Blar i NTNU Open på forfatter "Haugen, Håvard Jostein"
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Biomimetic Highly Porous Nanocellulose-Nanohydroxyapatite Scaffolds for Bone Tissue Engineering
Korkeamäki, Jannika Timontytär; Rashad, Ahmad; Berstad, Kaia; Weber, Florian; Syverud, Kristin; Haugen, Håvard Jostein; Mustafa, Kamal Babikeir Elnour (Peer reviewed; Journal article, 2024)Wood-derived TEMPO-oxidized cellulose nanofibrils (CNFs) have potential as scaffolding for bone tissue engineering. Although biocompatible, the material lacks osteoconductive and appropriate mechanical properties. Incorporation ... -
Eggshell-derived amorphous calcium phosphate: Synthesis, characterization and bio-functions as bone graft materials in novel 3D osteoblastic spheroids model
Ma, Qianli; Rubenis, Kristaps; Sigurjonsson, Olafur E.; Hildebrand, Torben; Standal, Therese; Zemjane, Signe; Locs, Janis; Loca, Dagnija; Haugen, Håvard Jostein (Journal article, 2023)A multitude of autogenous/allogeneic and semi-synthetic bone graft materials have been developed to reconstruct the defective bone tissue but with high bio-cost and potential environmental pollution. With high calcium ... -
Osteocyte-Like Cells Differentiated From Primary Osteoblasts in an Artificial Human Bone Tissue Model
Munir, Arooj; Reseland, Janne Elin; Tiainen, Hanna; Haugen, Håvard Jostein; Sikorski, Pawel; Christiansen, Emil; Reinholt, Finn P.; Syversen, Unni; Solberg, Lene Bergendal (Peer reviewed; Journal article, 2023)In vitro models of primary human osteocytes embedded in natural mineralized matrix without artificial scaffolds are lacking. We have established cell culture conditions that favored the natural 3D orientation of the bone ... -
Significance of mechanical loading in bone fracture healing, bone regeneration, and vascularization
Ma, Qianli; Miri, Zahra; Haugen, Håvard Jostein; Moghanian, Amirhossein; Loca, Dagnija (Peer reviewed; Journal article, 2023)In 1892, J.L. Wolff proposed that bone could respond to mechanical and biophysical stimuli as a dynamic organ. This theory presents a unique opportunity for investigations on bone and its potential to aid in tissue repair. ... -
Stabilisation of amorphous calcium phosphate in polyethylene glycol hydrogels
Schweikle, Manuel; Bjørnøy, Sindre Hove; Van Helvoort, Antonius; Haugen, Håvard Jostein; Sikorski, Pawel; Tiainen, Hanna (Journal article; Peer reviewed, 2019)Acellular polymer-calcium phosphate composites are promising bone graft materials. Hydrogels are suitable for providing a temporary matrix, while calcium phosphate minerals serve as ion depots for calcium and phosphate ...