Blar i NTNU Open på forfatter "Jalland, Clara Maria Osnes"
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DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease
Scheffler, Katja; Jalland, Clara Maria Osnes; Benestad, Sylvie L.; Moldal, Torfinn; Ersdal, Cecilie; Gunnes, Gjermund; Suganthan, Rajikala; Bjørås, Magnar; Tranulis, Michael A. (Peer reviewed; Journal article, 2020)The DNA glycosylase Neil2 is a member of the base excision repair (BER) family of enzymes, which are important for repair of oxidative DNA damage. Specifically, Neil2 participates in repair of oxidized bases in single-stranded ... -
Neil3 induced neurogenesis protects against prion disease during the clinical phase
Jalland, Clara Maria Osnes; Scheffler, Katja; Benestad, Sylvie Lafond; Moldal, Torfinn; Ersdal, Cecilie; Gunnes, Gjermund; Suganthan, Rajikala; Bjørås, Magnar; Tranulis, Michael A. (Journal article; Peer reviewed, 2016)Base excision repair (BER) is the major pathway for repair of oxidative DNA damage. Mice with genetic knockout of the BER enzyme Neil3 display compromised neurogenesis in the sub-ventricular zone of the lateral ventricle ... -
Stress resilience of spermatozoa and blood mononuclear cells without prion protein
Reiten, Malin Rokseth; Malachin, Giulia; Kommisrud, Elisabeth; Østby, Gunn Charlotte; Waterhouse, Karin Elisabeth; Krogenæs, Anette Kristine; Kusnierczyk, Anna; Bjørås, Magnar; Jalland, Clara Maria Osnes; Nekså, Liv Heidi; Røed, Susan Skogtvedt; Stenseth, Else-Berit; Myromslien, Frøydis Deinboll; Zeremichael, Teklu Tewoldebrhan; Bakkebø, Maren Kolltveit; Espenes, Arild; Tranulis, Michael A. (Journal article; Peer reviewed, 2018)The cellular prion protein PrPC is highly expressed in neurons, but also present in non-neuronal tissues, including the testicles and spermatozoa. Most immune cells and their bone marrow precursors also express PrPC. ...