephanie J.; Albanes, Demetrius; Caporaso, Neil E.; Purdue, Mark P.; Ziegler, Regina G.; Freedman, Neal D.; Lan, Qing; Prentice, Ross L.; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J.; Shu, Xiao-Ou; Zheng, Wei; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loïc; Wilkens, Lynn R; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J.; Han, Jiali; Giles, Graham G.; Hodge, Allison M.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Langhammer, Arnulf; Hveem, Kristian; Xiang, Yong-Bing; Li, Hong-Lan; Gao, Yu-Tang; Visvanathan, Kala; Ueland, Per Magne; Midttun, Øivind; Ulvik, Arve; Buring, Julie E.; Lee, I-Min; Sesso, Howard D.; Gaziano, J. Michael; Manjer, Jonas; Relton, Caroline; Koh, Woon-Puay; Brennan, Paul; Johansson, Mattias; Yuan, Jian-Min (Journal article; Peer reviewed, 2019)Cell‐mediated immune suppression may play an important role in lung carcinogenesis. We investigated the associations for circulating levels of tryptophan, kynurenine, kynurenine:tryptophan ratio (KTR), quinolinic acid (QA) ... -
A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium
Midttun, Øivind; Ulvik, Arve; Meyer, Klaus; Zahed, Hana; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Behndig, Annelie F.; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loïc; Weinstein, Stephanie J.; Cai, Qiuyin; Arslan, Alan A.; Chen, Yu; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Robbins, Hilary A.; Brennan, Paul; Johansson, Mattias; Ueland, Per Magne (Peer reviewed; Journal article, 2023)Circulating concentrations of metabolites (collectively called kynurenines) in the kynurenine pathway of tryptophan metabolism increase during inflammation, particularly in response to interferon-gamma (IFN-γ). Neopterin ... -
Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults
Zahed, Hana; Johansson, Mattias; Ueland, Per Magne; Midttun, Øivind; Milne, Roger L.; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Grankvist, Kjell; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loic; Wilkens, Lynne R.; Weinstein, Stephanie J.; Albanes, Demetrius; Cai, Qiuyin; Blot, William J.; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Muller, David; Brennan, Paul; Guida, Florence; Robbins, Hilary A. (Peer reviewed; Journal article, 2021)Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary non-pathologically across population groups. We described variation in concentrations of biomarkers of one-carbon metabolism, vitamin ... -
Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis
Feng, Xiaoshuang; Muller, David C.; Zahed, Hana; Alcala, Karine; Guida, Florence; Smith-Byrne, Karl; Yuan, Jian-Min; Koh, Woon-Puay; Wang, Renwei; Milne, Roger L.; Bassett, Julie K.; Langhammer, Arnulf; Hveem, Kristian; Stevens, Victoria L.; Wang, Ying; Johansson, Mikael; Tjønneland, Anne; Tumino, Rosario; Sheikh, Mahdi; Johansson, Mattias; Robbins, Hilary A. (Peer reviewed; Journal article, 2023)Background To evaluate whether circulating proteins are associated with survival after lung cancer diagnosis, and whether they can improve prediction of prognosis. Methods We measured up to 1159 proteins in blood ... -
Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer
Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael; Johansson, Mattias; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål (Peer reviewed; Journal article, 2022)Lung cancer (LC) incidence is increasing globally and altered levels of microRNAs (miRNAs) in blood may contribute to identification of individuals with LC. We identified miRNAs differentially expressed in peripheral blood ... -
Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer
Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael; Johansson, Mattias; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål (Peer reviewed; Journal article, 2022)Lung cancer (LC) incidence is increasing globally and altered levels of microRNAs (miRNAs) in blood may contribute to identification of individuals with LC. We identified miRNAs differentially expressed in peripheral blood ... -
Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools
Feng, Xiaoshuang; Wu, Wendy Yi-Ying; Onwuka, Justina Ucheojor; Haider, Zahra; Alcala, Karine; Smith-Byrne, Karl; Zahed, Hana; Guida, Florence; Wang, Renwei; Bassett, Julie K.; Stevens, Victoria; Wang, Ying; Weinstein, Stephanie; Freedman, Neal D.; Chen, Chu; Tinker, Lesley; Nøst, Therese Haugdahl; Koh, Woon-Puay; Muller, David; Colorado-Yohar, Sandra M.; Tumino, Rosario; Hung, Rayjean J.; Amos, Christopher I.; Lin, Xihong; Zhang, Xuehong; Arslan, Alan A.; Sánchez, Maria-Jose; Sørgjerd, Elin Pettersen; Severi, Gianluca; Hveem, Kristian; Brennan, Paul; Langhammer, Arnulf; Milne, Roger L.; Yuan, Jian-Min; Melin, Beatrice; Johansson, Mikael; Robbins, Hilary A.; Johansson, Mattias (Peer reviewed; Journal article, 2023)Background We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available ...