Blar i NTNU Open på forfatter "Hope, Sigrun"

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    • Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders 

      Reponen, Elina Johanna; Dieset, Ingrid; Tesli, Martin Steen; Mørch, Ragni Helene; Aas, Monica; Vedal, Trude Seselie Jahr; Haug, Elisabeth; Drange, Ole Kristian; Steen, Nils Eiel; Hope, Sigrun; Szabo, Attila; Gohar, Sherif Mostafa Mohamed Ahmed; Wedervang-Resell, Kirsten; Djurovic, Srdjan; Melle, Ingrid; Aukrust, Pål; Andreassen, Ole Andreas; Ueland, Thor (Peer reviewed; Journal article, 2020)
      Background: Cardiovascular disease (CVD) is a major cause of premature death in patients with psychotic disorders, where dyslipidemia occurs frequently. In the pathogenesis of these serious mental disorders, a low-grade ...

    • Event-Related Potentials in a Cued Go-NoGo Task Associated with Executive Functions in Adolescents with Autism Spectrum Disorder; A Case-Control Study 

      Høyland, Anne Lise; Øgrim, Geir; Lydersen, Stian; Hope, Sigrun; Engstrøm, Morten; Torske, Tonje; Nærland, Terje; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2017)
      Executive functions are often affected in autism spectrum disorders (ASD). The underlying biology is however not well known. In the DSM-5, ASD is characterized by difficulties in two domains: Social Interaction and Repetitive ...

    • Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia A comparison among participants between 2 and 53 years 

      Hope, Sigrun; Nærland, Terje; Høyland, Anne Lise; Torske, Tonje; Malt, Eva; Abrahamsen, Tore G; Nerhus, Mari; Wedervang-Resell, Kirsten; Lonning, Vera Louise Hiorth; Johannessen, Jarle; Steen, Nils Eiel; Agartz, Ingrid; Stenberg, Nina; Hundhausen, Thomas Eckhard; Mørkrid, Lars; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2020)
      Recent studies suggest that both high and low levels of vitamin B12 (vitB12) may have negative health impacts. We measured VitB12 in patients with the Neurodevelopmental disorders (ND) (n = 222), comprised of Autism Spectrum ...

    • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

      Szabo, Attila; O’Connell, Kevin; Ueland, Thor; Ahmed, Mashhood Sheikh; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John Abel; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Auten Weibell, Melissa; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2022)
      Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...

    • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

      Szabo, Attila; O'Connell, Kevin Sean; Ueland, Thor; Sheikh, Mashhood Ahmed; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2021)
      Background -Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...

    • Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors 

      Mørch, Ragni Helene; Dieset, Ingrid; Færden, Ann; Reponen, Elina Johanna; Hope, Sigrun; Hoseth, Eva Zsuzsanna; Gardsjord, Erlend Strand; Aas, Monica; Iversen, Trude; Joa, Inge; Morken, Gunnar; Agartz, Ingrid; Melle, Ingrid; Aukrust, Pål; Djurovic, Srdjan; Ueland, Thor; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2019)
      Background. Inflammation and immune activation have been implicated in the pathogenesis of severe mental disorders and cardiovascular disease (CVD). Despite high level of comorbidity, many studies of the immune system in ...

    • Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample 

      Johannessen, Tor Jarle; Nærland, Terje; Hope, Sigrun; Torske, Tonje; Høyland, Anne Lise; Strohmaier, Jana; Heiberg, Arvid; Rietschel, Marcella; Djurovic, Srdjan; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2017)
      Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial ...

    • Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study 

      Engh, John; Ueland, Thor; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Wedervang-Resell, Kirsten; Weibell, Melissa; Westlye, Lars Tjelta; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole (Peer reviewed; Journal article, 2021)
      Background Immune dysfunction has been implicated in the pathogenesis of schizophrenia and other nonaffective psychosis (SCZ), bipolar spectrum disorder (BIP) and major depressive disorder (MDD). The cytokines B cell-activating ...

    • Sex as a Moderator Between Parent Ratings of Executive Dysfunction and Social Difficulties in Children and Adolescents with Autism Spectrum Disorder 

      Torske, Tonje; Nærland, Terje; Quintana, Daniel; Hypher, Ruth Elizabeth; Kaale, Anett; Høyland, Anne Lise; Hope, Sigrun; Johannessen, Tor Jarle; Øie, Merete Glenne; Andreassen, Ole (Peer reviewed; Journal article, 2022)
      Girls and boys might differ in autistic symptoms and associated cognitive difficulties such as executive function (EF). We investigated sex differences in the relationship between parent rated EF and autistic symptoms in ...

    • Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation 

      Sheikh, Mashhood Ahmed; O'Connell, Kevin Sean; Lekva, Tove; Szabo, Attila; Akkouh, Ibrahim Ahmed; Osete, Jordi Requena; Agartz, Ingrid; Engh, John; Andreou, Dimitrios; Boye, Birgitte; Bøen, Erlend; Elvsåshagen, Torbjørn; Hope, Sigrun; Werner, Maren Caroline Frogner; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Melle, Ingrid; Drange, Ole Kristian; Morken, Gunnar; Nærland, Terje; Sørensen, Kjetil; Vaaler, Arne; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Peer reviewed; Journal article, 2022)
      Background Cell adhesion molecules (CAMs) orchestrate leukocyte trafficking and could link peripheral and neuroinflammation in patients with severe mental illness (SMI), by promoting inflammatory and immune-mediated ...