Browsing NTNU Open by Author "Healey, Andrew"
Now showing items 1-3 of 3
-
Acoustic Cluster Therapy (ACT) - pre-clinical proof of principle for local drug delivery and enhanced uptake.
van Wamel, Annemieke; Healey, Andrew; Sontum, Per C.; Kvåle, Svein; Bush, Nigel; Bamber, Jeffrey; Davies, Ruth Catharina de Lange (Journal article; Peer reviewed, 2016)Proof of principle for local drug delivery with Acoustic Cluster Therapy (ACT) was demonstrated in a human prostate adenocarcinoma growing in athymic mice, using near infrared (NIR) dyes as model molecules. A dispersion ... -
Acoustic Cluster Therapy (ACT) enhances the therapeutic efficacy of paclitaxel and Abraxane® for treatment of human prostate adenocarcinoma in mice
van Wamel, Annemieke; Sontum, Per C.; Healey, Andrew; Kvåle, Svein; Bush, Nigel; Bamber, Jeffrey; Davies, Ruth Catharina de Lange (Journal article; Peer reviewed, 2016)Acoustic cluster therapy (ACT) is a novel approach for ultrasound mediated, targeted drug delivery. In the current study, we have investigated ACT in combination with paclitaxel and Abraxane® for treatment of a subcutaneous ... -
Ultrafast Microscopy Imaging of Acoustic Cluster Therapy Bubbles: Activation and Oscillation
van Wamel, Annemieke; Mühlenpfordt, Melina; Hansen, Rune; Healey, Andrew; Villanueva, Flordeliza S.; Kotopoulis, Spiros; Davies, Catharina de Lange; Chen, Xucai (Peer reviewed; Journal article, 2022)Acoustic Cluster Therapy (ACT®) is a platform for improving drug delivery and has had promising pre-clinical results. A clinical trial is ongoing. ACT® is based on microclusters of microbubbles–microdroplets that, when ...