• Cardiovascular models for personalised medicine: Where now and where next? 

      Hose, David Rodney; Lawford, Patricia V.; Huberts, Wouter; Hellevik, Leif Rune; Omholt, Stig William; van de Vosse, Frans (Journal article, 2019)
      The aim of this position paper is to provide a brief overview of the current status of cardiovascular modelling and of the processes required and some of the challenges to be addressed to see wider exploitation in both ...
    • Effect of side branch flow upon physiological indices in coronary artery disease 

      Gosling, Rebecca C.; Sturdy, Jacob; Morris, Paul D.; Fossan, Fredrik Eikeland; Hellevik, Leif Rune; Lawford, Patricia V.; Hose, David Rodney; Gunn, Julian P. (Peer reviewed; Journal article, 2020)
      Recent efforts have demonstrated the ability of computational models to predict fractional flow reserve from coronary artery imaging without the need for invasive instrumentation. However, these models include only larger ...
    • Parameter estimation for closed-loop lumped parameter models of the systemic circulation using synthetic data 

      Bjørdalsbakke, Nikolai Lid; Sturdy, Jacob; Hose, David Rodney; Hellevik, Leif Rune (Peer reviewed; Journal article, 2022)
      Physics-based models can be applied to describe mechanisms in both health and disease, which has the potential to accelerate the development of personalized medicine. The aim of this study was to investigate the feasibility ...
    • Predictive Physiological Modeling of Percutaneous Coronary Intervention - Is Virtual Treatment Planning the Future? 

      Gosling, Rebecca; Morris, Paul D.; Lawford, Patricia V.; Hose, David Rodney; Gunn, Julian P. (Journal article; Peer reviewed, 2018)
      Computational modeling has been used routinely in the pre-clinical development of medical devices such as coronary artery stents. The ability to simulate and predict physiological and structural parameters such as flow ...
    • Wearable technology and the cardiovascular system: the future of patient assessment 

      Williams, Gareth J; Al-Baraikan, Abdulaziz; Rademakers, Frank E; Ciravegna, Fabio; van de Vosse, Frans N; Lawrie, Allan; Rothman, Alexander; Ashley, Euan A; Wilkins, Martin R; Lawford, Patricia V; Omholt, Stig William; Wisløff, Ulrik; Hose, David Rodney; Chico, Timothy J A; Gunn, Julian P; Morris, Paul D (Peer reviewed; Journal article, 2023)
      The past decade has seen a dramatic rise in consumer technologies able to monitor a variety of cardiovascular parameters. Such devices initially recorded markers of exercise, but now include physiological and health-care ...