Browsing NTNU Open by Author "Hofsli, Eva"
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Agreement between Physicians' and Patients' Ratings of Performance Status in Metastatic Colorectal Cancer
Aamodt, Julie; Gravdal Rummø, Andrea (Master thesis, 2021)ABSTRACT Background Patient-reported outcome measures (PROMs) are increasingly used to evaluate and engage in patient's disease management, whilst the use of physician-assessed performance status (PS) is a well-estab ... -
Agreement between Physicians’ and Patients’ Ratings of Performance Status in Metastatic Colorectal Cancer
Aamodt, Julie; Gravdal Rummø, Andrea (Master thesis, 2021)ABSTRACT Background Patient-reported outcome measures (PROMs) are increasingly used to evaluate and engage in patient's disease management, whilst the use of physician-assessed performance status (PS) is a well-establi ... -
Aterosklerotisk kardiovaskulær sykdom og venøse tromboser hos pasienter med pankreaskreft
Sagredo - Thackwell, Sabina (Master thesis, 2023)Introduksjon Pankreaskreft er en sjelden og alvorlig kreftsykdom med økende insidens globalt. Prognosen er dårlig med lav overlevelse og kort gjennomsnittlig levetid. Pasienter med pankreaskreft har også økt risiko for ... -
Cancer Patients’ Perceived Value of a Smartphone App to Enhance the Safety of Home-Based Chemotherapy: Feasibility Study
Kongshaug, Nina; Skolbekken, John-Arne; Faxvaag, Arild; Hofsli, Eva (Journal article; Peer reviewed, 2020)Background: Oral anticancer therapies can be self-administered by patients outside the hospital setting, which poses challenges of adherence to a drug plan and monitoring of side effects. Modern information technology ... -
Chemotherapy for colorectal cancer - Physical exercise and quality of life
Hatlevoll, Ingunn (Doctoral theses at NTNU;2024:34, Doctoral thesis, 2024)Colorectal cancer (CRC) is the third most common cancer worldwide, the second most common cancer in Norway, and the second leading cause of cancer deaths both globally and nationally. In Norway, 4745 new cases were diagnosed ... -
Colorectal cancer patients’ experiences with supervised exercise during adjuvant chemotherapy—A qualitative study
Hatlevoll, Ingunn; Skolbekken, John-Arne; Oldervoll, Line Merethe; Wibe, Arne; Hofsli, Eva (Peer reviewed; Journal article, 2021)Background Colorectal cancer (CRC) is a common cancer worldwide, with increasing numbers surviving and living with long-term side effects from treatment. Physical exercise during or after treatment may have several beneficial ... -
Design, Development, and Evaluation of an mHealth App for Reporting of Side Effects During Cytostatic Treatment: Usability Test and Interview Study
Hægermark , Emil Carl Richard Aale ; Kongshaug, Nina Anita; Raj, Sunil Xavier; Hofsli, Eva; Faxvaag, Arild (Peer reviewed; Journal article, 2023)Background: Using mobile health (mHealth) interventions such as smartphone apps to deliver health services is an opportunity to engage patients more actively in their own treatment. Usability tests allow for the evaluation ... -
Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
Meltzer, Sebastian; Negård, Anne; Bakke, Kine Mari; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Flatmark, Kjersti; Ree, Anne Hansen (Journal article; Peer reviewed, 2022) -
The effect of BRAFV600E mutation on survival and treatment efficacy in vulnerable older patients with metastatic colorectal cancer – A post-hoc exploratory analysis of the randomized NORDIC9-study
Liposits, Gabor; Winther, Stine B.; Ryg, Jesper; Skuladottir, Halla; Möller, Sören; Hofsli, Eva; Shah, Carl-Henrik; Poulsen, Laurids Østergaard; Berglund, Åke; Qvortrup, Camilla; Osterlund, Pia; Glimelius, Bengt; Sorbye, Halfdan; Pfeiffer, Per (Peer reviewed; Journal article, 2023) -
First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial
Ree, Anne Hansen; Saltyte Benth, Jurate; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Johansen, Christin; Negård, Anne; Bjørnetrø, Tonje; Nilsen, Hilde; Berg, Jens Petter; Flatmark, Kjersti; Meltzer, Sebastian (Journal article; Peer reviewed, 2024)Background We evaluated first-line treatment of metastatic microsatellite-stable colorectal cancer with short-course oxaliplatin-based chemotherapy alternating with immune checkpoint blockade. Methods Patients were ... -
Germline pathogenic variants in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms
Venizelos, Andreas; Sorbye, Halfdan; Elvebakken, Hege; Perren, Aurel; Lothe, Inger Marie Bowitz; Couvelard, Anne; Hjortland, Geir Olav; Sundlöv, Anna; Svensson, Johanna; Garresori, Herish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Vestermark, Lene W.; Ladekarl, Morten; Tabaksblat, Elizaveta Mitkina; Knappskog, Stian (Peer reviewed; Journal article, 2023)High-grade gastroenteropancreatic (HG-GEP) neuroendocrine neoplasms (NENs) are highly aggressive cancers. The molecular etiology of these tumors remains unclear, and the prevalence of pathogenic germline variants in patients ... -
High-grade digestive neuroendocrine neoplasms. Impact of genetic alterations and morphologicalcharacteristics on outcome of first-line palliative chemotherapy
Elvebakken, Hege (Doctoral theses at NTNU;2023:353, Doctoral thesis, 2023)Høygradige nevroendokrine neoplasmer i fordøyelsessystemet. Innvirkninger av genforandringer på behandlingseffekt og overlevelse. Høygradige nevroendokrine neoplasmer (HG-NEN) utgående fra fordøyelsessystemet er en kreft ... -
Identification of metastasis-associated microRNAs in serum from rectal cancer patients
Mjelle, Robin; Sellæg, Kjersti; Sætrom, Pål; Thommesen, Liv; Sjursen, Wenche; Hofsli, Eva (Peer reviewed; Journal article, 2017)MicroRNAs (miRNAs) are promising prognostic and diagnostic biomarkers due to their high stability in blood. Here we investigate the expression of miRNAs and other noncoding (nc) RNAs in serum of rectal cancer patients. ... -
Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
Larsen, Stein Gunnar; Goscinski, Mariusz Adam; Dueland, Svein; Steigen, Sonja Eriksson; Hofsli, Eva; Torgunrud, A.; Lund-Iversen, Marius; Dagenborg, Vegar Johansen; Flatmark, Kjersti; Sorbye, Halfdan (Peer reviewed; Journal article, 2021)Patients with metastatic colorectal cancer (mCRC) carrying BRAF (mutBRAF) or KRAS mutation (mutKRAS) have an inferior prognosis after liver or lung surgery, whereas the prognostic role in the context of peritoneal metastasis ... -
MicroRNA as biomarkers in colorectal cancer
Sellæg, Kjersti (Master thesis, 2016)Colorectal cancer (CRC) is one of the worlds leading causes of cancer-related deaths in both men and women. Nearly 1.4 million new cases were reported in 2012 and over half of the cases ended in death. High mortality rates ... -
The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms
Venizelos, Andreas; Elvebakken, Hege; Perren, Aurel; Nikolaienko, Oleksii; Deng, Wei; Lothe, Inger Marie Bowitz; Couvelard, Anne; Hjortland, Geir Olav; Sundlöv, Anna; Svensson, Johanna; Garresori, Herish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Krogh, Merete; Sørbye, Halfdan; Knappskog, Stian (Peer reviewed; Journal article, 2021)High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are rare but have a very poor prognosis and represent a severely understudied class of tumours. Molecular data for HG GEP-NEN are limited, and ... -
Mutation Spectrum in Liquid Versus Solid Biopsies From Patients With Advanced astroenteropancreatic Neuroendocrine Carcinoma
Knappskog, Stian; Grob, Tobias; Venizelos, Andreas; Amstutz, Ursula; Hjortland, Geir Olav; Lothe, Inger Marie Bowitz; Kersten, Christian; Hofsli, Eva; Sundlöv, Anna; Elvebakken, Hege; Garresori, Herish; Couvelard, Anne; Svensson, Johanna; Sorbye, Halfdan; Perren, Aurel (Peer reviewed; Journal article, 2023)Purpose Gastroenteropancreatic neuroendocrine carcinomas (GEP-NEC) are rare and have a poor prognosis. Most GEP-NEC are diagnosed with metastatic disease, with only minor biopsies available for molecular diagnostics. We ... -
Nanoparticles, ultrasound and microbubble mediated drug delivery in cancer models
Fagerland, Stein-Martin Tilrum (Doctoral theses at NTNU;2020:97, Doctoral thesis, 2020)Denne avhandlingen omhandler forbedring av kreftbehandling gjennom økt levering av cellegift til kreftvev ved bruk av nanopartikler eller ultralyd kombinert med mikrobobler. Ved å kapsle cellegift inn i nanopartikler kan ... -
Physical exercise during adjuvant chemotherapy for colorectal cancer - a non-randomized feasibility study
Hatlevoll, Ingunn; Oldervoll, Line Merethe; Wibe, Arne; Stene, GB; Stafne, Signe Nilssen; Hofsli, Eva (Peer reviewed; Journal article, 2020)Background Colorectal cancer (CRC) is the third most common cancer worldwide, and a large proportion of the patients receive adjuvant oxaliplatin-based chemotherapy. Most of these experience chemotherapy-induced peripheral ... -
Prognostic value of baseline functional status measures and geriatric screening in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy – The randomized NORDIC9-study
Liposits, Gabor Isivan; Ryg, Jesper; Skuladottir, Halla; Winther, Stine B.; Möller, Sören; Hofsli, Eva; Shah, Carl-Henrik; Poulsen, Laurids Østergaard; Berglund, Åke; Qvortrup, Camilla; Osterlund, Pia; Glimelius, Bengt; Sorbye, Halfdan; Pfeiffer, Per (Peer reviewed; Journal article, 2022)Introduction Appropriate patient selection based on functional status is crucial when considering older adults for palliative chemotherapy. This pre-planned analysis of the randomized NORDIC9-study explored the prognostic ...