• Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial 

      Smenes, Benedikte; Bækkerud, Fredrik Hjulstad; Slagsvold, Katrine Hordnes; Hassel, Erlend; Wohlwend, Martin; Pinho, Maria; Høydal, Morten; Wisløff, Ulrik; Rognmo, Øivind; Wahba, Alexander (Journal article; Peer reviewed, 2018)
      OBJECTIVES During open-heart surgery, the myocardium experiences ischaemia–reperfusion injury. A single bout of moderate, 30-min exercise induces preconditioning and protects the heart from ischaemia–reperfusion injury ...
    • The association between normal lung function and peak oxygen uptake in patients with exercise intolerance and coronary artery disease 

      Rasch-Halvorsen, Øystein; Hassel, Erlend; Brumpton, Ben Michael; Jenssen, Haldor; Spruit, Martijn A.; Langhammer, Arnulf; Steinshamn, Sigurd Loe (Peer reviewed; Journal article, 2020)
      In coronary artery disease (CAD), exercise intolerance with reduced oxygen uptake at peak exercise (VO2peak) is assumed to primarily reflect cardiovascular limitation. However, oxygen transport and utilization depends on ...
    • Association between pulmonary function and peak oxygen uptake in elderly: the Generation 100 study 

      Hassel, Erlend; Stensvold, Dorthe; Halvorsen, Thomas; Wisløff, Ulrik; Langhammer, Arnulf; Steinshamn, Sigurd Loe (Peer reviewed; Journal article, 2015)
      Background Although reduced function of the respiratory system limits peak oxygen uptake in diseases affecting the lungs or airways, the healthy respiratory system is thought to have a spare capacity for oxygen transport ...
    • Cardiorespiratory Reference Data in Older Adults: The Generation 100 Study. 

      Stensvold, Dorthe; Bucher Sandbakk, Silvana; Viken, Hallgeir; Zisko, Nina; Reitlo, Line Skarsem; Nauman, Javaid; Gaustad, Svein Erik; Hassel, Erlend; Moufack, Marcel; Brønstad, Eivind; Aspvik, Nils Petter; Malmo, Vegard; Steinshamn, Sigurd Loe; Støylen, Asbjørn; Anderssen, Sigmund Alfred; Helbostad, Jorunn L.; Rognmo, Øivind; Wisløff, Ulrik (Journal article; Peer reviewed, 2017)
      Purpose: Cardiorespiratory fitness (CRF) is regarded a clinical vital sign, and accurate reference values for all age groups are essential. Little data exist on CRF and cardiorespiratory function in older adults. The aim ...
    • Effect of 5 years of exercise training on the cardiovascular risk profile of older adults: the Generation 100 randomized trial 

      Letnes, Jon Magne; Berglund, Ida Johnsen; Johnson, Kristin Espolin; Dalen, Håvard; Nes, Bjarne; Lydersen, Stian; Viken, Hallgeir; Hassel, Erlend; Steinshamn, Sigurd Loe; Vesterbekkmo, Elisabeth Kleivhaug; Støylen, Asbjørn; Reitlo, Line Skarsem; Zisko, Nina; Bækkerud, Fredrik Hjulstad; Tari, Atefe R; Ingebrigtsen, Jan Erik; Bucher Sandbakk, Silvana; Carlsen, Trude; Anderssen, Sigmund Alfred; Singh, Maria A. Fiatarone; Coombes, Jeff S.; Helbostad, Jorunn L.; Rognmo, Øivind; Wisløff, Ulrik; Stensvold, Dorthe (Peer reviewed; Journal article, 2021)
      Aims The aim of this study was to compare the effects of 5 years of supervised exercise training (ExComb), and the differential effects of subgroups of high-intensity interval training (HIIT) and moderate-intensity continuous ...
    • Effects of exercise training on pulmonary vessel muscularization and right ventricular function in an animal model of COPD 

      Hassel, Erlend; Berre, Anne Marie Ormbostad; Skjulsvik, Anne Jarstein; Steinshamn, Sigurd Loe (Journal article; Peer reviewed, 2014)
      Background Right ventricular dysfunction in COPD is common, even in the absence of pulmonary hypertension. The aim of the present study was to examine the effects of high intensity interval training (HIIT) on right ...
    • Lung function and aerobic capacity: The association between lung function parameters and peak oxygen uptake 

      Hassel, Erlend (Doctoral theses at NTNU;2018:103, Doctoral thesis, 2018)
      Lungefunksjon og aerob kapasitet - sammenhengen mellom lungefunksjon og maksimalt oksygenopptak Tilførsel av oksygen er en nøkkelfaktor for alle cellulære prosesser i mennesket. Ved fysiske anstrengelser går behovet for ...
    • Lung function and peak oxygen uptake in chronic obstructive pulmonary disease phenotypes with and without emphysema 

      Rasch-Halvorsen, Øystein; Steinshamn, Sigurd Loe; Langhammer, Arnulf; Hassel, Erlend; Brumpton, Ben Michael; Jenssen, Haldor; Spruit, Martijn A. (Journal article; Peer reviewed, 2021)
      Previous studies of associations of forced expiratory lung volume in one second (FEV1) with peak oxygen uptake (VO2peak) in chronic obstructive pulmonary disease (COPD) have not taken sex, age and height related variance ...
    • Lung function parameters improve prediction of VO2peak in an elderly population: The Generation 100 study. 

      Hassel, Erlend; Stensvold, Dorthe; Halvorsen, Thomas; Wisløff, Ulrik; Langhammer, Arnulf; Steinshamn, Sigurd Loe (Journal article; Peer reviewed, 2017)
      Peak oxygen uptake (VO2peak) is an indicator of cardiovascular health and a useful tool for risk stratification. Direct measurement of VO2peak is resource-demanding and may be contraindicated. There exist several non-exercise ...
    • The association between dynamic lung volume and peak oxygen uptake in a healthy general population: the HUNT study 

      Rasch-Halvorsen, Øystein; Steinshamn, Sigurd Loe; Hassel, Erlend; Brumpton, Ben Michael; Langhammer, Arnulf (Journal article; Peer reviewed, 2019)
      Background Although dynamic lung volume is not considered a limiting factor of peak oxygen uptake (VO2peak) in healthy subjects, an association between forced expiratory lung volume in one second (FEV1) and VO2peak has ...