Browsing NTNU Open by Author "Janardhanan, Jeshina"

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    • Canonical notch activation in patients with scrub typhus: association with organ dysfunction and poor outcome 

      Damås, Jan Kristian; Otterdal, Kari; Astrup, Elisabeth; Lekva, Tove; Janardhanan, Jeshina; Michelsen, Annika Elisabet; Aukrust, Pål; Varghese, George M.; Ueland, Thor (Journal article; Peer reviewed, 2024)
      Purpose: The mechanisms that control inflammation in scrub typhus are not fully elucidated. The Notch pathways are important regulators of inflammation and infection, but have not been investigated in scrub typhus. Methods: ...

    • Secreted wnt antagonists in scrub typhus 

      Ueland, Thor; Astrup, Elisabeth; Otterdal, Kari; Lekva, Tove; Janardhanan, Jeshina; Prakash, John A.; Thomas, Kurien; Michelsen, Annika; Aukrust, Pål; Varghese, George M.; Damås, Jan Kristian (Peer reviewed; Journal article, 2021)
      Background The mechanisms that control local and systemic inflammation in scrub typhus have only been partially elucidated. The wingless (Wnt) signaling pathways are emerging as important regulators of inflammation and ...