Browsing NTNU Open by Author "Hanssen, Katrine Sjaastad"
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Dissecting the complexities of Alzheimer's disease: Engineering selectively vulnerable neural networks in vitro
Hanssen, Katrine Sjaastad (Doctoral theses at NTNU;2023:365, Doctoral thesis, 2023)Alzheimer’s disease (AD) is a progressive, neurodegenerative disease where accumulation of neuropathology can start up to two decades before symptom onset. With no cure for the disease, relevant models of AD are needed to ... -
Dissection and culturing of adult lateral entorhinal cortex layer II neurons from APP/PS1 Alzheimer model mice
Hanssen, Katrine Sjaastad; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna; Kobro-Flatmoen, Asgeir (Peer reviewed; Journal article, 2023)Background Primary neuronal cultures enable cell-biological studies of Alzheimer’s disease (AD), albeit typically non-neuron-specific. The first cortical neurons affected in AD reside in layer II of the lateralmost part ... -
Establishing lateral entorhinal cortex layer II-neuron cultures as a tool for the investigation of early Alzheimer's disease related changes
Hanssen, Katrine Sjaastad (Master thesis, 2019)Alzheimer’s disease is a slowly progressing and ultimately fatal neurodegenerative disease affecting more than 46 million people worldwide in 2018. The entorhinal cortex (EC), in particular the layer II of the domains ... -
Extraction and culturing of adult hippocampal and entorhinal neurons from Alzheimer model-animals
Niethammer, Salome Nora (Master thesis, 2022)Abstract will be available on 2027-12-31