Browsing NTNU Open by Author "Jayavelu, Naresh Doni"

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Integrative Systems Biology Approaches for Analyzing High-Throughput Data Applications to modeling of gene regulatory networks

Jayavelu, Naresh Doni (Doctoral thesis at NTNU;2015:68, Doctoral thesis, 2015)

Systems biology is relatively new and interdisciplinary field developed to study and understand the complex behavior of biological systems at systems level rather than at its individual elements. This is achieved by ...
Iterative sub-network component analysis enables reconstruction of large scale genetic networks

Jayavelu, Naresh Doni; Aasgaard, Lasse Svenkerud; Bar, Nadav (Journal article; Peer reviewed, 2015)

Background: Network component analysis (NCA) became a popular tool to understand complex regulatory networks. The method uses high-throughput gene expression data and a priori topology to reconstruct transcription factor ...